Evaluation of the immunomodulatory effects of interleukin-10 on peripheral blood immune cells of COVID-19 patients: Implication for COVID-19 therapy

Several therapies with immune-modulatory functions have been proposed to reduce the overwhelmed inflammation associated with COVID-19. Here we investigated the impact of IL-10 in COVID-19, through the ex-vivo assessment of the effects of exogenous IL-10 on SARS-CoV-2-specific-response using a whole-...

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Bibliographic Details

Published in:	Frontiers in immunology Vol. 13; p. 984098
Main Authors:	Najafi-Fard, Saeid, Petruccioli, Elisa, Farroni, Chiara, Petrone, Linda, Vanini, Valentina, Cuzzi, Gilda, Salmi, Andrea, Altera, Anna Maria Gerarda, Navarra, Assunta, Alonzi, Tonino, Nicastri, Emanuele, Palmieri, Fabrizio, Gualano, Gina, Carlini, Valentina, Noonan, Douglas McClain, Albini, Adriana, Goletti, Delia
Format:	Journal Article
Language:	English
Published:	Frontiers Media S.A 06.09.2022
Subjects:	COVID-19 IL-10 Immunology Natutal Killer Cells SARS-CoV-2 spike whole-blood
ISSN:	1664-3224, 1664-3224
Online Access:	Get full text
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