Advancements in medical research: Exploring Fourier Transform Infrared (FTIR) spectroscopy for tissue, cell, and hair sample analysis

Background Fourier Transform Infrared (FTIR) spectroscopy has emerged as a powerful analytical tool in medical research, offering non‐invasive and precise examination of the molecular composition of biological samples. The primary objective of this review is to underscore the benefits of FTIR spectr...

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Vydáno v:Skin research and technology Ročník 30; číslo 6; s. e13733 - n/a
Hlavní autoři: Al‐Kelani, Madeha, Buthelezi, Ntandoyenkosi
Médium: Journal Article
Jazyk:angličtina
Vydáno: England John Wiley & Sons, Inc 01.06.2024
John Wiley and Sons Inc
Témata:
Biological properties
Biological samples
Biomedical Research - methods
Chemical composition
Chemical fingerprinting
Counterfeit
Data interpretation
Fourier analysis
Fourier transforms
FTIR spectroscopy
Hair
Hair - chemistry
hair samples and wavenumbers
Humans
Infrared analysis
Infrared spectroscopy
Invited Review
Literature reviews
Medical research
Sample preparation
Skin - chemistry
Skin - pathology
Spectroscopy
Spectroscopy, Fourier Transform Infrared - methods
Spectrum analysis
stem cells
tissue
stem cells
tissue
hair samples and wavenumbers
FTIR spectroscopy
ISSN:0909-752X, 1600-0846, 1600-0846
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Popis
Shrnutí:Background Fourier Transform Infrared (FTIR) spectroscopy has emerged as a powerful analytical tool in medical research, offering non‐invasive and precise examination of the molecular composition of biological samples. The primary objective of this review is to underscore the benefits of FTIR spectroscopy in medicinal research, emphasizing its ability to delineate molecular fingerprints and assist in the identification of biochemical structures and key peaks in biological samples. Methods This review comprehensively explores the diverse applications of FTIR spectroscopy in medical investigations, with a specific focus on its utility in analyzing tissue, cells, and hair samples. Various sources, including Google Scholar, PubMed, WorledCat and Scopus, were utilized to conduct this comprehensive literature review. Results Recent advancements showcase the versatility of FTIR spectroscopy in elucidating cellular and molecular processes, facilitating disease diagnostics, and enabling treatment monitoring. Notably, FTIR spectroscopy has found significant utility in clinical assessment, particularly in screening counterfeit medicines, owing to its user‐friendly operation and minimal sample preparation requirements. Furthermore, customs officials can leverage this technique for preliminary analysis of suspicious samples. Conclusion This review aims to bridge a gap in the literature and serve as a valuable resource for future research endeavors in FTIR spectroscopy within the medical domain. Additionally, it presents fundamental concepts of FTIR spectroscopy and spectral data interpretation, highlighting its utility as a tool for molecular analysis using Mid‐Infrared (MIR) radiation.
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ISSN:0909-752X
1600-0846
1600-0846
DOI:10.1111/srt.13733