Glioma-Targeted Therapeutics: Computer-Aided Drug Design Prospective
Amongst the several types of brain cancers known to humankind, glioma is one of the most severe and life-threatening types of cancer, comprising 40% of all primary brain tumors. Recent reports have shown the incident rate of gliomas to be 6 per 100,000 individuals per year globally. Despite the vari...
Uloženo v:
| Vydáno v: | The Protein Journal Ročník 40; číslo 5; s. 601 - 655 |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Journal Article |
| Jazyk: | angličtina |
| Vydáno: |
New York
Springer US
01.10.2021
Springer Springer Nature B.V |
| Témata: | |
| ISSN: | 1572-3887, 1875-8355, 1573-4943, 1875-8355 |
| On-line přístup: | Získat plný text |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
|
| Abstract | Amongst the several types of brain cancers known to humankind, glioma is one of the most severe and life-threatening types of cancer, comprising 40% of all primary brain tumors. Recent reports have shown the incident rate of gliomas to be 6 per 100,000 individuals per year globally. Despite the various therapeutics used in the treatment of glioma, patient survival rate remains at a median of 15 months after undergoing first-line treatment including surgery, radiation, and chemotherapy with Temozolomide. As such, the discovery of newer and more effective therapeutic agents is imperative for patient survival rate. The advent of computer-aided drug design in the development of drug discovery has emerged as a powerful means to ascertain potential hit compounds with distinctively high therapeutic effectiveness against glioma. This review encompasses the recent advances of bio-computational in-silico modeling that have elicited the discovery of small molecule inhibitors and/or drugs against various therapeutic targets in glioma. The relevant information provided in this report will assist researchers, especially in the drug design domains, to develop more effective therapeutics against this global disease. |
|---|---|
| AbstractList | Amongst the several types of brain cancers known to humankind, glioma is one of the most severe and life-threatening types of cancer, comprising 40% of all primary brain tumors. Recent reports have shown the incident rate of gliomas to be 6 per 100,000 individuals per year globally. Despite the various therapeutics used in the treatment of glioma, patient survival rate remains at a median of 15 months after undergoing first-line treatment including surgery, radiation, and chemotherapy with Temozolomide. As such, the discovery of newer and more effective therapeutic agents is imperative for patient survival rate. The advent of computer-aided drug design in the development of drug discovery has emerged as a powerful means to ascertain potential hit compounds with distinctively high therapeutic effectiveness against glioma. This review encompasses the recent advances of bio-computational in-silico modeling that have elicited the discovery of small molecule inhibitors and/or drugs against various therapeutic targets in glioma. The relevant information provided in this report will assist researchers, especially in the drug design domains, to develop more effective therapeutics against this global disease. Amongst the several types of brain cancers known to humankind, glioma is one of the most severe and life-threatening types of cancer, comprising 40% of all primary brain tumors. Recent reports have shown the incident rate of gliomas to be 6 per 100,000 individuals per year globally. Despite the various therapeutics used in the treatment of glioma, patient survival rate remains at a median of 15 months after undergoing first-line treatment including surgery, radiation, and chemotherapy with Temozolomide. As such, the discovery of newer and more effective therapeutic agents is imperative for patient survival rate. The advent of computer-aided drug design in the development of drug discovery has emerged as a powerful means to ascertain potential hit compounds with distinctively high therapeutic effectiveness against glioma. This review encompasses the recent advances of bio-computational in-silico modeling that have elicited the discovery of small molecule inhibitors and/or drugs against various therapeutic targets in glioma. The relevant information provided in this report will assist researchers, especially in the drug design domains, to develop more effective therapeutics against this global disease.Amongst the several types of brain cancers known to humankind, glioma is one of the most severe and life-threatening types of cancer, comprising 40% of all primary brain tumors. Recent reports have shown the incident rate of gliomas to be 6 per 100,000 individuals per year globally. Despite the various therapeutics used in the treatment of glioma, patient survival rate remains at a median of 15 months after undergoing first-line treatment including surgery, radiation, and chemotherapy with Temozolomide. As such, the discovery of newer and more effective therapeutic agents is imperative for patient survival rate. The advent of computer-aided drug design in the development of drug discovery has emerged as a powerful means to ascertain potential hit compounds with distinctively high therapeutic effectiveness against glioma. This review encompasses the recent advances of bio-computational in-silico modeling that have elicited the discovery of small molecule inhibitors and/or drugs against various therapeutic targets in glioma. The relevant information provided in this report will assist researchers, especially in the drug design domains, to develop more effective therapeutics against this global disease. Amongst the several types of brain cancers known to humankind, glioma is one of the most severe and life-threatening types of cancer, comprising 40% of all primary brain tumors. Recent reports have shown the incident rate of gliomas to be 6 per 100,000 individuals per year globally. Despite the various therapeutics used in the treatment of glioma, patient survival rate remains at a median of 15 months after undergoing first-line treatment including surgery, radiation, and chemotherapy with Temozolomide. As such, the discovery of newer and more effective therapeutic agents is imperative for patient survival rate. The advent of computer-aided drug design in the development of drug discovery has emerged as a powerful means to ascertain potential hit compounds with distinctively high therapeutic effectiveness against glioma. This review encompasses the recent advances of bio-computational in-silico modeling that have elicited the discovery of small molecule inhibitors and/or drugs against various therapeutic targets in glioma. The relevant information provided in this report will assist researchers, especially in the drug design domains, to develop more effective therapeutics against this global disease. |
| Audience | Academic |
| Author | Agoni, Clement Poonan, Preantha Ibrahim, Mahmoud A. A. Soliman, Mahmoud E. S. |
