High‐Mannose Oligosaccharide Hemimimetics that Recapitulate the Conformation and Binding Mode to Concanavalin A, DC‐SIGN and Langerin

The “carbohydrate chemical mimicry” exhibited by sp2‐iminosugars has been utilized to develop practical syntheses for analogs of the branched high‐mannose‐type oligosaccharides (HMOs) Man3 and Man5. In these compounds, the terminal nonreducing Man residues have been substituted with 5,6‐oxomethylide...

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Vydané v:	Chemistry : a European journal Ročník 30; číslo 2; s. e202303041 - n/a
Hlavní autori:	Herrera‐González, Irene, González‐Cuesta, Manuel, Thépaut, Michel, Laigre, Eugénie, Goyard, David, Rojo, Javier, García Fernández, José M., Fieschi, Franck, Renaudet, Olivier, Nieto, Pedro M., Ortiz Mellet, Carmen
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Germany Wiley Subscription Services, Inc 08.01.2024 Wiley-VCH Verlag
Predmet:	Binding Sites Carbohydrates Chemical Sciences Chemistry Concanavalin A Concanavalin A - metabolism Conformation Epitopes glycomimetics high-mannose oligosaccharides Humans Lectins Lectins, C-Type - metabolism Mannose Mannose - chemistry Mannose-Binding Lectins - chemistry Mimicry Monosaccharides multivalency NMR Nuclear magnetic resonance Oligosaccharides Oligosaccharides - chemistry Phytochemicals Surface plasmon resonance carbohydrates glycomimetics multivalency lectins high-mannose oligosaccharides
ISSN:	0947-6539, 1521-3765, 1521-3765
On-line prístup:	Získať plný text
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