Natural Killer Cell-Mediated Cytotoxicity Shapes the Clonal Evolution of B-cell Leukemia

The term cancer immunoediting describes the dual role by which the immune system can suppress and promote tumor growth and is divided into three phases: elimination, equilibrium, and escape. The role of NK cells has mainly been attributed to the elimination phase. Here, we show that NK cells play a...

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Veröffentlicht in:	Cancer immunology research Jg. 13; H. 3; S. 430
Hauptverfasser:	Buri, Michelle C, Shoeb, Mohamed R, Bykov, Aleksandr, Repiscak, Peter, Baik, Hayeon, Dupanovic, Alma, David, Faith O, Kovacic, Boris, Hall-Glenn, Faith, Dopa, Sara, Urbanus, Jos, Sippl, Lisa, Stofner, Susanne, Emminger, Dominik, Cosgrove, Jason, Schinnerl, Dagmar, Poetsch, Anna R, Lehner, Manfred, Koenig, Xaver, Perié, Leïla, Schumacher, Ton N, Gotthardt, Dagmar, Halbritter, Florian, Putz, Eva M
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 04.03.2025
Schlagworte:	Animals Cell Line, Tumor Clonal Evolution - immunology Coculture Techniques Cytotoxicity, Immunologic - immunology Humans Killer Cells, Natural - immunology Killer Cells, Natural - metabolism Leukemia, B-Cell - genetics Leukemia, B-Cell - immunology Leukemia, B-Cell - pathology Mice Mice, Inbred C57BL Tumor Escape
ISSN:	2326-6074, 2326-6074
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