Bioactive decellularized cardiac extracellular matrix-based hydrogel as a sustained-release platform for human adipose tissue-derived stromal cell-secreted factors

The administration of trophic factors (TFs) released by mesenchymal stromal cells (MSCs) as therapy for cardiovascular diseases requires a delivery vehicle capable of binding and releasing the TF in a sustained manner. We hypothesized that hydrogels derived from cardiac decellularized extracellular...

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Bibliographic Details
Published in:	Biomedical materials (Bristol) Vol. 16; no. 2; p. 025022
Main Authors:	Liguori, Tácia Tavares Aquinas, Liguori, Gabriel Romero, van Dongen, Joris A, Moreira, Luiz Felipe Pinho, Harmsen, Martin Conrad
Format:	Journal Article
Language:	English
Published:	England 01.03.2021
Subjects:	Adipose Tissue - metabolism Animals Cell Proliferation Culture Media, Conditioned Cytokines - metabolism Decellularized Extracellular Matrix - chemistry Delayed-Action Preparations Extracellular Matrix - metabolism Heart Heart Ventricles - metabolism Human Umbilical Vein Endothelial Cells Humans Hydrogels - chemistry Kinetics Mesenchymal Stem Cells - cytology Regeneration Secretome Stromal Cells - metabolism Swine Vascular Endothelial Growth Factor A - metabolism
ISSN:	1748-605X, 1748-605X
Online Access:	Get more information
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