Supporting measurements or more averages? How to quantify cerebral blood flow most reliably in 5 minutes by arterial spin labeling

Purpose To determine whether sacrificing part of the scan time of pseudo‐continuous arterial spin labeling (PCASL) for measurement of the labeling efficiency and blood T1 is beneficial in terms of CBF quantification reliability. Methods In a simulation framework, 5‐minute scan protocols with differe...

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Bibliographic Details
Published in:	Magnetic resonance in medicine Vol. 84; no. 5; pp. 2523 - 2536
Main Authors:	Bladt, Piet, van Osch, Matthias J. P., Clement, Patricia, Achten, Eric, Sijbers, Jan, den Dekker, Arnold J.
Format:	Journal Article
Language:	English
Published:	United States Wiley Subscription Services, Inc 01.11.2020 John Wiley and Sons Inc
Subjects:	absolute quantification Arteries Blood flow Brain - diagnostic imaging Cerebral blood flow Cerebrovascular Circulation Data acquisition Efficiency Full Papers—Imaging Methodology Ground truth Humans Labeling labeling efficiency longitudinal relaxation time of blood Magnetic Resonance Angiography Population (statistical) Population distribution Population statistics pseudo‐continuous arterial spin labeling Reproducibility of Results Spin labeling Spin Labels Variability labeling efficiency cerebral blood flow absolute quantification pseudo-continuous arterial spin labeling longitudinal relaxation time of blood
ISSN:	0740-3194, 1522-2594, 1522-2594
Online Access:	Get full text
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