Aspirin and clopidogrel high on‐treatment platelet reactivity and genetic predictors in peripheral arterial disease

Objectives Our aims were to examine the prevalence and genetic predictors of aspirin and clopidogrel high on‐treatment platelet reactivity (HoTPR), and associated adverse cardiovascular outcomes in patients with peripheral arterial disease (PAD). Background The association of aspirin and clopidogrel...

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Bibliographic Details
Published in:	Catheterization and cardiovascular interventions Vol. 91; no. 7; pp. 1308 - 1317
Main Authors:	Yeo, Khung‐Keong, Armstrong, Ehrin J., López, Javier E., Chen, Debbie C., Westin, Gregory G., Li, Chin‐Shang, Anderson, David, Hua, Amy, Singapuri, Anil, Amsterdam, Ezra A., Chiamvimonvat, Nipavan, Laird, John R.
Format:	Journal Article
Language:	English
Published:	United States Wiley Subscription Services, Inc 01.06.2018
Subjects:	Adult Aged Aged, 80 and over Amputation, Surgical Angiography antiplatelet therapy Arteries Aryldialkylphosphatase - genetics Arylesterase Aspirin Aspirin - adverse effects Aspirin - therapeutic use California - epidemiology Cardiovascular diseases Cerebral infarction Clinical outcomes Clopidogrel Clopidogrel - adverse effects Clopidogrel - therapeutic use Drug Resistance - genetics Drug Therapy, Combination Female genetics Group III Phospholipases A2 - genetics Health risk assessment Humans Limb Salvage Male Middle Aged Myocardial infarction Myocardial Infarction - epidemiology Paraoxonase Patients peripheral arterial disease Peripheral Arterial Disease - diagnosis Peripheral Arterial Disease - drug therapy Peripheral Arterial Disease - epidemiology Peripheral Arterial Disease - genetics Phospholipase A2 Platelet Aggregation Inhibitors - adverse effects Platelet Aggregation Inhibitors - therapeutic use Platelet Function Tests Platelets Polymorphism, Single Nucleotide Prospective Studies Risk Factors Single-nucleotide polymorphism Stroke - epidemiology Time Factors Treatment Outcome California peripheral arterial disease genetics antiplatelet therapy
ISSN:	1522-1946, 1522-726X, 1522-726X
Online Access:	Get full text
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