| Author_xml | – sequence: 1 givenname: Preantha surname: Poonan fullname: Poonan, Preantha organization: Molecular Bio-Computation and Drug Design Laboratory, School of Health Sciences, University of KwaZulu-Natal, Westville Campus – sequence: 2 givenname: Clement surname: Agoni fullname: Agoni, Clement organization: Molecular Bio-Computation and Drug Design Laboratory, School of Health Sciences, University of KwaZulu-Natal, Westville Campus – sequence: 3 givenname: Mahmoud A. A. surname: Ibrahim fullname: Ibrahim, Mahmoud A. A. organization: Computational Chemistry Laboratory, Chemistry Department, Faculty of Science, Minia University – sequence: 4 givenname: Mahmoud E. S. orcidid: 0000-0002-0619-2109 surname: Soliman fullname: Soliman, Mahmoud E. S. email: soliman@ukzn.ac.za organization: Molecular Bio-Computation and Drug Design Laboratory, School of Health Sciences, University of KwaZulu-Natal, Westville Campus |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/34590194$$D View this record in MEDLINE/PubMed |
| BookMark | eNp9kUtv1DAUhS1URB_wB1igkdiwcfEjD5vdaIa2SJVgMawtx7kJrpI42E4r_j13Oq0qKlRZfn_n2LrnlBxNYQJC3nN2zhmrPyfOtGSUCU5xj-PdK3LCy1rSQhfy6H4tqFSqPianKd0go3Qt3pBjWZSacV2ckO3l4MNo6c7GHjK0q90viHaGJXuXvqw2YZyXDJGufYuX27j0qy0k30-rHzGkGVz2t_CWvO7skODdw3xGfl583W2u6PX3y2-b9TV1RSEy5V3BNZMOe9OArFpV8Ebw1moHouROyqJrG9UBq3QnlOVc1BXYClBX86qRZ-TTwXeO4fcCKZvRJwfDYCcISzKirBUvOVcC0Y_P0JuwxAl_t6e0qiqt5BPV2wGMn7qQo3V7U7PGF0tRl3pPnf-HwtbC6B1m0nk8_0fw4eHxpRmhNXP0o41_zGPZEVAHwGERU4TOOJ9t9mFCZz8Yzsw-YXNI2GC25j5hc4dS8Uz66P6iSB5ECeGph_hUjRdUfwFzurU7 |
| CitedBy_id | crossref_primary_10_1007_s13258_022_01312_2 crossref_primary_10_1016_j_gene_2023_147489 crossref_primary_10_1111_cns_14715 crossref_primary_10_1007_s12094_023_03167_9 crossref_primary_10_2174_0109298673266672231121173432 crossref_primary_10_1002_advs_202412517 crossref_primary_10_1016_j_ejmech_2024_117171 crossref_primary_10_1002_glia_24630 crossref_primary_10_1093_neuonc_noad159 crossref_primary_10_3389_fonc_2022_993316 crossref_primary_10_1093_neuonc_noad102 crossref_primary_10_1155_2023_1680634 crossref_primary_10_2174_0929867329666220919114919 crossref_primary_10_3389_fphar_2024_1485919 |
| Cites_doi | 10.2174/138920010791514306 10.1111/cbdd.12977 10.22034/APJCP.2017.18.1.3 10.1016/B978-0-12-809633-8.20197-0 10.3389/fimmu.2020.603911 10.1007/s00401-007-0243-4 10.1111/bpa.12837 10.1371/journal.pone.0229534 10.3389/fonc.2018.00464 10.1007/s12035-017-0599-y 10.1039/C8RA08427K 10.1007/s13277-014-2986-6 10.1016/j.semcancer.2019.09.023 10.1093/neuonc/nov127 10.18632/oncotarget.17054 10.3389/fonc.2013.00284 10.1155/2012/541431 10.3389/fonc.2019.01547 10.1517/14728220902942348 10.1016/j.sciaf.2020.e00570 10.1111/j.1747-0285.2010.00986.x 10.3171/jns.2001.94.3.0445 10.1177/153303461000900405 10.1038/nsmb1105 10.1155/2016/9734512 10.3171/2014.10.JNS141520 10.2174/187152009788680019 10.3322/caac.21660 10.1097/00019052-200112000-00002 10.1593/neo.10688 10.1007/s00109-004-0565-9 10.3389/fphar.2018.00879 10.1186/s13046-019-1235-7 10.2147/DDDT.S168130 10.18103/mra.v8i2.2034 10.1080/13543784.2018.1528225 10.1016/S1056-8719(00)00107-6 10.3390/cancers5031103 10.1021/acs.jmedchem.9b01423 10.1021/acschembio.5b00466 10.1093/neuonc/nov136 10.1016/j.canep.2019.07.001 10.3390/molecules25163633 10.1186/1741-7007-9-71 10.1007/s40487-016-0016-0 10.1038/sj.bjc.6603669 10.1002/tox.22581 10.1080/10428194.2019.1602260 10.1080/17460441.2020.1798926 10.1136/jnnp.20.1.22 10.1007/s11060-014-1612-1 10.1146/annurev.pathol.1.110304.100043 10.6004/jnccn.2011.0038 10.3389/fonc.2019.00506 10.2174/1874-470211205010102 10.1021/acsmedchemlett.9b00509 10.1039/c6ra21617j 10.18632/oncotarget.17464 10.1016/j.bmc.2019.05.040 10.3892/ol.2018.8873 10.1021/jm00368a016 10.3390/ijms150915994 10.1128/MCB.25.17.7734 10.1016/S0014-5793(00)02011-1 10.1128/mcb.25.17.7734-7742.2005 10.21776/ub.mnj.2019.005.02.9 10.1007/s11060-013-1354-5 10.1016/j.crad.2019.07.001 10.2217/cns-2019-0014 10.1200/JCO.19.03327 10.1016/j.trecan.2017.12.005 10.3892/ol.2017.6221 10.1016/b978-0-12-816125-8.00002-x 10.1016/j.esmoop.2021.100173 10.1155/2013/417413 10.1016/j.bcab.2019.101424 10.1155/2017/4649191 10.1093/neuonc/nou222 10.1093/neuonc/nou110 10.1093/neuonc/nov319 10.3389/fneur.2018.00033 10.4103/2152-7806.151348 10.1186/s13046-016-0362-7 10.1007/s00109-004-0564-x 10.31557/APJCP.2019.20.9.2681 10.17925/EE.2019.15.1.30 10.1093/bioinformatics/bti770 10.3390/cancers12123825 10.3390/molecules201219880 10.1007/s00330-004-2555-2 10.12688/f1000research.22440.1 10.1074/jbc.M207135200 10.3174/ajnr.A0750 10.1021/acs.jcim.0c01009 10.1080/10799893.2019.1690509 10.1016/j.cmet.2012.09.013 10.2174/157340607780059521 10.1186/2043-9113-1-5 10.1016/B978-0-323-47660-7.00006-9 10.1016/j.drup.2019.04.002 10.3390/ijms21061932 10.1080/10717544.2019.1616235 10.1007/s00586-018-5764-0 10.1007/s00401-016-1545-1 10.1124/jpet.112.197756 10.1080/14756366.2019.1673745 10.1016/j.bmc.2019.115217 10.1038/s41571-020-00447-z 10.1155/2013/285246 10.1038/nrdp.2015.17 10.2147/JRLCR.S46843 10.1073/pnas.1207759109 10.1007/s40487-019-00108-x 10.4172/2155-9872.1000356 10.1093/jnci/djq187 10.2147/ce.s172912 10.35118/apjmbb.2020.028.1.04 10.3390/molecules15064041 10.1021/acs.jcim.5b00733 10.1179/1743132814Y.0000000423 10.3238/arztebl.2018.0356 10.4155/fmc.10.241 10.1093/neuonc/noz126.072 10.3389/fneur.2017.00660 10.1186/s13046-018-0785-4 10.3390/cells8070715 10.1517/14728222.2012.711817 10.1073/pnas.1310894110 10.1016/j.ygeno.2019.05.024 10.1002/cnr2.1220 10.1186/s12885-015-1810-z 10.3389/fonc.2018.00419 10.1186/s12885-019-6511-6 10.1007/s11910-010-0109-3 10.1097/ppo.0000000000000326 10.1126/science.1254257 10.2174/1871520619666190405111526 10.3389/fonc.2019.00417 10.1007/s11060-017-2379-y 10.1016/j.bmcl.2017.12.030 10.2174/09298673113209990001 10.3389/fphar.2020.579768 10.1227/NEU.0000000000001365 10.4103/2152-7806.103029 10.1038/nsb0902-646 10.3389/fphar.2018.00923 10.1155/2016/1450843 10.1200/JCO.2009.26.3988 10.3892/ol.2020.11927 10.2176/nmc.ra.2018-0141 10.4103/ajns.ajns_39_15 10.1007/s13277-015-4242-0 10.1158/2159-8290.CD-16-1034 10.1586/erm.12.30 10.3390/molecules23040767 10.1016/j.matbio.2013.07.008 10.1002/cnr2.1226 10.3892/or.2019.7227 10.1016/j.ccr.2010.01.020 10.1016/j.jsb.2015.10.018 10.7150/jca.28231 10.1016/j.neo.2018.02.004 10.1016/B978-0-12-814421-3.00021-X 10.1093/neuonc/noy158 10.1200/JCO.2003.01.504 10.1182/blood-2011-11-390922 10.1007/s11064-016-1888-y 10.1101/gad.1596707 10.4103/jnrp.jnrp 10.3389/fonc.2017.00236 10.3174/ajnr.A2895 10.2174/1568026618666180101163651 10.1016/j.arabjc.2016.09.019 10.1016/S0305-7372(97)90019-0 10.3389/fonc.2017.00182 10.3389/fmolb.2020.562798 10.1007/s11060-010-0390-7 10.1186/s41016-019-0159-6 10.4103/sni.sni_490_16 10.1634/theoncologist.2009-0121 10.1212/CON.0000000000000536 10.2174/1570180815666180808094432 10.1093/jnen/62.12.1265 10.7314/APJCP.2014.15.7.3219 10.3390/ijms20061375 10.1186/s13046-019-1264-2 10.1038/nrm2039 10.1093/carcin/bgz134 10.18632/oncotarget.14109 10.1126/scitranslmed.3010611 10.3892/br.2018.1051 10.2217/cns.13.65 10.1038/s41598-017-05931-8 10.1093/neuonc/nos116 10.1016/B978-0-12-802997-8.00013-X 10.3978/j.issn.2305-5839.2015.03.57 10.1053/ctrv.1999.0145 10.1038/sj.onc.1206763 10.1006/bbrc.2000.2339 10.1016/j.cytogfr.2015.03.003 10.1007/s12017-013-8229-y 10.1142/9789813235533_0031 10.1021/acsomega.0c01323 10.1016/j.bmcl.2016.04.039 10.1007/s00401-009-0614-0 10.1109/SCEECS.2014.6804439 10.2174/1568009616666161227091522 |
| ContentType | Journal Article |
| Copyright | The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2021 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature. COPYRIGHT 2021 Springer The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2021. |
