OLGA: fast computation of generation probabilities of B- and T-cell receptor amino acid sequences and motifs

High-throughput sequencing of large immune repertoires has enabled the development of methods to predict the probability of generation by V(D)J recombination of T- and B-cell receptors of any specific nucleotide sequence. These generation probabilities are very non-homogeneous, ranging over 20 order...

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Vydané v:	Bioinformatics (Oxford, England) Ročník 35; číslo 17; s. 2974 - 2981
Hlavní autori:	Sethna, Zachary, Elhanati, Yuval, Callan, Curtis G, Walczak, Aleksandra M, Mora, Thierry
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	England Oxford University Press (OUP) 01.09.2019 Oxford University Press
Predmet:	Biochemistry, Molecular Biology Genomics Life Sciences Original Papers Physics
ISSN:	1367-4803, 1367-4811, 1367-4811
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