RNAcentral: a comprehensive database of non-coding RNA sequences

RNAcentral is a database of non-coding RNA (ncRNA) sequences that aggregates data from specialised ncRNA resources and provides a single entry point for accessing ncRNA sequences of all ncRNA types from all organisms. Since its launch in 2014, RNAcentral has integrated twelve new resources, taking t...

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Veröffentlicht in:Nucleic acids research Jg. 45; H. D1; S. D128 - D134
Hauptverfasser: Petrov, Anton I, Kay, Simon J E, Kalvari, Ioanna, Howe, Kevin L, Gray, Kristian A, Bruford, Elspeth A, Kersey, Paul J, Cochrane, Guy, Finn, Robert D, Bateman, Alex, Kozomara, Ana, Griffiths-Jones, Sam, Frankish, Adam, Zwieb, Christian W, Lau, Britney Y, Williams, Kelly P, Chan, Patricia P, Lowe, Todd M, Cannone, Jamie J, Gutell, Robin, Machnicka, Magdalena A, Bujnicki, Janusz M, Yoshihama, Maki, Kenmochi, Naoya, Chai, Benli, Cole, James R, Szymanski, Maciej, Karlowski, Wojciech M, Wood, Valerie, Huala, Eva, Berardini, Tanya Z, Zhao, Yi, Chen, Runsheng, Zhu, Weimin, Paraskevopoulou, Maria D, Vlachos, Ioannis S, Hatzigeorgiou, Artemis G, Ma, Lina, Zhang, Zhang, Puetz, Joern, Stadler, Peter F, McDonald, Daniel, Basu, Siddhartha, Fey, Petra, Engel, Stacia R, Cherry, J Michael, Volders, Pieter-Jan, Mestdagh, Pieter, Wower, Jacek, Clark, Michael B, Quek, Xiu Cheng, Dinger, Marcel E
Format: Journal Article
Sprache:Englisch
Veröffentlicht: England Oxford University Press 04.01.2017
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ISSN:0305-1048, 1362-4962, 1362-4962
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Abstract RNAcentral is a database of non-coding RNA (ncRNA) sequences that aggregates data from specialised ncRNA resources and provides a single entry point for accessing ncRNA sequences of all ncRNA types from all organisms. Since its launch in 2014, RNAcentral has integrated twelve new resources, taking the total number of collaborating database to 22, and began importing new types of data, such as modified nucleotides from MODOMICS and PDB. We created new species-specific identifiers that refer to unique RNA sequences within a context of single species. The website has been subject to continuous improvements focusing on text and sequence similarity searches as well as genome browsing functionality. All RNAcentral data is provided for free and is available for browsing, bulk downloads, and programmatic access at http://rnacentral.org/.
AbstractList RNAcentral is a database of non-coding RNA (ncRNA) sequences that aggregates data from specialised ncRNA resources and provides a single entry point for accessing ncRNA sequences of all ncRNA types from all organisms. Since its launch in 2014, RNAcentral has integrated twelve new resources, taking the total number of collaborating database to 22, and began importing new types of data, such as modified nucleotides from MODOMICS and PDB. We created new species-specific identifiers that refer to unique RNA sequences within a context of single species. The website has been subject to continuous improvements focusing on text and sequence similarity searches as well as genome browsing functionality. All RNAcentral data is provided for free and is available for browsing, bulk downloads, and programmatic access at http://rnacentral.org/.
RNAcentral is a database of non-coding RNA (ncRNA) sequences that aggregates data from specialised ncRNA resources and provides a single entry point for accessing ncRNA sequences of all ncRNA types from all organisms. Since its launch in 2014, RNAcentral has integrated twelve new resources, taking the total number of collaborating database to 22, and began importing new types of data, such as modified nucleotides from MODOMICS and PDB. We created new species-specific identifiers that refer to unique RNA sequences within a context of single species. The website has been subject to continuous improvements focusing on text and sequence similarity searches as well as genome browsing functionality. All RNAcentral data is provided for free and is available for browsing, bulk downloads, and programmatic access at rnacentral.org/.
