Improved repeatability of dynamic contrast‐enhanced MRI using the complex MRI signal to derive arterial input functions: a test‐retest study in prostate cancer patients

Purpose The arterial input function (AIF) is a major source of uncertainty in tracer kinetic (TK) analysis of dynamic contrast‐enhanced (DCE)‐MRI data. The aim of this study was to investigate the repeatability of AIFs extracted from the complex signal and of the resulting TK parameters in prostate...

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Bibliographic Details
Published in:	Magnetic resonance in medicine Vol. 81; no. 5; pp. 3358 - 3369
Main Authors:	Klawer, Edzo M.E., van Houdt, Petra J., Simonis, Frank F.J., van den Berg, Cornelis A.T., Pos, Floris J., Heijmink, Stijn W.T.P.J., Isebaert, Sofie, Haustermans, Karin, van der Heide, Uulke A.
Format:	Journal Article
Language:	English
Published:	United States Wiley Subscription Services, Inc 01.05.2019 John Wiley and Sons Inc
Subjects:	Aged Algorithms arterial input function Biopsy Coefficient of variation complex signal Computer Simulation Contrast Media - administration & dosage Data acquisition dynamic contrast‐enhanced MRI Full Papers—Computer Processing and Modeling Humans Image Interpretation, Computer-Assisted - methods Image Processing, Computer-Assisted Kinetics Magnetic Resonance Imaging Male Middle Aged Models, Statistical Patients Prostate cancer Prostatic Neoplasms - diagnostic imaging Quantitative analysis repeatability Reproducibility Reproducibility of Results tracer kinetic analysis repeatability prostate cancer complex signal arterial input function tracer kinetic analysis dynamic contrast-enhanced MRI
ISSN:	0740-3194, 1522-2594, 1522-2594
Online Access:	Get full text
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