Functional Mixed-Effects Modeling of Longitudinal Duchenne Muscular Dystrophy Electrical Impedance Myography Data Using State-Space Approach

Objective: Electrical impedance myography (EIM) is a quantitative and objective tool to evaluate muscle status. EIM offers the possibility to replace conventional physical functioning scores or quality of life measures, which depend on patient cooperation and mood. Methods: Here, we propose a functi...

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Bibliographic Details
Published in:	IEEE transactions on biomedical engineering Vol. 66; no. 6; pp. 1761 - 1768
Main Authors:	Kapur, Kush, Sanchez, Benjamin, Pacheck, Adam, Darras, Basil, Rutkove, Seward B., Selukar, Rajesh
Format:	Journal Article
Language:	English
Published:	United States IEEE 01.06.2019 The Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subjects:	Algorithms Bayesian analysis Biomarkers Biomedical measurement Child Clinical trials Confidence Covariance matrix Data models Deltoid Muscle - physiology Deltoid Muscle - physiopathology Diseases Duchenne's muscular dystrophy Dystrophy Electric Impedance Electrical impedance electrical impedance myography Electromyography - methods Functional data Humans Image Processing, Computer-Assisted - methods Impedance Kalman filtering Kalman filters Male Medical research mixed-effects models Modelling Mood Muscles Muscular dystrophy Muscular Dystrophy, Duchenne - diagnosis Muscular Dystrophy, Duchenne - physiopathology Quality of life Smoothing Smoothing methods smoothing splines Splines (mathematics) Trajectory measurement
ISSN:	0018-9294, 1558-2531, 1558-2531
Online Access:	Get full text
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