A Novel Fragmentation Sensitivity Index Determines the Susceptibility of Red Blood Cells to Mechanical Trauma

Supraphysiological shear stresses (SSs) induce irreversible impairments of red blood cell (RBC) deformability, overstretching of RBC membrane, or fragmentation of RBCs that causes free hemoglobin to be released into plasma, which may lead to anemia. The magnitude and exposure tisme of the SSs are tw...

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Vydané v:	Frontiers in physiology Ročník 12; s. 714157
Hlavní autori:	Ugurel, Elif, Goksel, Evrim, Goktas, Polat, Cilek, Neslihan, Atar, Dila, Yalcin, Ozlem
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Frontiers Media S.A 25.08.2021
Predmet:	fragmentaton sensitivity index mechanical risk sensitivity metabolic depletion oxidative stress Physiology red blood cell fragmentation supra-physiological shear stress
ISSN:	1664-042X, 1664-042X
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