| Copyright_xml | – notice: The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2021 – notice: 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature. – notice: COPYRIGHT 2021 Springer – notice: The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2021. |
| DBID | AAYXX CITATION CGR CUY CVF ECM EIF NPM 3V. 7QL 7TK 7TM 7U7 7X7 7XB 88A 88E 88I 8AO 8FD 8FE 8FG 8FH 8FI 8FJ 8FK ABJCF ABUWG AEUYN AFKRA AZQEC BBNVY BENPR BGLVJ BHPHI C1K CCPQU D1I DWQXO FR3 FYUFA GHDGH GNUQQ HCIFZ K9. KB. LK8 M0S M1P M2P M7N M7P P64 PDBOC PHGZM PHGZT PJZUB PKEHL PPXIY PQEST PQGLB PQQKQ PQUKI Q9U RC3 7X8 |
| DOI | 10.1007/s10930-021-10021-w |
| DatabaseName | CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed ProQuest Central (Corporate) Bacteriology Abstracts (Microbiology B) Neurosciences Abstracts Nucleic Acids Abstracts Toxicology Abstracts Health & Medical Collection ProQuest Central (purchase pre-March 2016) Biology Database (Alumni Edition) Medical Database (Alumni Edition) Science Database (Alumni Edition) ProQuest Pharma Collection Technology Research Database ProQuest SciTech Collection ProQuest Technology Collection ProQuest Natural Science Journals Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) Materials Science & Engineering Collection ProQuest Central (Alumni) ProQuest One Sustainability ProQuest Central UK/Ireland ProQuest Central Essentials Biological Science Collection ProQuest Central Technology Collection Natural Science Collection Environmental Sciences and Pollution Management ProQuest One Community College ProQuest Materials Science Collection ProQuest Central Engineering Research Database Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Central Student SciTech Premium Collection ProQuest Health & Medical Complete (Alumni) Materials Science Database Biological Sciences ProQuest Health & Medical Collection Medical Database Science Database Algology Mycology and Protozoology Abstracts (Microbiology C) Biological Science Database Biotechnology and BioEngineering Abstracts Materials Science Collection ProQuest Central Premium ProQuest One Academic (New) ProQuest Health & Medical Research Collection ProQuest One Academic Middle East (New) ProQuest One Health & Nursing ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Applied & Life Sciences ProQuest One Academic (retired) ProQuest One Academic UKI Edition ProQuest Central Basic Genetics Abstracts MEDLINE - Academic |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) ProQuest Central Student ProQuest Central Essentials Nucleic Acids Abstracts SciTech Premium Collection Environmental Sciences and Pollution Management ProQuest One Applied & Life Sciences ProQuest One Sustainability Health Research Premium Collection Natural Science Collection Health & Medical Research Collection Biological Science Collection ProQuest Central (New) ProQuest Medical Library (Alumni) ProQuest Science Journals (Alumni Edition) ProQuest Biological Science Collection ProQuest One Academic Eastern Edition ProQuest Hospital Collection ProQuest Technology Collection Health Research Premium Collection (Alumni) Biological Science Database Neurosciences Abstracts ProQuest Hospital Collection (Alumni) Biotechnology and BioEngineering Abstracts ProQuest Health & Medical Complete ProQuest One Academic UKI Edition Engineering Research Database ProQuest One Academic ProQuest One Academic (New) Technology Collection Technology Research Database ProQuest One Academic Middle East (New) Materials Science Collection ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) ProQuest One Community College ProQuest One Health & Nursing ProQuest Natural Science Collection ProQuest Pharma Collection ProQuest Biology Journals (Alumni Edition) ProQuest Central ProQuest Health & Medical Research Collection Genetics Abstracts Health and Medicine Complete (Alumni Edition) ProQuest Central Korea Bacteriology Abstracts (Microbiology B) Algology Mycology and Protozoology Abstracts (Microbiology C) Materials Science Database ProQuest Materials Science Collection ProQuest Central Basic Toxicology Abstracts ProQuest Science Journals ProQuest SciTech Collection ProQuest Medical Library Materials Science & Engineering Collection ProQuest Central (Alumni) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE MEDLINE - Academic ProQuest Central Student |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: BENPR name: ProQuest Central url: https://www.proquest.com/central sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Anatomy & Physiology Chemistry |
| EISSN | 1573-4943 1875-8355 |
| EndPage | 655 |
| ExternalDocumentID | A716527593 34590194 10_1007_s10930_021_10021_w |
| Genre | Research Support, Non-U.S. Gov't Journal Article Review |
| GroupedDBID | --- -58 -5G -BR -EM -Y2 -~C .86 .GJ .VR 06D 0R~ 0VY 123 1N0 203 29P 2J2 2JN 2JY 2KG 2KM 2LR 2P1 30V 3V. 4.4 406 408 409 40D 40E 53G 5VS 67Z 6NX 78A 88A 8UJ 95- 95. 95~ 96X AAAVM AABHQ AACDK AAHNG AAIAL AAIKT AAJBT AAJKR AANZL AARHV AARTL AASML AATNV AAYIU AAYQN AAYZH ABAKF ABDZT ABECU ABFTV ABHLI ABJCF ABJOX ABKCH ABKTR ABMNI ABMQK ABNWP ABQBU ABQSL ABSXP ABTEG ABTHY ABTKH ABTMW ABULA ABXPI ACAOD ACGFO ACGFS ACGOD ACHSB ACHXU ACIWK ACKNC ACMDZ ACMLO ACOKC ACPIV ACPRK ACZOJ ADBBV ADHIR ADKPE ADPHR ADRFC ADTPH ADURQ ADYFF ADYOE ADZKW AEBTG AEFQL AEGNC AEJHL AEJRE AEKMD AEMSY AENEX AEOHA AEPYU AESKC AETLH AEUYN AEVLU AEXYK AFBBN AFEXP AFKRA AFLOW AFRAH AFWTZ AFYQB AFZKB AGDGC AGGDS AGJBK AGMZJ AGQEE AGQMX AGWIL AGWZB AGYKE AHAVH AHMBA AHSBF AHYZX AIAKS AIGIU AIIXL AILAN AITGF AJBLW AJRNO AJZVZ ALIPV ALMA_UNASSIGNED_HOLDINGS ALWAN AMKLP AMTXH AMXSW AOCGG ARMRJ AXYYD AYJHY AZFZN AZQEC B-. BA0 BDATZ BENPR BGLVJ BGNMA BPHCQ BSONS CAG CCPQU COF CS3 CSCUP DDRTE DL5 DNIVK DPUIP DU5 EBD EBLON EBS EIOEI EJD EMOBN EPAXT ESBYG F5P FEDTE FERAY FFXSO FIGPU FINBP FNLPD FRRFC FSGXE FWDCC G-Y G-Z GGCAI GGRSB GJIRD GNWQR GQ6 GQ7 GQ8 GXS HCIFZ HF~ HG5 HG6 HMCUK HMJXF HQYDN HRMNR HVGLF HZ~ I09 I5X IAO IHE IHR IKXTQ ITC ITM IWAJR IXC IZIGR IZQ I~X I~Z J-C J0Z JBSCW JCJTX JZLTJ KB. KDC KOV LAK LLZTM M0L M2P M4Y M7P M7R MA- MVM N2Q NB0 NDZJH NPVJJ NQJWS NU0 O9- O93 O9G O9I O9J OVD P19 PDBOC PF0 PQQKQ PROAC PSQYO PT4 PT5 Q2X QOR QOS R89 R9I RIG RNI RNS ROL RPX RRX RSV RZC RZE RZK S16 S1Z S26 S27 S28 S3B SAP SCLPG SCM SDH SDM SHX SISQX SJYHP SNE SNPRN SNX SOHCF SOJ SPISZ SRMVM SSLCW STPWE SV3 SZN T13 T16 TEORI TSG TSK TSV TUC TUS U2A U9L UG4 UKHRP UOJIU UTJUX UZXMN VC2 VFIZW VXZ W23 W48 WJK WK8 YLTOR Z45 Z7U Z87 Z8O Z91 ZMTXR ~A9 AAPKM AAUYE AAYXX ABBRH ABDBE ABFSG ABRTQ ACSTC ADHKG AEZWR AFDZB AFFHD AFHIU AFOHR AGQPQ AHPBZ AHWEU AIXLP ATHPR AYFIA CITATION PHGZM PHGZT PJZUB PPXIY PQGLB CGR CUY CVF ECM EIF NPM 7QL 7TK 7TM 7U7 7X7 7XB 88E 88I 8AO 8FD 8FE 8FG 8FH 8FI 8FJ 8FK ABUWG BBNVY BHPHI C1K D1I DWQXO FR3 FYUFA GNUQQ K9. LK8 M1P M7N P64 PKEHL PQEST PQUKI Q9U RC3 7X8 PUEGO |
| ID | FETCH-LOGICAL-c442t-1f41903c903bbe36d841b21da9ce251c334fdb8fe069f28a11276ea6ef41716b3 |
| IEDL.DBID | M2P |
| ISICitedReferencesCount | 17 |
| ISICitedReferencesURI | http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000701350800001&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| ISSN | 1572-3887 1875-8355 |
| IngestDate | Wed Oct 01 14:25:21 EDT 2025 Wed Nov 05 04:05:04 EST 2025 Sat Nov 29 13:17:55 EST 2025 Sat Nov 29 09:48:27 EST 2025 Wed Feb 19 02:27:16 EST 2025 Sat Nov 29 02:24:09 EST 2025 Tue Nov 18 21:29:38 EST 2025 Fri Feb 21 02:47:11 EST 2025 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 5 |
