Supramolecular hydrogels based on cellulose for sustained release of therapeutic substances with antimicrobial and wound healing properties

•A cellulose-chalcone hydrogel containing carbon nanotubes was successfully developed.•The hydrogel was characterized by swelling tests, FT-IR spectroscopy, thermogravimetric analysis and SEM.•The hydrogel allows the sustained release of simultaneous therapeutic substances.•Linezolid is more effecti...

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Bibliographic Details
Published in:	Carbohydrate polymers Vol. 242; p. 116383
Main Authors:	Forero-Doria, Oscar, Polo, Efrain, Marican, Adolfo, Guzmán, Luis, Venegas, Bernardo, Vijayakumar, Sekar, Wehinger, Sergio, Guerrero, Marcelo, Gallego, Jaime, Durán-Lara, Esteban F.
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 15.08.2020
Subjects:	allantoin Animals Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - pharmacology Antibacterial activity bioactive compounds carbon nanotubes Cell Line Cellulose Cellulose - chemistry Cellulose - pharmacology chalcone chromatography crosslinking Drug Liberation drugs Enterococcus faecium - drug effects Fourier transform infrared spectroscopy Hydrogel hydrogels Hydrogels - chemistry Hydrogels - pharmacology Kinetics linezolid Macromolecular Substances - chemistry Macromolecular Substances - pharmacology Mice Microbial Sensitivity Tests Molecular Structure Nanotube Particle Size Rats Rats, Sprague-Dawley resveratrol scanning electron microscopy Spectroscopy, Fourier Transform Infrared Surface Properties Sustained release Temperature therapeutics thermogravimetry tissue repair Wound healing Wound Healing - drug effects Sustained release Antibacterial activity Wound healing Hydrogel Cellulose Nanotube
ISSN:	0144-8617, 1879-1344, 1879-1344
Online Access:	Get full text
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