Empagliflozin in Patients with Chronic Kidney Disease

The effects of empagliflozin in patients with chronic kidney disease who are at risk for disease progression are not well understood. The EMPA-KIDNEY trial was designed to assess the effects of treatment with empagliflozin in a broad range of such patients. We enrolled patients with chronic kidney d...

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Bibliographic Details
Published in:	The New England journal of medicine Vol. 388; no. 2; pp. 117 - 127
Main Authors:	Herrington, William G, Staplin, Natalie, Wanner, Christoph, Green, Jennifer B, Hauske, Sibylle J, Emberson, Jonathan R, Preiss, David, Judge, Parminder, Mayne, Kaitlin J, Ng, Sarah Y A, Sammons, Emily, Zhu, Doreen, Hill, Michael, Stevens, Will, Wallendszus, Karl, Brenner, Susanne, Cheung, Alfred K, Liu, Zhi-Hong, Li, Jing, Hooi, Lai Seong, Liu, Wen, Kadowaki, Takashi, Nangaku, Masaomi, Levin, Adeera, Cherney, David, Maggioni, Aldo P, Pontremoli, Roberto, Deo, Rajat, Goto, Shinya, Rossello, Xavier, Tuttle, Katherine R, Steubl, Dominik, Petrini, Michaela, Massey, Dan, Eilbracht, Jens, Brueckmann, Martina, Landray, Martin J, Baigent, Colin, Haynes, Richard
Format:	Journal Article
Language:	English
Published:	United States Massachusetts Medical Society 12.01.2023
Subjects:	Albumin Antidiabetics Benzhydryl Compounds - adverse effects Benzhydryl Compounds - therapeutic use Cardiology Cardiovascular Diseases - chemically induced Chronic Kidney Disease Clinical Medicine Clinical Medicine General Congestive heart failure Creatinine Creatinine - urine Death Design Diabetes Diabetes mellitus Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - drug therapy Disease Progression End-stage renal disease Endocrinology Epidermal growth factor receptors Glomerular Filtration Rate Heart failure Hemodialysis Hospitalization Humans Kidney - physiopathology Kidney diseases Kidney transplants Nephrology Patient safety Placebos Prevention Renal Insufficiency, Chronic - complications Renal Insufficiency, Chronic - drug therapy Sodium-Glucose Transporter 2 Inhibitors - adverse effects Sodium-Glucose Transporter 2 Inhibitors - therapeutic use Statistical analysis Values
ISSN:	0028-4793, 1533-4406, 1533-4406
Online Access:	Get full text
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