| Keywords | Glioma treatment Computer-aided drug design Small molecule inhibitors Therapeutic targets |
| Language | English |
| License | 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c442t-1f41903c903bbe36d841b21da9ce251c334fdb8fe069f28a11276ea6ef41716b3 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 ObjectType-Review-3 content type line 23 |
| ORCID | 0000-0002-0619-2109 |
| PMID | 34590194 |
| PQID | 2579866983 |
| PQPubID | 54632 |
| PageCount | 55 |
| ParticipantIDs | proquest_miscellaneous_2578151182 proquest_journals_2579866983 gale_infotracmisc_A716527593 gale_infotracacademiconefile_A716527593 pubmed_primary_34590194 crossref_citationtrail_10_1007_s10930_021_10021_w crossref_primary_10_1007_s10930_021_10021_w springer_journals_10_1007_s10930_021_10021_w |
| PublicationCentury | 2000 |
| PublicationDate | 20211000 2021-10-00 20211001 |
| PublicationDateYYYYMMDD | 2021-10-01 |
| PublicationDate_xml | – month: 10 year: 2021 text: 20211000 |
| PublicationDecade | 2020 |
| PublicationPlace | New York |
| PublicationPlace_xml | – name: New York – name: Netherlands |
| PublicationTitle | The Protein Journal |
| PublicationTitleAbbrev | Protein J |
| PublicationTitleAlternate | Protein J |
| PublicationYear | 2021 |
| Publisher | Springer US Springer Springer Nature B.V |
| Publisher_xml | – name: Springer US – name: Springer – name: Springer Nature B.V |
| References | Holleczek, Zampella, Urbschat (CR22) 2019 Franceschi, Seidel, Sahm (CR28) 2021; 6 Liu, Wen, Gao (CR154) 2020; 35 Ulbricht, Brockmann, Aigner (CR175) 2003; 62 Batchelor, Duda, Di Tomaso (CR90) 2010; 28 Hanif, Muzaffar, Perveen (CR58) 2017; 18 CR162 Zhang, Xia, Liu (CR39) 2020; 7 Dawson, Berger, Lin (CR165) 2005; 25 Fang, Liu, Lu (CR205) 2019; 5 Lavecchia, Di Giovanni (CR108) 2013; 20 Jin, Xiao, Song (CR20) 2016; 41 Lu, Saha, Martuza (CR89) 2015; 121 Valdebenito, Medina (CR190) 2019; 2 Verma, Khan, Akhtar (CR134) 2019; 12 Huang, Yu, Tu (CR183) 2019; 9 Hervey-Jumper, Li, Lau (CR196) 2015; 123 Hospital, Goñi, Orozco, Gelpí (CR103) 2015; 8 Benjamin, Cozzo, Ji (CR76) 2013; 110 Fiorentini, Capelli, Saraceni (CR10) 2020; 8 Nguyen, Nguyen, Vock (CR207) 2013; 3 McTigue, Murray, Chen (CR127) 2012; 109 Ye, Guan, Xiong (CR185) 2018; 4 Nandakumar, Mansouri, Das (CR43) 2017; 7 Stevens, Hickman, Stone (CR59) 1984; 27 Feng, Yan, Zhao (CR93) 2016 Stamos, Sliwkowski, Eigenbrot (CR122) 2002; 277 Peter, Dhanjal, Malik, Ranganathan (CR114) 2019 Chang, Narayana (CR201) 2010; 9 Kut, Chaichana, Xi (CR198) 2015 Fakhran, Escott (CR26) 2008; 29 Yu, Zhang, Wei, Shao (CR38) 2020; 9 Müller, Kunkel, Lamszus (CR174) 2003; 22 Fujikawa, Sugawara, Tanaka (CR124) 2017; 7 Wang, Tang, Lai (CR145) 2020; 11 Alphandéry (CR206) 2018; 9 Kim, Umemura, Leung (CR68) 2018; 24 Yen, Travins, Wang (CR129) 2017; 7 Zheng, Sun, Gao (CR144) 2017; 8 Patel, Tirosh, Trombetta (CR176) 2014; 344 Golub, Iyengar, Dogra (CR95) 2019 Khan, Tao, Tong (CR128) 2006; 13 Mendelsohn, Baselga (CR80) 2003; 21 Krcek, Matschke, Theis (CR166) 2017; 7 Zhai, Beittenmiller, Wang (CR173) 1993; 53 Brozzo, Bjelić, Kisko (CR123) 2012; 119 Aflorei, Korbonits (CR24) 2014; 117 Aljoundi, Agoni, Fisaso, Soliman (CR100) 2019; 19 Kaserer, Beck, Akram (CR113) 2015; 20 Bagley, Connors, Aoun (CR29) 2020; 9 Zhu, Liu, Zhang (CR140) 2015; 36 Waitkus, Diplas, Yan (CR186) 2016; 18 (CR56) 2009; 6 Bakker, Jacobs, Pondaag (CR31) 2018; 27 Dar, Mir (CR105) 2017 Padiadpu, Mishra, Sharma (CR78) 2016; 56 Han, Kamdar (CR193) 2018 Weller, Wick, Aldape (CR9) 2015 Galkin, Jonas (CR94) 2019; 14 Aquilanti, Miller, Santagata (CR41) 2018; 20 Vigneswaran, Neill, Hadjipanayis (CR33) 2015; 3 Sepúlveda, Sánchez-Gómez, Vaz Salgado (CR84) 2018; 27 Reifenberger, Collins (CR18) 2004; 82 Chowdhary, Ene, Silbergeld (CR48) 2015; 6 Ma, Lin, Lin (CR92) 2018; 33 Pan, Liu, Chen (CR107) 2018; 23 Kanu, Mehta, Di (CR71) 2009; 13 Zong, Verhaak, Canolk (CR8) 2012; 12 Wang, Wang, Wang, Chen (CR63) 2019; 26 Nanegrungsunk, Onchan, Chattipakorn, Chattipakorn (CR51) 2015; 37 Franceschi, Cavallo, Lonardi (CR79) 2007; 96 Lassman, Sepúlveda-Sánchez, Cloughesy (CR91) 2019; 30 Barr (CR178) 2010; 2 Zou, Pusch, Eisel (CR147) 2016; 6 Belter, Barciszewski, Barciszewska (CR54) 2020; 15 Konteatis, Artin, Nicolay (CR77) 2020; 11 Duan, Liu, Niu (CR148) 2019; 27 Holland (CR6) 2001; 14 Louis, Perry, Reifenberger (CR35) 2016; 131 Goldbrunner, Ruge, Kocher (CR5) 2018 Dhermain, Barani (CR53) 2016; 134 Chen, Zhang, He (CR75) 2020; 20 Caravella, Lin, Diebold (CR149) 2020; 63 Chiang, Kovanlikaya, Choi (CR197) 2018; 9 Thorne, Zanca, Furnari (CR160) 2016; 18 CR210 Liu, Chen, Shi (CR82) 2019; 38 Bao, Zhou, Luo (CR88) 2014; 15 Zou, Pusch, Hua (CR146) 2018; 28 Chandra, Bhagavat, Sharma (CR151) 2011; 1 Durrant, McCammon (CR104) 2011; 9 Simpson (CR23) 1957; 20 Cervio, Villalonga, Mormandi (CR32) 2017 Shen, Zhang, Cheng (CR86) 2018; 37 Frey, Schilt, Strack (CR204) 2014; 16 Huang, Li, Li (CR69) 2021; 11 Prieto-Martínez, Medina-Franco (CR106) 2018; 21 Yadav, Khandelwal, Mudgal (CR136) 2019; 20 Agoni, Ramharack, Soliman (CR139) 2018; 8 Szymanski, Perry, Gage (CR203) 2001; 94 Panicker, Melge, Biswas (CR133) 2017; 90 Booth, Williams, Luis (CR189) 2020; 75 Tseng, Hsu, Chen, Tseng (CR65) 2017; 12 Xu, Wu, Zhu (CR168) 2013 Reitman, Yan (CR182) 2010; 102 Vengoji, Macha, Nimmakayala (CR85) 2019; 38 Khalid, Carone, Dumrongpisutikul (CR211) 2012; 33 Hung, Hong, Lee (CR46) 2000; 269 Navis, Van Den Eijnden, Schepens (CR74) 2010; 119 Arnold, Bordoli, Kopp, Schwede (CR117) 2006; 22 Newlands, Stevens, Wedge (CR57) 1997; 23 Liang, Schulder (CR200) 2012 Vollmann-Zwerenz, Leidgens, Feliciello (CR50) 2020; 21 Mellinghoff, Ellingson, Touat (CR96) 2020; 38 Coniglio, Segall (CR15) 2013; 32 Solca, Dahl, Zoephel (CR125) 2012; 343 Lee, Urman, Desai (CR181) 2019; 60 Zhao, Wang, Zheng (CR132) 2017 Roth, Weller (CR161) 2014; 16 Clark, Waszkowycz, Wong (CR188) 2016; 26 Hajalsiddig, Osman, Saeed (CR135) 2020; 5 Maddahi, Zareinia, Gan (CR195) 2016 Wen, Huse (CR37) 2017; 23 Makhlin, Salinas, Zhang (CR81) 2019; 8 Ludwig, Kornblum (CR42) 2017; 134 Gupta, Dwivedi (CR19) 2017; 8 Zhu, Du, Lu, Zhu (CR60) 2017; 8 Salmaso, Moro (CR102) 2018; 9 Boele, Klein, Reijneveld (CR3) 2014; 3 Yang, Yang, Pike, Marshall (CR131) 2010; 76 Reardon, Turner, Peters (CR167) 2011; 9 CR208 Gimeno, Ojeda-Montes, Tomás-Hernández (CR110) 2019; 20 Chae, Ranganath, Hammerman (CR169) 2017; 8 Li, Graeber (CR13) 2012; 14 Ya’u Ibrahim, Uzairu, Shallangwa, Abechi (CR121) 2020; 10 Varlamov, McCartney, Fleseriu (CR25) 2019; 15 Nieder, Petersen, Petersen, Thames (CR44) 2000; 26 Kar, Leszczynski (CR116) 2020; 15 Khedkar, Malde, Coutinho, Srivastava (CR112) 2007; 3 Patterson, Wongsurawat, Rodriguez (CR52) 2020; 8 Tonks (CR172) 2006; 7 Niu, Liang, Lu (CR192) 2020; 112 Walters, Wang (CR109) 2020; 60 Romani, Pistillo, Carosio (CR70) 2018; 8 Gallo, Nelson, Meyer, Donoghue (CR170) 2015; 26 Orr (CR27) 2020; 30 McNamara, Sahebjam, Mason (CR45) 2013; 5 Gerstner, Eichler, Plotkin (CR87) 2011; 103 Salama, Heier, Patel (CR202) 2018; 8 Liang, Lv, Lu (CR1) 2020; 20 Sung, Ferlay, Siegel (CR2) 2021; 71 Chandrasekaran, Abed, Al-Attraqchi (CR119) 2018 Saleem, Kulsoom Abdul, Küçükosmanoglu (CR156) 2019; 43 Jiapaer, Furuta, Tanaka (CR62) 2018; 58 Jain (CR66) 2018; 8 Tripathi, Imran (CR130) 2020; 28 Jimenez-Pascual, Siebzehnrubl (CR73) 2019; 8 Rathke-Hartlieb, Budde, Ewert (CR14) 2000; 481 Heery (CR30) 2016; 4 Silbey, American, July, Dobbin (CR164) 2016 Hartmann, Mueller, Von Deimling (CR21) 2004; 82 Zakrzewski, Jarzab, Pfeifer (CR209) 2015; 15 Xia, Ouyang, Li (CR177) 2019; 10 Weller, van den Bent, Preusser (CR4) 2021; 18 Zhang, Stevens, Bradshaw (CR55) 2012; 5 Yang, Pusch, Jennings (CR150) 2019; 16 Ozgencil, Eren, Ozkan (CR152) 2020; 28 Louis (CR16) 2006; 1 Zhu, Liu, Yang (CR34) 2014; 15 Guo, Han, Shi (CR187) 2019; 42 Vuong, Altibi, Duong (CR47) 2018; 55 Qian, Zhu (CR141) 2018; 12 Gilbert, Ruda, Soffietti (CR36) 2010; 10 Xu, Zong, Ma (CR159) 2017; 14 Pavlov, Meyronet, Meyer-Bisch (CR199) 2016; 79 Tareq Hassan Khan (CR118) 2010; 11 Loew, Schmidt, Unterberg, Halatsch (CR157) 2012; 9 Karplus, McCammon (CR101) 2002; 9 Ardizzone, Scuderi, Giuffrida (CR171) 2020; 12 Ward, Patel, Wise (CR40) 2010; 17 Usha, Shanmugarajan, Goyal (CR97) 2018; 17 Yang, Li, He, Zhu (CR142) 2018; 8 Furnari, Fenton, Bachoo (CR17) 2007; 21 Lutfiya, Priya, Manzoor, Hemalatha (CR137) 2019; 22 Tanuma, Katsuragi, Oyama (CR153) 2020; 25 Benjamin, Cravatt, Nomura (CR179) 2012; 16 Placone, Quiñones-Hinojosa, Searson (CR11) 2016; 37 Louis, Ohgaki, Wiestler (CR7) 2007; 114 Romero, Zanini, Ducati (CR212) 2012; 2012 Prieto-Martínez, López-López, Eurídice Juárez-Mercado, Medina-Franco (CR98) 2019 Wei, Gabrusiewicz, Heimberger (CR12) 2013 Valdebenito, D’Amico, Eugenin (CR194) 2019; 2 Wang, Tang, Liang (CR49) 2016; 35 Rathi, Kumar, Kini (CR138) 2019; 39 Huang (CR184) 2019; 40 Raisa, Marhaendraputro (CR64) 2019; 5 Wilms, Demaerel, Sunaert (CR213) 2005; 15 Yosaatmadja, Silva, Dickson (CR126) 2015; 192 Lipinski (CR120) 2000; 44 Wang, Yuan, Wu (CR115) 2017; 12 Endersby, Whitehouse, Hii (CR83) 2018; 20 Qing, Lee, De Raeymaeker (CR111) 2014; 7 Hatanpaa, Burma, Zhao, Habib (CR158) 2010; 12 Kalman, Szep, Garzuly, Post (CR155) 2013; 15 Cohen, Shen, Keegan, Pazdur (CR67) 2009; 14 Choowongkomon, Sawatdichaikul, Songtawee, Limtrakul (CR163) 2010; 15 Robles Irizarry, Hambardzumyan, Nakano (CR72) 2012; 16 Mottini, Napolitano, Li (CR99) 2021; 68 Macyszyn, Akbari, Pisapia (CR191) 2016; 18 Hottinger, Abdullah, Stupp (CR61) 2016 Zhu, Han, Ma, Yang (CR143) 2018; 16 Piano, Benjamin, Valente (CR180) 2015; 10 I Makhlin (10021_CR81) 2019; 8 AC Navis (10021_CR74) 2010; 119 M Tareq Hassan Khan (10021_CR118) 2010; 11 C Kut (10021_CR198) 2015 D Wang (10021_CR63) 2019; 26 M Yadav (10021_CR136) 2019; 20 G Verma (10021_CR134) 2019; 12 N Raisa (10021_CR64) 2019; 5 R Endersby (10021_CR83) 2018; 20 YU Zhu (10021_CR143) 2018; 16 S Lee (10021_CR181) 2019; 60 J Feng (10021_CR93) 2016 M Weller (10021_CR9) 2015 DA Reardon (10021_CR167) 2011; 9 WP Walters (10021_CR109) 2020; 60 DN Louis (10021_CR16) 2006; 1 P Zhang (10021_CR39) 2020; 7 E Alphandéry (10021_CR206) 2018; 9 YK Chae (10021_CR169) 2017; 8 J Padiadpu (10021_CR78) 2016; 56 S Müller (10021_CR174) 2003; 22 F Solca (10021_CR125) 2012; 343 X Liu (10021_CR82) 2019; 38 AP Patel (10021_CR176) 2014; 344 PS Ward (10021_CR40) 2010; 17 DI Benjamin (10021_CR76) 2013; 110 C Mottini (10021_CR99) 2021; 68 SC Peter (10021_CR114) 2019 CA Lipinski (10021_CR120) 2000; 44 MR Gilbert (10021_CR36) 2010; 10 E Franceschi (10021_CR28) 2021; 6 LH Gallo (10021_CR170) 2015; 26 J Durrant (10021_CR104) 2011; 9 R Goldbrunner (10021_CR5) 2018 L Yang (10021_CR150) 2019; 16 X Qing (10021_CR111) 2014; 7 Y Maddahi (10021_CR195) 2016 F Zou (10021_CR147) 2016; 6 J Liu (10021_CR154) 2020; 35 JM Sepúlveda (10021_CR84) 2018; 27 L Khalid (10021_CR211) 2012; 33 ZJ Reitman (10021_CR182) 2010; 102 Y Zhu (10021_CR34) 2014; 15 K Choowongkomon (10021_CR163) 2010; 15 A Fujikawa (10021_CR124) 2017; 7 Y Wang (10021_CR145) 2020; 11 A Cervio (10021_CR32) 2017 X Fang (10021_CR205) 2019; 5 J Huang (10021_CR183) 2019; 9 J Wei (10021_CR12) 2013 F Hanif (10021_CR58) 2017; 18 10021_CR162 Z Konteatis (10021_CR77) 2020; 11 JP Dawson (10021_CR165) 2005; 25 FR Romero (10021_CR212) 2012; 2012 DI Benjamin (10021_CR179) 2012; 16 MM Kim (10021_CR68) 2018; 24 V Salmaso (10021_CR102) 2018; 9 SA Khedkar (10021_CR112) 2007; 3 NK Tonks (10021_CR172) 2006; 7 H Saleem (10021_CR156) 2019; 43 F Ozgencil (10021_CR152) 2020; 28 DN Louis (10021_CR35) 2016; 131 S Kar (10021_CR116) 2020; 15 J Valdebenito (10021_CR190) 2019; 2 EC Holland (10021_CR6) 2001; 14 M Chowdhary (10021_CR48) 2015; 6 EV Varlamov (10021_CR25) 2019; 15 D Golub (10021_CR95) 2019 L Lu (10021_CR89) 2015; 121 TT Batchelor (10021_CR90) 2010; 28 B Niu (10021_CR192) 2020; 112 MG McNamara (10021_CR45) 2013; 5 TC Booth (10021_CR189) 2020; 75 A Gupta (10021_CR19) 2017; 8 M Galkin (10021_CR94) 2019; 14 B Chandrasekaran (10021_CR119) 2018 T Usha (10021_CR97) 2018; 17 ES Newlands (10021_CR57) 1997; 23 KK Jain (10021_CR66) 2018; 8 E Franceschi (10021_CR79) 2007; 96 K Arnold (10021_CR117) 2006; 22 SS Silbey (10021_CR164) 2016 Z Xia (10021_CR177) 2019; 10 CR Heery (10021_CR30) 2016; 4 SL Hervey-Jumper (10021_CR196) 2015; 123 R Krcek (10021_CR166) 2017; 7 J Liang (10021_CR1) 2020; 20 J Bao (10021_CR88) 2014; 15 Y Jin (10021_CR20) 2016; 41 A Hospital (10021_CR103) 2015; 8 FD Prieto-Martínez (10021_CR98) 2019 Z Ya’u Ibrahim (10021_CR121) 2020; 10 LE Huang (10021_CR184) 2019; 40 GC Chiang (10021_CR197) 2018; 9 TTH Hajalsiddig (10021_CR135) 2020; 5 D Nanegrungsunk (10021_CR51) 2015; 37 World C (10021_CR56) 2009; 6 B Huang (10021_CR69) 2021; 11 IK Mellinghoff (10021_CR96) 2020; 38 D Tripathi (10021_CR130) 2020; 28 YS Ma (10021_CR92) 2018; 33 T Kaserer (10021_CR113) 2015; 20 L Macyszyn (10021_CR191) 2016; 18 Q Guo (10021_CR187) 2019; 42 K Yen (10021_CR129) 2017; 7 D Liang (10021_CR200) 2012 P Roth (10021_CR161) 2014; 16 B Kalman (10021_CR155) 2013; 15 S Valdebenito (10021_CR194) 2019; 2 P Nandakumar (10021_CR43) 2017; 7 CA Bagley (10021_CR29) 2020; 9 J Shen (10021_CR86) 2018; 37 Z Duan (10021_CR148) 2019; 27 V Piano (10021_CR180) 2015; 10 F Zou (10021_CR146) 2018; 28 HG Vuong (10021_CR47) 2018; 55 M Zhao (10021_CR132) 2017 MD Szymanski (10021_CR203) 2001; 94 D Frey (10021_CR204) 2014; 16 AL Placone (10021_CR11) 2016; 37 HY Wang (10021_CR49) 2016; 35 SJ Coniglio (10021_CR15) 2013; 32 R Vengoji (10021_CR85) 2019; 38 L Robles Irizarry (10021_CR72) 2012; 16 A Gimeno (10021_CR110) 2019; 20 L Qian (10021_CR141) 2018; 12 D Ye (10021_CR185) 2018; 4 MH Cohen (10021_CR67) 2009; 14 M Karplus (10021_CR101) 2002; 9 JA Caravella (10021_CR149) 2020; 63 A Lavecchia (10021_CR108) 2013; 20 E Rathi (10021_CR138) 2019; 39 Y-L Pan (10021_CR107) 2018; 23 W Li (10021_CR13) 2012; 14 D Simpson (10021_CR23) 1957; 20 S Loew (10021_CR157) 2012; 9 W Yu (10021_CR38) 2020; 9 F Prieto-Martínez (10021_CR106) 2018; 21 AH Thorne (10021_CR160) 2016; 18 MS Waitkus (10021_CR186) 2016; 18 A Ardizzone (10021_CR171) 2020; 12 M Weller (10021_CR4) 2021; 18 DN Louis (10021_CR7) 2007; 114 FB Furnari (10021_CR17) 2007; 21 SI Tanuma (10021_CR153) 2020; 25 J Patterson (10021_CR52) 2020; 8 MFG Stevens (10021_CR59) 1984; 27 K Ludwig (10021_CR42) 2017; 134 A Vollmann-Zwerenz (10021_CR50) 2020; 21 AS Lutfiya (10021_CR137) 2019; 22 H Sung (10021_CR2) 2021; 71 M Romani (10021_CR70) 2018; 8 C Agoni (10021_CR139) 2018; 8 B Yang (10021_CR142) 2018; 8 J Chang (10021_CR201) 2010; 9 ER Gerstner (10021_CR87) 2011; 103 S Fakhran (10021_CR26) 2008; 29 PS Panicker (10021_CR133) 2017; 90 YF Zhai (10021_CR173) 1993; 53 AM Dar (10021_CR105) 2017 A Fiorentini (10021_CR10) 2020; 8 Y Zhu (10021_CR140) 2015; 36 M McTigue (10021_CR127) 2012; 109 GR Salama (10021_CR202) 2018; 8 