Combined Anastrozole and Antiplatelet Therapy Treatment Differentially Promotes Breast Cancer Cell Survival

Thromboembolic disorders are the second leading cause of death in breast cancer. Antiplatelet therapy combined with cancer therapy is a potential treatment strategy against cancer-associated thromboembolic disorders; however, the efficacy of such dual treatment has not been established. This study r...

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Bibliographic Details
Published in:	Microscopy and microanalysis Vol. 26; no. 3; pp. 497 - 508
Main Authors:	Xulu, Kutlwano, Duarte, Raquel, Augustine, Tanya
Format:	Journal Article
Language:	English
Published:	New York, USA Cambridge University Press 01.06.2020 Oxford University Press
Subjects:	Anastrozole Anastrozole - pharmacology Annexin A5 Apoptosis Aspirin Biological Applications Biotechnology Breast cancer Breast Neoplasms - drug therapy Cancer therapies Cell death Cell growth Cell Line, Tumor Cell survival Cell Survival - drug effects Clopidogrel Combined treatment Cytochrome Cytotoxicity Disorders Enzymes Flow cytometry Humans Iodides L-Lactate dehydrogenase Lactate dehydrogenase Lactic acid MCF-7 Cells Mortality Necrosis Penicillin Phenotypes Phosphatidylserine Plasma Platelet Aggregation Inhibitors - pharmacology Propidium Propidium iodide Pseudopodia Scanning electron microscopy Statistical analysis Survival Therapeutic applications Therapy Thromboembolism Thrombosis Toxicity Tumor cell lines Tumors South Africa breast cancer cell survival antiplatelet therapy anastrozole
ISSN:	1431-9276, 1435-8115, 1435-8115
Online Access:	Get full text
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