Fast-SNP: a fast matrix pre-processing algorithm for efficient loopless flux optimization of metabolic models

Motivation: Computation of steady-state flux solutions in large metabolic models is routinely performed using flux balance analysis based on a simple LP (Linear Programming) formulation. A minimal requirement for thermodynamic feasibility of the flux solution is the absence of internal loops, which...

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Bibliographic Details

Published in:	Bioinformatics (Oxford, England) Vol. 32; no. 24; pp. 3807 - 3814
Main Authors:	Saa, Pedro A., Nielsen, Lars K.
Format:	Journal Article
Language:	English
Published:	England Oxford University Press 15.12.2016
Subjects:	Algorithms Computational Biology - methods Metabolic Networks and Pathways Models, Biological Original Papers Programming, Linear Software
ISSN:	1367-4803, 1367-4811, 1367-4811
Online Access:	Get full text
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