10021_CR208 S Rathke-Hartlieb (10021_CR14) 2000; 481 FW Boele (10021_CR3) 2014; 3 L Chen (10021_CR75) 2020; 20 J Mendelsohn (10021_CR80) 2003; 21 K Vigneswaran (10021_CR33) 2015; 3 BA Orr (10021_CR27) 2020; 30 SH Bakker (10021_CR31) 2018; 27 E Aquilanti (10021_CR41) 2018; 20 KJ Hatanpaa (10021_CR158) 2010; 12 PY Wen (10021_CR37) 2017; 23 N Chandra (10021_CR151) 2011; 1 J Stamos (10021_CR122) 2002; 277 A Jimenez-Pascual (10021_CR73) 2019; 8 G Wilms (10021_CR213) 2005; 15 C Nieder (10021_CR44) 2000; 26 Y Yosaatmadja (10021_CR126) 2015; 192 10021_CR210 V Pavlov (10021_CR199) 2016; 79 W-L Tseng (10021_CR65) 2017; 12 S Jiapaer (10021_CR62) 2018; 58 M Zheng (10021_CR144) 2017; 8 A Barr (10021_CR178) 2010; 2 AF Hottinger (10021_CR61) 2016 G Reifenberger (10021_CR18) 2004; 82 T Wang (10021_CR115) 2017; 12 C Hartmann (10021_CR21) 2004; 82 K Zakrzewski (10021_CR209) 2015; 15 J Zhang (10021_CR55) 2012; 5 U Ulbricht (10021_CR175) 2003; 62 B Holleczek (10021_CR22) 2019 AK Aljoundi (10021_CR100) 2019; 19 KS Hung (10021_CR46) 2000; 269 OO Kanu (10021_CR71) 2009; 13 DE Clark (10021_CR188) 2016; 26 NP Nguyen (10021_CR207) 2013; 3 ED Aflorei (10021_CR24) 2014; 117 JA Khan (10021_CR128) 2006; 13 L Han (10021_CR193) 2018 RYC Yang (10021_CR131) 2010; 76 H Zong (10021_CR8) 2012; 12 P Zhu (10021_CR60) 2017; 8 F Dhermain (10021_CR53) 2016; 134 A Belter (10021_CR54) 2020; 15 MS Brozzo (10021_CR123) 2012; 119 H Xu (10021_CR159) 2017; 14 C Xu (10021_CR168) 2013 AB Lassman (10021_CR91) 2019; 30 |
| References_xml | – volume: 11 start-page: 285 year: 2010 end-page: 295 ident: CR118 article-title: Predictions of the ADMET properties of candidate drug molecules utilizing different QSAR/QSPR modelling approaches publication-title: Curr Drug Metab doi: 10.2174/138920010791514306 – volume: 90 start-page: 629 year: 2017 end-page: 636 ident: CR133 article-title: Epidermal growth factor receptor (EGFR) structure-based bioactive pharmacophore models for identifying next-generation inhibitors against clinically relevant EGFR mutations publication-title: Chem Biol Drug Des doi: 10.1111/cbdd.12977 – volume: 18 start-page: 3 year: 2017 end-page: 9 ident: CR58 article-title: Glioblastoma multiforme: a review of its epidemiology and pathogenesis through clinical presentation and treatment publication-title: Asian Pac J Cancer Prev doi: 10.22034/APJCP.2017.18.1.3 – start-page: 661 year: 2019 end-page: 676 ident: CR114 article-title: Quantitative structure-activity relationship (QSAR): modeling approaches to biological applications publication-title: Encyclopedia of bioinformatics and computational biology doi: 10.1016/B978-0-12-809633-8.20197-0 – volume: 11 start-page: 1 year: 2021 end-page: 12 ident: CR69 article-title: Current immunotherapies for glioblastoma multiforme publication-title: Front Immunol doi: 10.3389/fimmu.2020.603911 – volume: 114 start-page: 97 year: 2007 end-page: 109 ident: CR7 article-title: The 2007 WHO classification of tumours of the central nervous system publication-title: Acta Neuropathol doi: 10.1007/s00401-007-0243-4 – volume: 30 start-page: 664 year: 2020 end-page: 678 ident: CR27 article-title: Pathology, diagnostics, and classification of medulloblastoma publication-title: Brain Pathol doi: 10.1111/bpa.12837 – volume: 15 start-page: 6 year: 2020 end-page: 8 ident: CR54 article-title: Revealing the epigenetic effect of temozolomide on glioblastoma cell lines in therapeutic conditions publication-title: PLoS ONE doi: 10.1371/journal.pone.0229534 – volume: 8 start-page: 1 year: 2018 end-page: 8 ident: CR70 article-title: Immune checkpoints and innovative therapies in glioblastoma publication-title: Front Oncol doi: 10.3389/fonc.2018.00464 – volume: 55 start-page: 3718 year: 2018 end-page: 3724 ident: CR47 article-title: BRAF mutation is associated with an improved survival in glioma—a systematic review and meta-analysis publication-title: Mol Neurobiol doi: 10.1007/s12035-017-0599-y – volume: 8 start-page: 40187 year: 2018 end-page: 40197 ident: CR139 article-title: Allosteric inhibition induces an open WPD-loop: a new avenue towards glioblastoma therapy publication-title: RSC Adv doi: 10.1039/C8RA08427K – volume: 36 start-page: 3499 year: 2015 end-page: 3509 ident: CR140 article-title: The effect of benzyl isothiocyanate and its computer-aided design derivants targeting alkylglycerone phosphate synthase on the inhibition of human glioma U87MG cell line publication-title: Tumor Biol doi: 10.1007/s13277-014-2986-6 – volume: 68 start-page: 59 year: 2021 end-page: 74 ident: CR99 article-title: Computer-aided drug repurposing for cancer therapy: approaches and opportunities to challenge anticancer targets publication-title: Semin Cancer Biol doi: 10.1016/j.semcancer.2019.09.023 – volume: 18 start-page: 417 year: 2016 end-page: 425 ident: CR191 article-title: Imaging patterns predict patient survival and molecular subtype in glioblastoma via machine learning techniques publication-title: Neuro Oncol doi: 10.1093/neuonc/nov127 – volume: 8 start-page: 44015 year: 2017 end-page: 44031 ident: CR60 article-title: Survival benefit of glioblastoma patients after FDA approval of temozolomide concomitant with radiation and bevacizumab: a population-based study publication-title: Oncotarget doi: 10.18632/oncotarget.17054 – volume: 3 start-page: 1 issue: NOV year: 2013 end-page: 7 ident: CR207 article-title: Potential applications of imaging and -guided radiotherapy for brain metastases and glioblastoma to improve patient quality of life publication-title: Front Oncol doi: 10.3389/fonc.2013.00284 – volume: 2012 start-page: 1 year: 2012 end-page: 4 ident: CR212 article-title: Purely cortical anaplastic ependymoma publication-title: Case Rep Oncol Med doi: 10.1155/2012/541431 – volume: 9 start-page: 1 year: 2020 end-page: 11 ident: CR38 article-title: O6-methylguanine-DNA methyltransferase (MGMT): challenges and new opportunities in glioma chemotherapy publication-title: Front Oncol doi: 10.3389/fonc.2019.01547 – volume: 13 start-page: 701 year: 2009 end-page: 718 ident: CR71 article-title: Glioblastoma multiforme: a review of therapeutic targets publication-title: Expert Opin Ther Targets doi: 10.1517/14728220902942348 – volume: 10 start-page: e00570 year: 2020 ident: CR121 article-title: Molecular docking studies, drug-likeness and in-silico ADMET prediction of some novel β-Amino alcohol grafted 1,4,5-trisubstituted 1,2,3-triazoles derivatives as elevators of p53 protein levels publication-title: Sci Afr doi: 10.1016/j.sciaf.2020.e00570 – volume: 76 start-page: 1 year: 2010 end-page: 9 ident: CR131 article-title: Targeting the dimerization of epidermal growth factor receptors with small-molecule inhibitors publication-title: Chem Biol Drug Des doi: 10.1111/j.1747-0285.2010.00986.x – volume: 94 start-page: 445 year: 2001 end-page: 453 ident: CR203 article-title: Magnetic source imaging of late evoked field responses to vowels: Toward an assessment of hemispheric dominance for language publication-title: J Neurosurg doi: 10.3171/jns.2001.94.3.0445 – volume: 9 start-page: 347 year: 2010 end-page: 358 ident: CR201 article-title: Functional MRI for radiotherapy of gliomas publication-title: Technol Cancer Res Treat doi: 10.1177/153303461000900405 – volume: 13 start-page: 582 year: 2006 end-page: 588 ident: CR128 article-title: Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents publication-title: