Hematological parameters in patients with acnes

Objective To compare complete blood count (CBC) parameters and inflammatory factors in the patients with different grade of acne vulgaris and healthy controls. Methods A total of 20 patients were enrolled in this study. Patients were divided into mild group and moderate‐to‐severe group based on the...

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Veröffentlicht in:Journal of cosmetic dermatology Jg. 22; H. 7; S. 2099 - 2104
Hauptverfasser: Chen, Tingqiao, Chen, Yangmei, Shao, Xinyi, Chen, Jiayi, Liu, Lin, Li, Yuxin, Pu, Yihuan, Chen, Jin
Format: Journal Article
Sprache:Englisch
Veröffentlicht: England John Wiley & Sons, Inc 01.07.2023
Schlagworte:
Acne
acne vulgaris
Antibiotics
Biomarkers
Blood platelets
Blood tests
Constipation
derived neutrophil‐to‐lymphocyte ratio
Dermatitis
Enzymes
Family medical history
Hematology
Inflammatory diseases
inflammatory factors
Leukocytes
lymphocyte to monocyte ratio
Lymphocytes
Neutrophils
Patients
systemic immune‐inflammation index
China
systemic immune-inflammation index
acne vulgaris
lymphocyte to monocyte ratio
derived neutrophil-to-lymphocyte ratio
inflammatory factors
ISSN:1473-2130, 1473-2165, 1473-2165
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Zusammenfassung:Objective To compare complete blood count (CBC) parameters and inflammatory factors in the patients with different grade of acne vulgaris and healthy controls. Methods A total of 20 patients were enrolled in this study. Patients were divided into mild group and moderate‐to‐severe group based on the acne severity, and compared to controls. Inflammatory factors (TNF‐α, IL‐6, IL‐8, and IL1‐α) detected by ELISA and complete blood count parameters (MPV, NLR, dNLR, PLR, LMR, and SII) obtained by routine blood tests were compared among the three group. Results All CBC parameters were not significantly elevated in patients with acne compared to healthy controls. However, the present studies have found that the inflammatory factors in acne patients were significantly elevated relative to healthy controls, and increase with the acne grade. Conclusions Inflammatory factors are convenient parameters to show inflammatory response to acne vulgaris, and may be a new clinical method for judging the acne grades of objectively. Considering the use of antibiotic, we believe that this metric worth further study.
Bibliographie:Tingqiao Chen and Yangmei Chen contributed equally to this work.
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ISSN:1473-2130
1473-2165
1473-2165
DOI:10.1111/jocd.15676