RNAcentral is a database of non-coding RNA (ncRNA) sequences that aggregates data from specialised ncRNA resources and provides a single entry point for accessing ncRNA sequences of all ncRNA types from all organisms. Since its launch in 2014, RNAcentral has integrated twelve new resources, taking the total number of collaborating database to 22, and began importing new types of data, such as modified nucleotides from MODOMICS and PDB. We created new species-specific identifiers that refer to unique RNA sequences within a context of single species. The website has been subject to continuous improvements focusing on text and sequence similarity searches as well as genome browsing functionality. All RNAcentral data is provided for free and is available for browsing, bulk downloads, and programmatic access at http://rnacentral.org/.
RNAcentral is a database of non-coding RNA (ncRNA) sequences that aggregates data from specialised ncRNA resources and provides a single entry point for accessing ncRNA sequences of all ncRNA types from all organisms. Since its launch in 2014, RNAcentral has integrated twelve new resources, taking the total number of collaborating database to 22, and began importing new types of data, such as modified nucleotides from MODOMICS and PDB. We created new species-specific identifiers that refer to unique RNA sequences within a context of single species. Furthermore, the website has been subject to continuous improvements focusing on text and sequence similarity searches as well as genome browsing functionality.
RNAcentral is a database of non-coding RNA (ncRNA) sequences that aggregates data from specialised ncRNA resources and provides a single entry point for accessing ncRNA sequences of all ncRNA types from all organisms. Since its launch in 2014, RNAcentral has integrated twelve new resources, taking the total number of collaborating database to 22, and began importing new types of data, such as modified nucleotides from MODOMICS and PDB. We created new species-specific identifiers that refer to unique RNA sequences within a context of single species. The website has been subject to continuous improvements focusing on text and sequence similarity searches as well as genome browsing functionality. All RNAcentral data is provided for free and is available for browsing, bulk downloads, and programmatic access at http://rnacentral.org/.RNAcentral is a database of non-coding RNA (ncRNA) sequences that aggregates data from specialised ncRNA resources and provides a single entry point for accessing ncRNA sequences of all ncRNA types from all organisms. Since its launch in 2014, RNAcentral has integrated twelve new resources, taking the total number of collaborating database to 22, and began importing new types of data, such as modified nucleotides from MODOMICS and PDB. We created new species-specific identifiers that refer to unique RNA sequences within a context of single species. The website has been subject to continuous improvements focusing on text and sequence similarity searches as well as genome browsing functionality. All RNAcentral data is provided for free and is available for browsing, bulk downloads, and programmatic access at http://rnacentral.org/.
Author Fey, Petra
Puetz, Joern
Kalvari, Ioanna
Cole, James R
Dinger, Marcel E
Zhang, Zhang
Frankish, Adam
Gutell, Robin
Bruford, Elspeth A
Lau, Britney Y
Stadler, Peter F
Chen, Runsheng
Kay, Simon J E
Engel, Stacia R
Hatzigeorgiou, Artemis G
Vlachos, Ioannis S
Cochrane, Guy
Wood, Valerie
Zhu, Weimin
Zwieb, Christian W
Bujnicki, Janusz M
Mestdagh, Pieter
Paraskevopoulou, Maria D
Quek, Xiu Cheng
Cherry, J Michael
Basu, Siddhartha
Karlowski, Wojciech M
Cannone, Jamie J
Finn, Robert D
Berardini, Tanya Z
Gray, Kristian A
Zhao, Yi
McDonald, Daniel
Howe, Kevin L
Lowe, Todd M
Ma, Lina
Chan, Patricia P
Kenmochi, Naoya
Kersey, Paul J
Petrov, Anton I
Griffiths-Jones, Sam
Machnicka, Magdalena A
Volders, Pieter-Jan
Chai, Benli
Szymanski, Maciej
Wower, Jacek
Bateman, Alex
Huala, Eva
Clark, Michael B
Yoshihama, Maki
Kozomara, Ana
Williams, Kelly P
AuthorAffiliation 14 Michigan State University, East Lansing, MI 48824-1325, USA
24 Bioinformatics Group, Department of Computer Science, and Interdisciplinary Center for Bioinformatics, University of Leipzig, D-04107 Leipzig, Germany
21 "Jacobs University Bremen and Max Planck Institute for Marine Microbiology"
26 dictyBase, Northwestern University, Chicago, IL, USA
2 Faculty of Biology, Medicine and Health, University of Manchester, Oxford Road, Manchester M13 9PT, UK