Nat Struct Mol Biol doi: 10.1038/nsmb1105 – year: 2016 ident: CR195 article-title: Treatment of glioma using neuroArm surgical system publication-title: Biomed Res Int doi: 10.1155/2016/9734512 – volume: 123 start-page: 325 year: 2015 end-page: 339 ident: CR196 article-title: Awake craniotomy to maximize glioma resection: methods and technical nuances over a 27-year period publication-title: J Neurosurg doi: 10.3171/2014.10.JNS141520 – volume: 9 start-page: 703 year: 2012 end-page: 715 ident: CR157 article-title: The epidermal growth factor receptor as a therapeutic target in glioblastoma multiforme and other malignant neoplasms publication-title: Anticancer Agents Med Chem doi: 10.2174/187152009788680019 – volume: 71 start-page: 209 year: 2021 end-page: 249 ident: CR2 article-title: Global Cancer Statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 Countries publication-title: CA Cancer J Clin doi: 10.3322/caac.21660 – volume: 14 start-page: 683 year: 2001 end-page: 688 ident: CR6 article-title: Progenitor cells and glioma formation publication-title: Curr Opin Neurol doi: 10.1097/00019052-200112000-00002 – volume: 12 start-page: 769 year: 2017 end-page: 784 ident: CR115 article-title: The advancement of multidimensional QSAR for novel drug discovery—where are we headed? publication-title: Expert Opin Drug Discov – volume: 12 start-page: 675 year: 2010 end-page: 684 ident: CR158 article-title: Epidermal growth factor receptor in glioma: signal transduction, neuropathology, imaging, and radioresistance1 publication-title: Neoplasia doi: 10.1593/neo.10688 – volume: 82 start-page: 638 year: 2004 end-page: 655 ident: CR21 article-title: Pathology and molecular genetics of oligodendroglial tumors publication-title: J Mol Med doi: 10.1007/s00109-004-0565-9 – volume: 9 start-page: 1 year: 2018 end-page: 31 ident: CR206 article-title: Glioblastoma treatments: an account of recent industrial developments publication-title: Front Pharmacol doi: 10.3389/fphar.2018.00879 – volume: 38 start-page: 1 year: 2019 end-page: 14 ident: CR82 article-title: The third-generation EGFR inhibitor AZD9291 overcomes primary resistance by continuously blocking ERK signaling in glioblastoma publication-title: J Exp Clin Cancer Res doi: 10.1186/s13046-019-1235-7 – volume: 12 start-page: 1931 year: 2018 end-page: 1939 ident: CR141 article-title: Computer-aided drug design and inhibitive effect of a novel nitrogenous heterocyclic compound and its mechanism on glioma U251 cells and breast cancer MCF-7 cells publication-title: Drug Des Dev Ther doi: 10.2147/DDDT.S168130 – volume: 8 start-page: 1 year: 2020 end-page: 13 ident: CR52 article-title: A glioblastoma genomics primer for clinicians publication-title: Med Res Arch doi: 10.18103/mra.v8i2.2034 – volume: 27 start-page: 823 year: 2018 end-page: 829 ident: CR84 article-title: Dacomitinib: an investigational drug for the treatment of glioblastoma publication-title: Expert Opin Investig Drugs doi: 10.1080/13543784.2018.1528225 – volume: 44 start-page: 235 year: 2000 end-page: 249 ident: CR120 article-title: Drug-like properties and the causes of poor solubility and poor permeability publication-title: J Pharmacol Toxicol Methods doi: 10.1016/S1056-8719(00)00107-6 – volume: 5 start-page: 1103 year: 2013 end-page: 1119 ident: CR45 article-title: Emerging biomarkers in glioblastoma publication-title: Cancers (Basel) doi: 10.3390/cancers5031103 – volume: 63 start-page: 1612 year: 2020 end-page: 1623 ident: CR149 article-title: Structure-based design and identification of FT-2102 (Olutasidenib), a potent mutant-selective IDH1 inhibitor publication-title: J Med Chem doi: 10.1021/acs.jmedchem.9b01423 – volume: 10 start-page: 2589 year: 2015 end-page: 2597 ident: CR180 article-title: Discovery of inhibitors for the ether lipid-generating enzyme AGPS as anti-cancer agents publication-title: ACS Chem Biol doi: 10.1021/acschembio.5b00466 – volume: 18 start-page: 16 year: 2016 end-page: 26 ident: CR186 article-title: Isocitrate dehydrogenase mutations in gliomas publication-title: Neuro Oncol doi: 10.1093/neuonc/nov136 – year: 2019 ident: CR22 article-title: Incidence, mortality and outcome of meningiomas: a population-based study from Germany publication-title: Cancer Epidemiol doi: 10.1016/j.canep.2019.07.001 – volume: 25 start-page: 1 year: 2020 end-page: 15 ident: CR153 article-title: Structural basis of beneficial design for effective nicotinamide phosphoribosyltransferase inhibitors publication-title: Molecules doi: 10.3390/molecules25163633 – volume: 9 start-page: 1 year: 2011 end-page: 9 ident: CR104 article-title: Molecular dynamics simulations and drug discovery publication-title: BMC Biol doi: 10.1186/1741-7007-9-71 – volume: 4 start-page: 35 year: 2016 end-page: 51 ident: CR30 article-title: Chordoma: the quest for better treatment options publication-title: Oncol Ther doi: 10.1007/s40487-016-0016-0 – volume: 96 start-page: 1047 year: 2007 end-page: 1051 ident: CR79 article-title: Gefitinib in patients with progressive high-grade gliomas: a multicentre phase II study by Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO) publication-title: Br J Cancer doi: 10.1038/sj.bjc.6603669 – ident: CR162 – volume: 33 start-page: 1097 year: 2018 end-page: 1104 ident: CR92 article-title: Benzyl isothiocyanate inhibits human brain glioblastoma multiforme GBM 8401 cell xenograft tumor in nude mice in vivo publication-title: Environ Toxicol doi: 10.1002/tox.22581 – volume: 60 start-page: 2635 year: 2019 end-page: 2645 ident: CR181 article-title: Emerging drug profile: Krebs cycle and cancer: IDH mutations and therapeutic implications publication-title: Leuk Lymphoma doi: 10.1080/10428194.2019.1602260 – volume: 15 start-page: 1473 year: 2020 end-page: 1487 ident: CR116 article-title: Open access in silico tools to predict the ADMET profiling of drug candidates publication-title: Expert Opin Drug Discov doi: 10.1080/17460441.2020.1798926 – volume: 20 start-page: 22 year: 1957 end-page: 39 ident: CR23 article-title: The recurrence of intracranial meningiomas after surgical treatment publication-title: J Neurol Neurosurg Psychiatry doi: 10.1136/jnnp.20.1.22 – volume: 121 start-page: 91 year: 2015 end-page: 100 ident: CR89 article-title: Single agent efficacy of the VEGFR kinase inhibitor axitinib in preclinical models of glioblastoma publication-title: J Neurooncol doi: 10.1007/s11060-014-1612-1 – volume: 1 start-page: 97 year: 2006 end-page: 117 ident: CR16 article-title: Molecular pathology of malignant gliomas publication-title: Annu Rev Pathol doi: 10.1146/annurev.pathol.1.110304.100043 – volume: 9 start-page: 414 year: 2011 end-page: 427 ident: CR167 article-title: A review of VEGF/VEGFR-targeted therapeutics for recurrent glioblastoma publication-title: JNCCN J Natl Compr Cancer Netw doi: 10.6004/jnccn.2011.0038 – volume: 9 start-page: 1 year: 2019 end-page: 7 ident: CR183 article-title: Isocitrate dehydrogenase mutations in glioma: from basic discovery to therapeutics development publication-title: Front Oncol doi: 10.3389/fonc.2019.00506 – volume: 5 start-page: 102 year: 2012 end-page: 114 ident: CR55 article-title: Temozolomide: mechanisms of action, repair and resistance publication-title: Curr Mol Pharmacol doi: 10.2174/1874-470211205010102 – volume: 11 start-page: 101 year: 2020 end-page: 107 ident: CR77 article-title: Vorasidenib (AG-881): a