OLGA: fast computation of generation probabilities of B- and T-cell receptor amino acid sequences and motifs

High-throughput sequencing of large immune repertoires has enabled the development of methods to predict the probability of generation by V(D)J recombination of T- and B-cell receptors of any specific nucleotide sequence. These generation probabilities are very non-homogeneous, ranging over 20 order...

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Bibliographic Details

Published in:	Bioinformatics (Oxford, England) Vol. 35; no. 17; pp. 2974 - 2981
Main Authors:	Sethna, Zachary, Elhanati, Yuval, Callan, Curtis G, Walczak, Aleksandra M, Mora, Thierry
Format:	Journal Article
Language:	English
Published:	England Oxford University Press (OUP) 01.09.2019 Oxford University Press
Subjects:	Biochemistry, Molecular Biology Genomics Life Sciences Original Papers Physics
ISSN:	1367-4803, 1367-4811, 1367-4811
Online Access:	Get full text
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