Human menstrual blood-derived mesenchymal cells as a cell source of rapid and efficient nuclear reprogramming

Induced pluripotent stem cells (iPSCs) were originally generated by forced ectopic expression of four transcription factors genes-OCT4, KLF4, SOX2, and c-MYC-in fibroblasts. However, the efficiency of iPSCs obtention is extremely low, and reprogramming takes about 20 days. We reasoned that adult cel...

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Veröffentlicht in:	Cell transplantation Jg. 21; H. 10; S. 2215
Hauptverfasser:	de Carvalho Rodrigues, Deivid, Asensi, Karina Dutra, Vairo, Leandro, Azevedo-Pereira, Ricardo Luiz, Silva, Rosane, Rondinelli, Edson, Goldenberg, Regina Coeli, Campos de Carvalho, Antonio Carlos, Urményi, Turán Péter
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States SAGE Publishing 01.01.2012
Schlagworte:	Blood Cells - cytology Blood Cells - metabolism Blood Cells - physiology Cell Culture Techniques - methods Cell Differentiation - physiology Cellular Reprogramming - physiology Female Gene Expression Humans Immunohistochemistry Induced Pluripotent Stem Cells - cytology Induced Pluripotent Stem Cells - metabolism Induced Pluripotent Stem Cells - physiology Menstruation - blood Mesenchymal Stromal Cells - cytology Mesenchymal Stromal Cells - metabolism Mesenchymal Stromal Cells - physiology
ISSN:	1555-3892, 0963-6897, 1555-3892
Online-Zugang:	Volltext
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