Vitamin D Supplements and Prevention of Cancer and Cardiovascular Disease

This article reports the vitamin D portion of a randomized, two-by-two factorial trial of n−3 fatty acids and vitamin D in the prevention of cancer and cardiovascular disease. Vitamin D did not result in a lower incidence of invasive cancer or cardiovascular events than placebo.

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Podrobná bibliografie
Vydáno v:	The New England journal of medicine Ročník 380; číslo 1; s. 33 - 44
Hlavní autoři:	Manson, JoAnn E, Cook, Nancy R, Lee, I-Min, Christen, William, Bassuk, Shari S, Mora, Samia, Gibson, Heike, Gordon, David, Copeland, Trisha, D’Agostino, Denise, Friedenberg, Georgina, Ridge, Claire, Bubes, Vadim, Giovannucci, Edward L, Willett, Walter C, Buring, Julie E
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States Massachusetts Medical Society 03.01.2019
Témata:	Aged Breast cancer Cancer Cardiovascular disease Cardiovascular diseases Cardiovascular Diseases - epidemiology Cardiovascular Diseases - mortality Cardiovascular Diseases - prevention & control Cerebral infarction Colorectal cancer Colorectal carcinoma Death Diabetes Dietary Supplements Disease prevention Double-Blind Method Drug dosages Fatty acids FDA approval Female Follow-Up Studies Humans Hypercalcemia Incidence Invasiveness Male Middle Aged Myocardial infarction Neoplasms - epidemiology Neoplasms - mortality Neoplasms - prevention & control Omega-3 fatty acids Prostate cancer Questionnaires Supplements Treatment Failure Vitamin D Vitamin D - adverse effects Vitamin D - analogs & derivatives Vitamin D - therapeutic use Vitamin D3 Vitamins - adverse effects Vitamins - therapeutic use Womens health United States > US
ISSN:	0028-4793, 1533-4406, 1533-4406
On-line přístup:	Získat plný text
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Popis
Shrnutí:	This article reports the vitamin D portion of a randomized, two-by-two factorial trial of n−3 fatty acids and vitamin D in the prevention of cancer and cardiovascular disease. Vitamin D did not result in a lower incidence of invasive cancer or cardiovascular events than placebo.
Bibliografie:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 ObjectType-Undefined-3
ISSN:	0028-4793 1533-4406 1533-4406
DOI:	10.1056/NEJMoa1809944