4 Department of Biomolecular Engineering, University of California Santa Cruz, CA 95064, USA
3 Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire, CB10 1HH, UK
19 Center for Computational Biology and Bioinformatics, The University of Texas at Austin, Austin, TX 78712, USA
6 Department of Animal Sciences, Auburn University, Auburn, AL 36849, USA
18 Cambridge Systems Biology Centre & Department of Biochemistry, University of Cambridge, Sanger Building, 80 Tennis Court Road, Cambridge CB2 1GA, UK
5 Department of Bi
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– name: 25 Department of Pediatrics, University of California San Diego, La Jolla, CA, USA
– name: 2 Faculty of Biology, Medicine and Health, University of Manchester, Oxford Road, Manchester M13 9PT, UK
– name: 8 MRC Functional Genomics Unit, Department of Physiology, Anatomy, and Genetics, University of Oxford, Oxford OX1 3PT, UK
– name: 6 Department of Animal Sciences, Auburn University, Auburn, AL 36849, USA
– name: 3 Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire, CB10 1HH, UK
– name: 17 DIANA-Lab, Department of Electrical & Computer Engineering, University of Thessaly, 382 21 Volos, Greece Hellenic Pasteur Institute, 127 Vasilissis Sofias Avenue, 11521 Athens, Greece
– name: 7 Sandia National Laboratories, Livermore, CA 94551, USA
– name: 13 Data Science, National Center for Protein Science, Beijing, China
– name: 18 Cambridge Systems Biology Centre & Department of Biochemistry, University of Cambridge, Sanger Building, 80 Tennis Court Road, Cambridge CB2 1GA, UK
– name: 5 Department of Biochemistry, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, USA
– name: 15 Institute of Molecular Biology and Biotechnology, Faculty of Biology, Adam Mickiewicz University, Umultowska 89, 61-614 Poznan, Poland Department of Computational Biology, Adam Mickiewicz University in Poznan, Poland
– name: 22 BIG Data Center and CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China
– name: 24 Bioinformatics Group, Department of Computer Science, and Interdisciplinary Center for Bioinformatics, University of Leipzig, D-04107 Leipzig, Germany
– name: 10 Laboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology, Trojdena 4, 02-109 Warsaw, Poland
– name: 26 dictyBase, Northwestern University, Chicago, IL, USA
– name: 27 Center for Medical Genetics, Ghent University and Cancer Research Institute Ghent, Ghent University, Ghent, Belgium
– name: 9 Garvan Institute of Medical Research, Sydney, New South Wales 2010, Australia
– name: 20 The Arabidopsis Information Resource and Phoenix Bioinformatics, 643 Bair Island Rd. Suite 403, Redwood City, CA 94063, USA
– name: 11 Frontier Science Research Center, University of Miyazaki, Japan
– name: 4 Department of Biomolecular Engineering, University of California Santa Cruz, CA 95064, USA
– name: 12 Institute of Computing Technology, Chinese Academy of Sciences, Beijing 100190, China Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China
– name: 19 Center for Computational Biology and Bioinformatics, The University of Texas at Austin, Austin, TX 78712, USA
– name: 14 Michigan State University, East Lansing, MI 48824-1325, USA
– name: 21 "Jacobs University Bremen and Max Planck Institute for Marine Microbiology"
– name: 23 University of Strasbourg, 15 rue R. Descartes, 67084 Strasbourg, France
– name: 1 1European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
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– sequence: 2
  givenname: Simon J E
  surname: Kay
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– sequence: 3
  givenname: Ioanna
  surname: Kalvari
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  givenname: Robert D
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  givenname: Ana
  surname: Kozomara
  fullname: Kozomara, Ana
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  givenname: Sam
  surname: Griffiths-Jones
  fullname: Griffiths-Jones, Sam
  organization: Faculty of Biology, Medicine and Health, University of Manchester, Oxford Road, Manchester M13 9PT, UK
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  givenname: Adam
  surname: Frankish
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  organization: Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire, CB10 1HH, UK
– sequence: 14
  givenname: Christian W
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  organization: Frontier Science Research Center, University of Miyazaki, Japan
