Assessment of Paravalvular Leak Severity and Thrombogenic Potential in Transcatheter Bicuspid Aortic Valve Replacements Using Patient-Specific Computational Modeling

Bicuspid aortic valve (BAV), the most common congenital valvular abnormality, generates asymmetric flow patterns and increased stresses on the leaflets that expedite valvular calcification and structural degeneration. Recently adapted for use in BAV patients, TAVR demonstrates promising performance,...

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Bibliographic Details
Published in:	Journal of cardiovascular translational research Vol. 15; no. 4; pp. 834 - 844
Main Authors:	Anam, Salwa B., Kovarovic, Brandon J., Ghosh, Ram P., Bianchi, Matteo, Hamdan, Ashraf, Haj-Ali, Rami, Bluestein, Danny
Format:	Journal Article
Language:	English
Published:	New York Springer US 01.08.2022
Subjects:	Aortic Valve - diagnostic imaging Aortic Valve - surgery Aortic Valve Stenosis - surgery Bicuspid Aortic Valve Disease Biomedical Engineering and Bioengineering Biomedicine Cardiology Computer Simulation Human Genetics Humans Medicine Medicine & Public Health Original Article Patient-Specific Modeling Transcatheter Aortic Valve Replacement - adverse effects Treatment Outcome Thrombogenicity Computational fluid dynamics (CFD) Paravalvular leakage (PVL) Transcatheter aortic valve replacement (TAVR) Bicuspid aortic valve (BAV) Transcatheter aortic valve implantation (TAVI) Patient-specific computational modeling
ISSN:	1937-5387, 1937-5395, 1937-5395
Online Access:	Get full text
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