A critical assessment of antimicrobial treatment in uncomplicated Salmonella enteritis

The human and veterinary literature on the effect of antimicrobials on the clinical and bacteriological cure in uncomplicated Salmonella gastroenteritis is reviewed. Comparison of data on the efficacy of conventional antimicrobials (chloramphenicol, neomycin, ampicillin, amoxycillin, tetracycline, t...

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Veröffentlicht in:Veterinary microbiology Jg. 73; H. 1; S. 61 - 73
Hauptverfasser: van Duijkeren, E, Houwers, D.J
Format: Journal Article
Sprache:Englisch
Veröffentlicht: Netherlands Elsevier B.V 04.04.2000
Schlagworte:
Aminoglycosides
AMOXICILLIN
Ampicillin/amoxycillin
Animals
Anti-Bacterial Agents
Anti-Bacterial Agents - therapeutic use
Anti-Infective Agents
Anti-Infective Agents - therapeutic use
Anti-Infective Agents, Urinary
Anti-Infective Agents, Urinary - therapeutic use
antibiotics
ANTIMICROBIAL PROPERTIES
ANTIMICROBIALS
ANTIMICROBIANOS
ANTIMICROBIEN
Cattle
Chloramphenicol
Chloramphenicol - therapeutic use
disease course
drug effects
DRUG THERAPY
duration
Efficacy
ENTERITE
ENTERITIS
excretion
Fluoroquinolones
gastroenteritis
Gastroenteritis - drug therapy
Gastroenteritis - veterinary
Humans
NEOMICINA
NEOMYCIN
NEOMYCINE
PENICILINA
PENICILLINE
PENICILLINS
Penicillins - therapeutic use
PROPIEDADES ANTIMICROBIANAS
PROPRIETE ANTIMICROBIENNE
quinolones
SALMONELLA
Salmonella - drug effects
Salmonella Infections, Animal
Salmonella Infections, Animal - drug therapy
Salmonella spp
SULFAMIDE
SULFONAMIDAS
SULPHONAMIDES
TERAPEUTICA MEDICAMENTOSA
TETRACYCLINE
Tetracyclines
therapeutic use
THERAPEUTIQUE MEDICAMENTEUSE
TREATMENT
TRIMETHOPRIM
Trimethoprim/sulfonamide combinations
TRIMETHOPRIME
TRIMETROPINA
veterinary
ZOONOSE
ZOONOSES
ZOONOSIS
Fluoroquinolones
Salmonella spp
Neomycin
Ampicillin/amoxycillin
Efficacy
Trimethoprim/sulfonamide combinations
Zoonosis
Tetracycline
ISSN:0378-1135, 1873-2542
Online-Zugang:Volltext
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Beschreibung
Zusammenfassung:The human and veterinary literature on the effect of antimicrobials on the clinical and bacteriological cure in uncomplicated Salmonella gastroenteritis is reviewed. Comparison of data on the efficacy of conventional antimicrobials (chloramphenicol, neomycin, ampicillin, amoxycillin, tetracycline, trimethoprim/sulfonamide combinations) and the newer fluoroquinolones indicate that quinolones may shorten the course of clinical disease in contrast to the conventional antimicrobials. Postconvalescent excretion of Salmonella was not affected by the conventional antimicrobials whereas the data on the fluoroquinolones in this respect are conflicting. The fluoroquinolones are the drugs of choice in human medicine for severe Salmonella infections and for the elimination of the carrier state. These drugs have not been evaluated in this respect in veterinary medicine. Well designed prospective placebo-controlled studies regarding the effect of antimicrobials, especially the fluoroquinolones, on the clinical cure and the postconvalescent shedding of Salmonella in animals are imperative to develop optimal therapeutic strategies.
Bibliographie:Q03
2000004412
ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ObjectType-Article-1
ObjectType-Feature-2
ObjectType-Review-3
ISSN:0378-1135
1873-2542
DOI:10.1016/S0378-1135(00)00156-5