Advancements in medical research: Exploring Fourier Transform Infrared (FTIR) spectroscopy for tissue, cell, and hair sample analysis
Background Fourier Transform Infrared (FTIR) spectroscopy has emerged as a powerful analytical tool in medical research, offering non‐invasive and precise examination of the molecular composition of biological samples. The primary objective of this review is to underscore the benefits of FTIR spectr...
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| Vydáno v: | Skin research and technology Ročník 30; číslo 6; s. e13733 - n/a |
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| Hlavní autoři: | , |
| Médium: | Journal Article |
| Jazyk: | angličtina |
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England
John Wiley & Sons, Inc
01.06.2024
John Wiley and Sons Inc |
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| ISSN: | 0909-752X, 1600-0846, 1600-0846 |
| On-line přístup: | Získat plný text |
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| Abstract | Background
Fourier Transform Infrared (FTIR) spectroscopy has emerged as a powerful analytical tool in medical research, offering non‐invasive and precise examination of the molecular composition of biological samples. The primary objective of this review is to underscore the benefits of FTIR spectroscopy in medicinal research, emphasizing its ability to delineate molecular fingerprints and assist in the identification of biochemical structures and key peaks in biological samples.
Methods
This review comprehensively explores the diverse applications of FTIR spectroscopy in medical investigations, with a specific focus on its utility in analyzing tissue, cells, and hair samples. Various sources, including Google Scholar, PubMed, WorledCat and Scopus, were utilized to conduct this comprehensive literature review.
Results
Recent advancements showcase the versatility of FTIR spectroscopy in elucidating cellular and molecular processes, facilitating disease diagnostics, and enabling treatment monitoring. Notably, FTIR spectroscopy has found significant utility in clinical assessment, particularly in screening counterfeit medicines, owing to its user‐friendly operation and minimal sample preparation requirements. Furthermore, customs officials can leverage this technique for preliminary analysis of suspicious samples.
Conclusion
This review aims to bridge a gap in the literature and serve as a valuable resource for future research endeavors in FTIR spectroscopy within the medical domain. Additionally, it presents fundamental concepts of FTIR spectroscopy and spectral data interpretation, highlighting its utility as a tool for molecular analysis using Mid‐Infrared (MIR) radiation. |
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| AbstractList | Fourier Transform Infrared (FTIR) spectroscopy has emerged as a powerful analytical tool in medical research, offering non-invasive and precise examination of the molecular composition of biological samples. The primary objective of this review is to underscore the benefits of FTIR spectroscopy in medicinal research, emphasizing its ability to delineate molecular fingerprints and assist in the identification of biochemical structures and key peaks in biological samples.
This review comprehensively explores the diverse applications of FTIR spectroscopy in medical investigations, with a specific focus on its utility in analyzing tissue, cells, and hair samples. Various sources, including Google Scholar, PubMed, WorledCat and Scopus, were utilized to conduct this comprehensive literature review.
Recent advancements showcase the versatility of FTIR spectroscopy in elucidating cellular and molecular processes, facilitating disease diagnostics, and enabling treatment monitoring. Notably, FTIR spectroscopy has found significant utility in clinical assessment, particularly in screening counterfeit medicines, owing to its user-friendly operation and minimal sample preparation requirements. Furthermore, customs officials can leverage this technique for preliminary analysis of suspicious samples.
This review aims to bridge a gap in the literature and serve as a valuable resource for future research endeavors in FTIR spectroscopy within the medical domain. Additionally, it presents fundamental concepts of FTIR spectroscopy and spectral data interpretation, highlighting its utility as a tool for molecular analysis using Mid-Infrared (MIR) radiation. Background Fourier Transform Infrared (FTIR) spectroscopy has emerged as a powerful analytical tool in medical research, offering non‐invasive and precise examination of the molecular composition of biological samples. The primary objective of this review is to underscore the benefits of FTIR spectroscopy in medicinal research, emphasizing its ability to delineate molecular fingerprints and assist in the identification of biochemical structures and key peaks in biological samples. Methods This review comprehensively explores the diverse applications of FTIR spectroscopy in medical investigations, with a specific focus on its utility in analyzing tissue, cells, and hair samples. Various sources, including Google Scholar, PubMed, WorledCat and Scopus, were utilized to conduct this comprehensive literature review. Results Recent advancements showcase the versatility of FTIR spectroscopy in elucidating cellular and molecular processes, facilitating disease diagnostics, and enabling treatment monitoring. Notably, FTIR spectroscopy has found significant utility in clinical assessment, particularly in screening counterfeit medicines, owing to its user‐friendly operation and minimal sample preparation requirements. Furthermore, customs officials can leverage this technique for preliminary analysis of suspicious samples. Conclusion This review aims to bridge a gap in the literature and serve as a valuable resource for future research endeavors in FTIR spectroscopy within the medical domain. Additionally, it presents fundamental concepts of FTIR spectroscopy and spectral data interpretation, highlighting its utility as a tool for molecular analysis using Mid‐Infrared (MIR) radiation. Background Fourier Transform Infrared (FTIR) spectroscopy has emerged as a powerful analytical tool in medical research, offering non‐invasive and precise examination of the molecular composition of biological samples. The primary objective of this review is to underscore the benefits of FTIR spectroscopy in medicinal research, emphasizing its ability to delineate molecular fingerprints and assist in the identification of biochemical structures and key peaks in biological samples. Methods This review comprehensively explores the diverse applications of FTIR spectroscopy in medical investigations, with a specific