Serum coding and non‐coding RNAs as biomarkers of NAFLD and fibrosis severity

Background & Aims In patients with non‐alcoholic fatty liver disease (NAFLD), liver biopsy is the gold standard to detect non‐alcoholic steatohepatitis (NASH) and stage liver fibrosis. We aimed to identify differentially expressed mRNAs and non‐coding RNAs in serum samples of biopsy‐diagnosed mi...

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Veröffentlicht in:	Liver international Jg. 39; H. 9; S. 1742 - 1754
Hauptverfasser:	Di Mauro, Stefania, Scamporrino, Alessandra, Petta, Salvatore, Urbano, Francesca, Filippello, Agnese, Ragusa, Marco, Di Martino, Maria T., Scionti, Francesca, Grimaudo, Stefania, Pipitone, Rosaria M., Privitera, Graziella, Di Pino, Antonino, Scicali, Roberto, Valenti, Luca, Dongiovanni, Paola, Fracanzani, Anna, Rabuazzo, Agata M., Craxì, Antonio, Purrello, Michele, Purrello, Francesco, Piro, Salvatore
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Wiley Subscription Services, Inc 01.09.2019 John Wiley and Sons Inc
Schlagworte:	Adult Biomarkers Biomarkers - blood Biopsy Cohort Studies Control Diagnostic systems Disease Progression DNA microarrays Extracellular levels Fatty liver Female Fibrosis Gene expression Gene Expression Profiling Hepatocytes Humans Intracellular liquid‐biopsy Liver Liver - enzymology Liver - pathology Liver Cirrhosis - blood Liver Cirrhosis - diagnosis Liver Cirrhosis - pathology Liver diseases Male Metabolic Liver Disease Middle Aged Molecular modelling NAFLD NASH Non-alcoholic Fatty Liver Disease - blood Non-alcoholic Fatty Liver Disease - diagnosis Non-alcoholic Fatty Liver Disease - pathology Palmitic acid Predictive Value of Tests RNA, Untranslated - blood RNAs ROC Curve Severity of Illness Index Transcription RNAs NAFLD liquid-biopsy fibrosis NASH
ISSN:	1478-3223, 1478-3231, 1478-3231
Online-Zugang:	Volltext
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