CircRNA in cancer: Fundamental mechanism and clinical potential

Circular RNAs (CircRNAs) are a class of single-stranded noncoding RNAs that are formed in a circular conformation via non-canonical splicing or back-splicing events. Aberrant expressions of many circRNAs are observed in diverse cancers, indicating their crucial roles in tumorigenesis and tumor devel...

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Bibliographic Details
Published in:	Cancer letters Vol. 505; pp. 49 - 57
Main Authors:	Chen, Liang, Shan, Ge
Format:	Journal Article
Language:	English
Published:	Ireland Elsevier B.V 01.05.2021 Elsevier Limited
Subjects:	Back-splicing Binding sites Bioinformatics Biosynthesis By products Cancer Cell cycle Circular RNA Competition Conformation Dysregulation Gene expression Genomes MicroRNAs miRNA sponge Molecular modelling Proteins RNA binding proteins Tumorigenesis Dysregulation miRNA sponge Circular RNA Back-splicing RNA binding proteins
ISSN:	0304-3835, 1872-7980, 1872-7980
Online Access:	Get full text
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