Genome-wide analysis of the FOXA1 transcriptional regulatory network identifies super enhancer associated LncRNAs in tamoxifen resistance

Breast cancer is the leading cause of death in female cancers, and what’s worse, tamoxifen resistance occurs in almost 30% breast cancer patients and has seriously attenuated the therapeutic effect. It is widely studied that epigenetic regulation has played important role in the development of tamox...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Frontiers in genetics Jg. 13; S. 992444
Hauptverfasser:	Zhang, Xiulei, Zhang, Qian, Liu, Guangzhi
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Frontiers Media S.A 20.09.2022
Schlagworte:	ATP1A1-AS1 breast cancer FoxA1 Genetics super enhancer tamoxifen resistance
ISSN:	1664-8021, 1664-8021
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!