Vitamin D Supplements and Prevention of Cancer and Cardiovascular Disease

This article reports the vitamin D portion of a randomized, two-by-two factorial trial of n−3 fatty acids and vitamin D in the prevention of cancer and cardiovascular disease. Vitamin D did not result in a lower incidence of invasive cancer or cardiovascular events than placebo.

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Bibliographic Details
Published in:The New England journal of medicine Vol. 380; no. 1; pp. 33 - 44
Main Authors: Manson, JoAnn E, Cook, Nancy R, Lee, I-Min, Christen, William, Bassuk, Shari S, Mora, Samia, Gibson, Heike, Gordon, David, Copeland, Trisha, D’Agostino, Denise, Friedenberg, Georgina, Ridge, Claire, Bubes, Vadim, Giovannucci, Edward L, Willett, Walter C, Buring, Julie E
Format: Journal Article
Language:English
Published: United States Massachusetts Medical Society 03.01.2019
Subjects:
Aged
Breast cancer
Cancer
Cardiovascular disease
Cardiovascular diseases
Cardiovascular Diseases - epidemiology
Cardiovascular Diseases - mortality
Cardiovascular Diseases - prevention & control
Cerebral infarction
Colorectal cancer
Colorectal carcinoma
Death
Diabetes
Dietary Supplements
Disease prevention
Double-Blind Method
Drug dosages
Fatty acids
FDA approval
Female
Follow-Up Studies
Humans
Hypercalcemia
Incidence
Invasiveness
Male
Middle Aged
Myocardial infarction
Neoplasms - epidemiology
Neoplasms - mortality
Neoplasms - prevention & control
Omega-3 fatty acids
Prostate cancer
Questionnaires
Supplements
Treatment Failure
Vitamin D
Vitamin D - adverse effects
Vitamin D - analogs & derivatives
Vitamin D - therapeutic use
Vitamin D3
Vitamins - adverse effects
Vitamins - therapeutic use
Womens health
United States > US
ISSN:0028-4793, 1533-4406, 1533-4406
Online Access:Get full text
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Description
Summary:This article reports the vitamin D portion of a randomized, two-by-two factorial trial of n−3 fatty acids and vitamin D in the prevention of cancer and cardiovascular disease. Vitamin D did not result in a lower incidence of invasive cancer or cardiovascular events than placebo.
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SourceType-Scholarly Journals-1
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ISSN:0028-4793
1533-4406
1533-4406
DOI:10.1056/NEJMoa1809944