Development of diagnostic microsphere-based immunoassays for Heartland virus

•IgM and IgG microsphere immunoassays for Heartland virus were developed.•Both assays demonstrated >95 % sensitivity, specificity and accuracy.•Anti-HRTV IgM and anti-HRTV IgG was detected in human serum.•The HRTV microsphere immunoassays are intended as first-line diagnostic tools. Background. H...

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Bibliographic Details

Published in:	Journal of clinical virology Vol. 134; p. 104693
Main Authors:	Basile, Alison Jane, Horiuchi, Kalanthe, Goodman, Christin H., Kosoy, Olga, Panella, Amanda J., Velez, Jason O., Pastula, Daniel M., Brault, Aaron C., Staples, J. Erin, Calvert, Amanda E.
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 01.01.2021
Subjects:	Diagnosis Heartland virus Immunoglobulin G Immunoglobulin M MIA Microsphere immunoassay Heartland virus Immunoglobulin M Microsphere immunoassay Diagnosis MIA Immunoglobulin G
ISSN:	1386-6532, 1873-5967, 1873-5967
Online Access:	Get full text
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