RET gene rearrangements occur in a subset of pancreatic acinar cell carcinomas

Pancreatic acinar cell carcinoma is relatively rare (1 to 2% of pancreatic malignancies) but may be under-recognized. In contrast to pancreatic ductal adenocarcinoma, most acinar cell carcinomas lack mutations in KRAS , DPC , CDKN2A or TP53 , but appear to have a high incidence of gene rearrangement...

Celý popis