Complement activation in polycystic ovary syndrome occurs in the postprandial and fasted state and is influenced by obesity and insulin sensitivity

Objective Polycystic ovary syndrome (PCOS) is associated with metabolic risk. Complement proteins regulate inflammation and lipid clearance but their role in PCOS‐associated metabolic risk is unclear. We sought to establish whether the complement system is activated in PCOS in the fasting and postpr...

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Vydáno v:	Clinical endocrinology (Oxford) Ročník 94; číslo 1; s. 74 - 84
Hlavní autoři:	Lewis, Ruth D., Narayanaswamy, Anil K., Farewell, Daniel, Rees, Dafydd Aled
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	England Wiley Subscription Services, Inc 01.01.2021 John Wiley and Sons Inc
Témata:	Complement activation Complement component C3 Complement component C4 Complement component C5 Complement component C5a Complement factor H complement system proteins Fasting Insulin Insulin resistance Laboratory testing Metabolism Obesity Original Ovaries Polycystic ovary syndrome Properdin complement system proteins insulin resistance obesity polycystic ovary syndrome
ISSN:	0300-0664, 1365-2265, 1365-2265
On-line přístup:	Získat plný text
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