Adjuvant Chemotherapy plus Radiation for Locally Advanced Endometrial Cancer

After a median of nearly 4 years of follow-up, the use of radiotherapy combined with chemotherapy in patients with stage III or IVA endometrial carcinoma was not associated with longer relapse-free survival than the use of chemotherapy alone.

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Podrobná bibliografia
Vydané v:	The New England journal of medicine Ročník 380; číslo 24; s. 2317 - 2326
Hlavní autori:	Matei, Daniela, Filiaci, Virginia, Randall, Marcus E, Mutch, David, Steinhoff, Margaret M, DiSilvestro, Paul A, Moxley, Katherine M, Kim, Yong M, Powell, Matthew A, O’Malley, David M, Spirtos, Nick M, Small, William, Tewari, Krishnansu S, Richards, William E, Nakayama, John, Matulonis, Ursula A, Huang, Helen Q, Miller, David S
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States Massachusetts Medical Society 13.06.2019
Predmet:	Abdomen Adjuvants Adult Aged Aged, 80 and over Antineoplastic Combined Chemotherapy Protocols - therapeutic use Cancer therapies Carcinoma Chemoradiotherapy Chemoradiotherapy, Adjuvant Chemotherapy Chemotherapy, Adjuvant Computer centers Disease-Free Survival Endometrial cancer Endometrial Neoplasms - mortality Endometrial Neoplasms - pathology Endometrial Neoplasms - surgery Endometrial Neoplasms - therapy Endometrium Female Humans Kaplan-Meier Estimate Metastasis Middle Aged Neoplasm Recurrence, Local Neoplasm Staging Neoplasm, Residual Oncology Patients Platinum Prognosis Quality of Life Radiation therapy Recurrence Statistics, Nonparametric Survival Treatment Outcome Uterine cancer Vagina
ISSN:	0028-4793, 1533-4406, 1533-4406
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Popis
Shrnutí:	After a median of nearly 4 years of follow-up, the use of radiotherapy combined with chemotherapy in patients with stage III or IVA endometrial carcinoma was not associated with longer relapse-free survival than the use of chemotherapy alone.
Bibliografia:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 ObjectType-Undefined-3 Address reprint requests to Dr. Matei at the Division of Gynecologic Oncology, Northwestern University, 303 E. Superior St., Lurie 4-107, Chicago, IL 60610, or at daniela.matei@northwestern.edu.
ISSN:	0028-4793 1533-4406 1533-4406
DOI:	10.1056/NEJMoa1813181