The utility of P53 immunohistochemistry in the diagnosis of Barrett's oesophagus with indefinite for dysplasia

Aims Barrett's oesophagus with indefinite for dysplasia (BE‐IND) is a subjective diagnosis with a low interobserver agreement (IOA) among pathologists and uncertain clinical implications. This study aimed to assess the utility of p53 immunohistochemistry (p53‐IHC) in assessing BE‐IND specimens....

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Veröffentlicht in:	Histopathology Jg. 80; H. 7; S. 1081 - 1090
Hauptverfasser:	Januszewicz, Wladyslaw, Pilonis, Nastazja D, Sawas, Tarek, Phillips, Richard, O'Donovan, Maria, Miremadi, Ahmad, Malhotra, Shalini, Tripathi, Monika, Blasko, Adrienn, Katzka, David A, Fitzgerald, Rebecca C, Pietro, Massimiliano
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England Wiley Subscription Services, Inc 01.06.2022 John Wiley and Sons Inc
Schlagworte:	Barrett's esophagus biomarkers Biopsy clinical pathology Diagnosis Dysplasia Immunohistochemistry observer variations oesophageal neoplasms Original p53 Protein oesophageal neoplasms clinical pathology observer variations biomarkers
ISSN:	0309-0167, 1365-2559, 1365-2559
Online-Zugang:	Volltext
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