Plasma lipidomics analysis finds long chain cholesteryl esters to be associated with Alzheimer’s disease

There is an urgent need for the identification of Alzheimer’s disease (AD) biomarkers. Studies have now suggested the promising use of associations with blood metabolites as functional intermediate phenotypes in biomedical and pharmaceutical research. The aim of this study was to use lipidomics to i...

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Veröffentlicht in:	Translational psychiatry Jg. 5; H. 1; S. e494
Hauptverfasser:	Proitsi, P, Kim, M, Whiley, L, Pritchard, M, Leung, R, Soininen, H, Kloszewska, I, Mecocci, P, Tsolaki, M, Vellas, B, Sham, P, Lovestone, S, Powell, J F, Dobson, R J B, Legido-Quigley, C
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London Nature Publishing Group UK 13.01.2015 Nature Publishing Group
Schlagworte:	631/378/340 692/53/2421 82/58 Aged Aged, 80 and over Alzheimer Disease - blood Alzheimer Disease - diagnosis Behavioral Sciences Biological Psychology Biomarkers - blood Case-Control Studies Cholesterol Esters - blood Chromatography, Liquid Cognitive Dysfunction - blood Cognitive Dysfunction - diagnosis Female Humans Male Mass Spectrometry Medicine & Public Health Multivariate Analysis Neurosciences Original original-article Pharmacotherapy Psychiatry Sensitivity and Specificity
ISSN:	2158-3188, 2158-3188
Online-Zugang:	Volltext
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