Elucidating the 3D Structure of a Surface Membrane Antigen from Trypanosoma cruzi as a Serodiagnostic Biomarker of Chagas Disease

Chagas disease (CD) is a vector-borne parasitosis, caused by the protozoan parasite Trypanosoma cruzi, that affects millions of people worldwide. Although endemic in South America, CD is emerging throughout the world due to climate change and increased immigratory flux of infected people to non-ende...

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Veröffentlicht in:	Vaccines (Basel) Jg. 10; H. 1; S. 71
Hauptverfasser:	Di Pisa, Flavio, De Benedetti, Stefano, Fassi, Enrico Mario Alessandro, Bombaci, Mauro, Grifantini, Renata, Musicò, Angelo, Frigerio, Roberto, Pontillo, Angela, Rigo, Cinzia, Abelli, Sandra, Grande, Romualdo, Zanchetta, Nadia, Mileto, Davide, Mancon, Alessandro, Rizzo, Alberto, Gori, Alessandro, Cretich, Marina, Colombo, Giorgio, Bolognesi, Martino, Gourlay, Louise Jane
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Switzerland MDPI AG 03.01.2022 MDPI
Schlagworte:	Antibodies Antigens Asymptomatic Biomarkers Chagas disease Climate change Cloning Crystal structure Crystallization Diagnostic systems Epitopes Immunogenicity Immunology in silico epitope mapping Infections Membranes neglected tropical disease Parasites Parasitic diseases Pathogens peptide microarray Peptides Polyclonal antibodies Proteins structural vaccinology Trypanosoma cruzi Vector-borne diseases United Kingdom > UK United States > US in silico epitope mapping structural vaccinology Chagas disease neglected tropical disease peptide microarray immunodiagnostics Trypanosoma cruzi
ISSN:	2076-393X, 2076-393X
Online-Zugang:	Volltext
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