KLRG1 negatively regulates natural killer cell functions through the Akt pathway in individuals with chronic hepatitis C virus infection

In this study, we demonstrate that killer cell lectin-like receptor subfamily G member 1 (KLRG1), a transmembrane protein preferentially expressed on T cells, is highly expressed on CD56(+) NK cells, which are significantly reduced in their numbers and functions in the peripheral blood of patients w...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of virology Jg. 87; H. 21; S. 11626
Hauptverfasser:	Wang, Jia M, Cheng, Yong Q, Shi, Lei, Ying, Ruo S, Wu, Xiao Y, Li, Guang Y, Moorman, Jonathan P, Yao, Zhi Q
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.11.2013
Schlagworte:	Apoptosis CD56 Antigen - analysis Cell Proliferation Female Hepatitis C, Chronic - immunology Humans Interferon-gamma - secretion Killer Cells, Natural - chemistry Killer Cells, Natural - immunology Lectins, C-Type - metabolism Male Signal Transduction Trans-Activators - metabolism
ISSN:	1098-5514, 1098-5514
Online-Zugang:	Weitere Angaben
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!