focus on its utility in analyzing tissue, cells, and hair samples. Various sources, including Google Scholar, PubMed, WorledCat and Scopus, were utilized to conduct this comprehensive literature review. Results Recent advancements showcase the versatility of FTIR spectroscopy in elucidating cellular and molecular processes, facilitating disease diagnostics, and enabling treatment monitoring. Notably, FTIR spectroscopy has found significant utility in clinical assessment, particularly in screening counterfeit medicines, owing to its user‐friendly operation and minimal sample preparation requirements. Furthermore, customs officials can leverage this technique for preliminary analysis of suspicious samples. Conclusion This review aims to bridge a gap in the literature and serve as a valuable resource for future research endeavors in FTIR spectroscopy within the medical domain. Additionally, it presents fundamental concepts of FTIR spectroscopy and spectral data interpretation, highlighting its utility as a tool for molecular analysis using Mid‐Infrared (MIR) radiation. Fourier Transform Infrared (FTIR) spectroscopy has emerged as a powerful analytical tool in medical research, offering non-invasive and precise examination of the molecular composition of biological samples. The primary objective of this review is to underscore the benefits of FTIR spectroscopy in medicinal research, emphasizing its ability to delineate molecular fingerprints and assist in the identification of biochemical structures and key peaks in biological samples.BACKGROUNDFourier Transform Infrared (FTIR) spectroscopy has emerged as a powerful analytical tool in medical research, offering non-invasive and precise examination of the molecular composition of biological samples. The primary objective of this review is to underscore the benefits of FTIR spectroscopy in medicinal research, emphasizing its ability to delineate molecular fingerprints and assist in the identification of biochemical structures and key peaks in biological samples.This review comprehensively explores the diverse applications of FTIR spectroscopy in medical investigations, with a specific focus on its utility in analyzing tissue, cells, and hair samples. Various sources, including Google Scholar, PubMed, WorledCat and Scopus, were utilized to conduct this comprehensive literature review.METHODSThis review comprehensively explores the diverse applications of FTIR spectroscopy in medical investigations, with a specific focus on its utility in analyzing tissue, cells, and hair samples. Various sources, including Google Scholar, PubMed, WorledCat and Scopus, were utilized to conduct this comprehensive literature review.Recent advancements showcase the versatility of FTIR spectroscopy in elucidating cellular and molecular processes, facilitating disease diagnostics, and enabling treatment monitoring. Notably, FTIR spectroscopy has found significant utility in clinical assessment, particularly in screening counterfeit medicines, owing to its user-friendly operation and minimal sample preparation requirements. Furthermore, customs officials can leverage this technique for preliminary analysis of suspicious samples.RESULTSRecent advancements showcase the versatility of FTIR spectroscopy in elucidating cellular and molecular processes, facilitating disease diagnostics, and enabling treatment monitoring. Notably, FTIR spectroscopy has found significant utility in clinical assessment, particularly in screening counterfeit medicines, owing to its user-friendly operation and minimal sample preparation requirements. Furthermore, customs officials can leverage this technique for preliminary analysis of suspicious samples.This review aims to bridge a gap in the literature and serve as a valuable resource for future research endeavors in FTIR spectroscopy within the medical domain. Additionally, it presents fundamental concepts of FTIR spectroscopy and spectral data interpretation, highlighting its utility as a tool for molecular analysis using Mid-Infrared (MIR) radiation.CONCLUSIONThis review aims to bridge a gap in the literature and serve as a valuable resource for future research endeavors in FTIR spectroscopy within the medical domain. Additionally, it presents fundamental concepts of FTIR spectroscopy and spectral data interpretation, highlighting its utility as a tool for molecular analysis using Mid-Infrared (MIR) radiation. |
| Author | Al‐Kelani, Madeha Buthelezi, Ntandoyenkosi |
| AuthorAffiliation | 1 Hair and Skin Research Laboratory Division of Dermatology Groote Schuur Hospital Cape Town South Africa 2 Faculty of Health Sciences University of Cape Town Cape Town South Africa |
| AuthorAffiliation_xml | – name: 2 Faculty of Health Sciences University of Cape Town Cape Town South Africa – name: 1 Hair and Skin Research Laboratory Division of Dermatology Groote Schuur Hospital Cape Town South Africa |
| Author_xml | – sequence: 1 givenname: Madeha orcidid: 0000-0001-9060-792X surname: Al‐Kelani fullname: Al‐Kelani, Madeha email: alkmad001@myuct.ac.za organization: University of Cape Town – sequence: 2 givenname: Ntandoyenkosi surname: Buthelezi fullname: Buthelezi, Ntandoyenkosi organization: University of Cape Town |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/38887131$$D View this record in MEDLINE/PubMed |
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| Keywords | stem cells tissue hair samples and wavenumbers FTIR spectroscopy |
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Fourier Transform Infrared (FTIR) spectroscopy has emerged as a powerful analytical tool in medical research, offering non‐invasive and precise... Fourier Transform Infrared (FTIR) spectroscopy has emerged as a powerful analytical tool in medical research, offering non-invasive and precise examination of... Background Fourier Transform Infrared (FTIR) spectroscopy has emerged as a powerful analytical tool in medical research, offering non‐invasive and precise... |
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| SubjectTerms | Biological properties Biological samples Biomedical Research - methods Chemical composition Chemical fingerprinting Counterfeit Data interpretation Fourier analysis Fourier transforms FTIR spectroscopy Hair Hair - chemistry hair samples and wavenumbers Humans Infrared analysis Infrared spectroscopy Invited Review Literature reviews Medical research Sample preparation Skin - chemistry Skin - pathology Spectroscopy Spectroscopy, Fourier Transform Infrared - methods Spectrum analysis stem cells tissue |
| Title | Advancements in medical research: Exploring Fourier Transform Infrared (FTIR) spectroscopy for tissue, cell, and hair sample analysis |
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