Macrophage-targeted, enzyme-triggered fluorescence switch-on system for detection of embolism-vulnerable atherosclerotic plaques

The development of atherosclerotic plaques is a critical step that can result in an arterial embolism. Therefore, detection of these vulnerable plaques is of clinical significance for the diagnosis of atherosclerosis. However, there are few imaging systems able to detect such plaques easily. In this...

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Bibliographic Details
Published in:	Journal of controlled release Vol. 302; pp. 105 - 115
Main Authors:	Narita, Yudai, Shimizu, Kosuke, Ikemoto, Keisuke, Uchino, Ryuji, Kosugi, Mutsumi, Maess, Marten B., Magata, Yasuhiro, Oku, Naoto, Ogawa, Mikako
Format:	Journal Article
Language:	English
Published:	Netherlands 28.05.2019
Subjects:	atherosclerosis cathepsin B embolism fluorescence fluorescent dyes image analysis intravenous injection macrophages phosphatidylserines rabbits Cathepsin B Liposome Fluorescence imaging Atherosclerotic vulnerable plaque Phosphatidylserine Macrophage
ISSN:	0168-3659, 1873-4995, 1873-4995
Online Access:	Get full text
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