Klebsiella pneumoniae producing bacterial toxin colibactin as a risk of colorectal cancer development - A systematic review

Microbiota can significantly contribute to colorectal cancer initiation and development. It was described that E. coli harbouring polyketide synthase (pks) genes can synthetize bacterial toxin colibactin, which was first described by Nougayrede's group in 2006. E. coli positive for pks genes we...

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Vydané v:	Toxicon (Oxford) Ročník 197; s. 126 - 135
Hlavní autori:	Strakova, Nicol, Korena, Kristyna, Karpiskova, Renata
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	England Elsevier Ltd 15.07.2021
Predmet:	adhesins Bacterial Toxins biomarkers cancer therapy Cancer-distinctive microbiota carcinogenesis Colibactin Colon colorectal neoplasms Colorectal Neoplasms - chemically induced digestive system DNA damage endotoxins Escherichia coli Humans Klebsiella pneumoniae loci meningitis microbiome multigene family Peptides polyketide synthases Polyketides - toxicity risk factors sequence analysis siderophores systematic review virulence ks Colon Cancer-distinctive microbiota Colibactin DNA damage Klebsiella pneumoniae
ISSN:	0041-0101, 1879-3150, 1879-3150
On-line prístup:	Získať plný text
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