Randomized controlled trial of atorvastatin in mild to moderate Alzheimer disease: LEADe

There is some evidence that statins may have a protective and symptomatic benefit in Alzheimer disease (AD). The LEADe study is a randomized controlled trial (RCT) evaluating the efficacy and safety of atorvastatin in patients with mild to moderate AD. This was an international, multicenter, double-...

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Vydané v:	Neurology Ročník 74; číslo 12; s. 956
Hlavní autori:	Feldman, H H, Doody, R S, Kivipelto, M, Sparks, D L, Waters, D D, Jones, R W, Schwam, E, Schindler, R, Hey-Hadavi, J, DeMicco, D A, Breazna, A
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 23.03.2010
Predmet:	Aged Aged, 80 and over Alzheimer Disease - drug therapy Alzheimer Disease - metabolism Atorvastatin Calcium Cholesterol, LDL - metabolism Cholinergic Antagonists - therapeutic use Double-Blind Method Female Heptanoic Acids - therapeutic use Hippocampus - pathology Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use Magnetic Resonance Imaging Male Middle Aged Organ Size - drug effects Pyrroles - therapeutic use
ISSN:	1526-632X, 1526-632X
On-line prístup:	Zistit podrobnosti o prístupe
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