Derivation and validation of cutoffs for clinical use of cell cycle arrest biomarkers

Acute kidney injury (AKI) remains a deadly condition. Tissue inhibitor of metalloproteinases (TIMP)-2 and insulin-like growth factor binding protein (IGFBP)7 are two recently discovered urinary biomarkers for AKI. We now report on the development, and diagnostic accuracy of two clinical cutoffs for...

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Vydáno v:	Nephrology, dialysis, transplantation Ročník 29; číslo 11; s. 2054
Hlavní autoři:	Hoste, Eric A J, McCullough, Peter A, Kashani, Kianoush, Chawla, Lakhmir S, Joannidis, Michael, Shaw, Andrew D, Feldkamp, Thorsten, Uettwiller-Geiger, Denise L, McCarthy, Paul, Shi, Jing, Walker, Michael G, Kellum, John A
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	England 01.11.2014
Témata:	Acute Kidney Injury - pathology Acute Kidney Injury - urine Aged Biomarkers - urine Cell Cycle Checkpoints - physiology Female Follow-Up Studies Humans Insulin-Like Growth Factor Binding Proteins - urine Male Middle Aged Predictive Value of Tests ROC Curve Tissue Inhibitor of Metalloproteinase-2 - urine insulin-like growth factor binding protein (IGFBP)7 and tissue inhibitor of metalloproteinases (TIMP)-2 acute kidney injury acute renal failure sensitivity and specificity (MeSH) biomarkers
ISSN:	1460-2385, 1460-2385
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