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  organization: Michigan State University, East Lansing, MI 48824-1325, USA
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– sequence: 29
  givenname: Valerie
  surname: Wood
  fullname: Wood, Valerie
  organization: Cambridge Systems Biology Centre & Department of Biochemistry, University of Cambridge, Sanger Building, 80 Tennis Court Road, Cambridge CB2 1GA, UK
– sequence: 30
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  surname: Huala
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  givenname: Tanya Z
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  organization: The Arabidopsis Information Resource and Phoenix Bioinformatics, 643 Bair Island Rd. Suite 403, Redwood City, CA 94063, USA
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  surname: Zhao
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  surname: Paraskevopoulou
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– sequence: 36
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  organization: DIANA-Lab, Department of Electrical & Computer Engineering, University of Thessaly, 382 21 Volos, Greece Hellenic Pasteur Institute, 127 Vasilissis Sofias Avenue, 11521 Athens, Greece
– sequence: 38
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  surname: Ma
  fullname: Ma, Lina
– sequence: 39
  givenname: Zhang
  surname: Zhang
  fullname: Zhang, Zhang
  organization: BIG Data Center and CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China
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  fullname: Puetz, Joern
  organization: University of Strasbourg, 15 rue R. Descartes, 67084 Strasbourg, France
– sequence: 41
  givenname: Peter F
  surname: Stadler
  fullname: Stadler, Peter F
  organization: Bioinformatics Group, Department of Computer Science, and Interdisciplinary Center for Bioinformatics, University of Leipzig, D-04107 Leipzig, Germany
– sequence: 42
  givenname: Daniel
  surname: McDonald
  fullname: McDonald, Daniel
  organization: Department of Pediatrics, University of California San Diego, La Jolla, CA, USA
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  fullname: Fey, Petra
  organization: dictyBase, Northwestern University, Chicago, IL, USA
– sequence: 45
  givenname: Stacia R
  surname: Engel
  fullname: Engel, Stacia R
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  organization: Department of Genetics, Stanford University, Stanford, CA 94305, USA
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  surname: Mestdagh
  fullname: Mestdagh, Pieter
  organization: Center for Medical Genetics, Ghent University and Cancer Research Institute Ghent, Ghent University, Ghent, Belgium
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  givenname: Jacek
  surname: Wower
  fullname: Wower, Jacek
  organization: Department of Animal Sciences, Auburn University, Auburn, AL 36849, USA
– sequence: 50
  givenname: Michael B
  surname: Clark
  fullname: Clark, Michael B
  organization: MRC Functional Genomics Unit, Department of Physiology, Anatomy, and Genetics, University of Oxford, Oxford OX1 3PT, UK
– sequence: 51
  givenname: Xiu Cheng
  surname: Quek
  fullname: Quek, Xiu Cheng
  organization: Garvan Institute of Medical Research, Sydney, New South Wales 2010, Australia
– sequence: 52
  givenname: Marcel E
  surname: Dinger
  fullname: Dinger, Marcel E
  organization: Garvan Institute of Medical Research, Sydney, New South Wales 2010, Australia
BackLink https://www.ncbi.nlm.nih.gov/pubmed/27794554$$D View this record in MEDLINE/PubMed
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Snippet RNAcentral is a database of non-coding RNA (ncRNA) sequences that aggregates data from specialised ncRNA resources and provides a single entry point for...
RNAcentral is a database of non-coding RNA (ncRNA) sequences that aggregates data from specialised ncRNA resources and provides a single entry point for...
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StartPage D128
SubjectTerms Animals
Database Issue
Databases, Nucleic Acid
genome
Genomics
Humans
nucleotides
Nucleotides - chemistry
rna
RNA, Untranslated - chemistry
Sequence Analysis, RNA
Species Specificity
Title RNAcentral: a comprehensive database of non-coding RNA sequences
URI https://www.ncbi.nlm.nih.gov/pubmed/27794554
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https://pubmed.ncbi.nlm.nih.gov/PMC5210518
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