Galectin-3 expressed on different lung compartments promotes organ specific metastasis by facilitating arrest, extravasation and organ colonization via high affinity ligands on melanoma cells

Interactions between molecules on the surface of tumor cells and those on the target organ endothelium play an important role in their arrest in an organ. Galectin-3 on the lung endothelium and high affinity ligands poly- N -acetyllactosamine (polyLacNAc) on N-oligosaccharides on melanoma cells faci...

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Vydáno v:	Clinical & experimental metastasis Ročník 31; číslo 6; s. 661 - 673
Hlavní autoři:	Dange, Manohar C., Srinivasan, Nithya, More, Shyam K., Bane, Sanjay M., Upadhya, Archana, Ingle, Arvind D., Gude, Rajiv P., Mukhopadhyaya, Rabindranath, Kalraiya, Rajiv D.
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Dordrecht Springer Netherlands 01.08.2014 Springer Nature B.V
Témata:	Animals Base Sequence Biomedical and Life Sciences Biomedicine Blotting, Western Cancer Research Cell Adhesion Cell Line, Tumor DNA Primers Flow Cytometry Galectin 3 - metabolism Hematology Ligands Lung - metabolism Lung - pathology Melanoma, Experimental - pathology Mice Oncology Real-Time Polymerase Chain Reaction Research Paper Surgical Oncology Organ specific metastasis Lungs Extravasation β1,6 branched N-oligosaccharides acetyllactosamine Poly Galectin-3
ISSN:	0262-0898, 1573-7276, 1573-7276
On-line přístup:	Získat plný text
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