first-in-class, brain-penetrant dual inhibitor of mutant IDH1 and 2 for treatment of glioma publication-title: ACS Med Chem Lett doi: 10.1021/acsmedchemlett.9b00509 – volume: 6 start-page: 96735 year: 2016 end-page: 96742 ident: CR147 article-title: Identification of a novel selective inhibitor of mutant isocitrate dehydrogenase 1 at allosteric site by docking-based virtual screening publication-title: RSC Adv doi: 10.1039/c6ra21617j – volume: 8 start-page: 44255 year: 2017 end-page: 44265 ident: CR144 article-title: Structure based discovery of clomifene as a potent inhibitor of cancer-associated mutant IDH1 publication-title: Oncotarget doi: 10.18632/oncotarget.17464 – volume: 27 start-page: 3229 year: 2019 end-page: 3236 ident: CR148 article-title: Discovery of DC_H31 as potential mutant IDH1 inhibitor through NADPH-based high throughput screening publication-title: Bioorg Med Chem doi: 10.1016/j.bmc.2019.05.040 – volume: 16 start-page: 1431 year: 2018 end-page: 1438 ident: CR143 article-title: Adme/toxicity prediction and antitumor activity of novel nitrogenous heterocyclic compounds designed by computer targeting of alkylglycerone phosphate synthase publication-title: Oncol Lett doi: 10.3892/ol.2018.8873 – volume: 27 start-page: 196 year: 1984 end-page: 201 ident: CR59 article-title: Antitumor Imidazotetrazines. 1. Synthesis and chemistry of 8-carbamoyl-3-(2-chloroethyl)imidazo[5, l-d]-l,2,3,5-tetrazin-4(3H)-one, a novel broad-spectrum antitumor agent publication-title: J Med Chem doi: 10.1021/jm00368a016 – volume: 15 start-page: 15994 year: 2014 end-page: 16011 ident: CR88 article-title: In silico discovery of potential VEGFR-2 inhibitors from natural derivatives for anti-angiogenesis therapy publication-title: Int J Mol Sci doi: 10.3390/ijms150915994 – start-page: 238 year: 2016 end-page: 240 ident: CR164 publication-title: Review: book reviews reviewed work (s): the common place of law stories from everyday life by Patricia doi: 10.1128/MCB.25.17.7734 – volume: 481 start-page: 227 year: 2000 end-page: 234 ident: CR14 article-title: Elevated expression of membrane type 1 metalloproteinase (MT1-MMP) in reactive astrocytes following neurodegeneration in mouse central nervous system publication-title: FEBS Lett doi: 10.1016/S0014-5793(00)02011-1 – volume: 25 start-page: 7734 year: 2005 end-page: 7742 ident: CR165 article-title: Epidermal growth factor receptor dimerization and activation require ligand-induced conformational changes in the dimer interface publication-title: Mol Cell Biol doi: 10.1128/mcb.25.17.7734-7742.2005 – volume: 5 start-page: 92 year: 2019 end-page: 97 ident: CR64 article-title: The side effects of chemotherapy in glioma publication-title: MNJ Malang Neurol J doi: 10.21776/ub.mnj.2019.005.02.9 – ident: CR208 – volume: 117 start-page: 379 year: 2014 end-page: 394 ident: CR24 article-title: Epidemiology and etiopathogenesis of pituitary adenomas publication-title: J Neurooncol doi: 10.1007/s11060-013-1354-5 – volume: 75 start-page: 20 year: 2020 end-page: 32 ident: CR189 article-title: Machine learning and glioma imaging biomarkers publication-title: Clin Radiol doi: 10.1016/j.crad.2019.07.001 – volume: 8 start-page: CNS43 year: 2019 ident: CR81 article-title: Clinical activity of the EGFR tyrosine kinase inhibitor osimertinib in EGFR-mutant glioblastoma publication-title: CNS Oncol doi: 10.2217/cns-2019-0014 – volume: 38 start-page: 3398 year: 2020 end-page: 3406 ident: CR96 article-title: Ivosidenib in isocitrate dehydrogenase 1-mutated advanced glioma publication-title: J Clin Oncol doi: 10.1200/JCO.19.03327 – volume: 4 start-page: 151 year: 2018 end-page: 165 ident: CR185 article-title: Metabolism, activity, and targeting of D- and L-2-hydroxyglutarates publication-title: Trends Cancer doi: 10.1016/j.trecan.2017.12.005 – volume: 14 start-page: 512 year: 2017 end-page: 516 ident: CR159 article-title: Epidermal growth factor receptor in glioblastoma (Review) publication-title: Oncol Lett doi: 10.3892/ol.2017.6221 – year: 2019 ident: CR98 article-title: Computational drug design methods—current and future perspectives publication-title: Silico Drug Des doi: 10.1016/b978-0-12-816125-8.00002-x – volume: 6 start-page: 100173 year: 2021 ident: CR28 article-title: How we treat medulloblastoma in adults publication-title: ESMO Open doi: 10.1016/j.esmoop.2021.100173 – year: 2013 ident: CR168 article-title: VEGF promotes proliferation of human glioblastoma multiforme stem-like cells through VEGF receptor 2 publication-title: Sci World J doi: 10.1155/2013/417413 – volume: 22 start-page: 101424 year: 2019 ident: CR137 article-title: Molecular docking and interactions between vascular endothelial growth factor (VEGF) receptors and phytochemicals: an in-silico study publication-title: Biocatal Agric Biotechnol doi: 10.1016/j.bcab.2019.101424 – year: 2017 ident: CR132 article-title: 2D-QSAR and 3D-QSAR analyses for EGFR inhibitors publication-title: Biomed Res Int doi: 10.1155/2017/4649191 – volume: 16 start-page: viii14 year: 2014 end-page: viii19 ident: CR161 article-title: Challenges to targeting epidermal growth factor receptor in glioblastoma: escape mechanisms and combinatorial treatment strategies publication-title: Neuro Oncol doi: 10.1093/neuonc/nou222 – volume: 16 start-page: 1365 year: 2014 end-page: 1372 ident: CR204 article-title: Navigated transcranial magnetic stimulation improves the treatment outcome in patients with brain tumors in motor eloquent locations publication-title: Neuro Oncol doi: 10.1093/neuonc/nou110 – volume: 18 start-page: 914 year: 2016 end-page: 918 ident: CR160 article-title: Epidermal growth factor receptor targeting and challenges in glioblastoma publication-title: Neuro Oncol doi: 10.1093/neuonc/nov319 – volume: 9 start-page: 1 year: 2018 end-page: 10 ident: CR197 article-title: Magnetic resonance spectroscopy, positron emission tomography and radiogenomics-Relevance to glioma publication-title: Front Neurol doi: 10.3389/fneur.2018.00033 – volume: 6 start-page: S85 year: 2015 end-page: S88 ident: CR48 article-title: Treatment of Gliomas: how did we get here? publication-title: Surg Neurol Int doi: 10.4103/2152-7806.151348 – volume: 35 start-page: 1 year: 2016 end-page: 9 ident: CR49 article-title: The comparison of clinical and biological characteristics between IDH1 and IDH2 mutations in gliomas publication-title: J Exp Clin Cancer Res doi: 10.1186/s13046-016-0362-7 – volume: 82 start-page: 656 year: 2004 end-page: 670 ident: CR18 article-title: Pathology and molecular genetics of astrocytic gliomas publication-title: J Mol Med doi: 10.1007/s00109-004-0564-x – volume: 20 start-page: 2681 year: 2019 end-page: 2692 ident: CR136 article-title: Identification of potent VEGF inhibitors for the clinical treatment of glioblastoma, a virtual screening approach publication-title: Asian Pac J Cancer Prev doi: 10.31557/APJCP.2019.20.9.2681 – volume: 15 start-page: 30 year: 2019 end-page: 40 ident: CR25 article-title: Functioning pituitary adenomas—current treatment options and emerging medical therapies publication-title: Eur Endocrinol doi: 10.17925/EE.2019.15.1.30 – volume: 22 start-page: 195 year: 2006 end-page: 201 ident: CR117 article-title: The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling publication-title: Bioinformatics doi: 10.1093/bioinformatics/bti770 – volume: 12 start-page: 1 year: 2020 end-page: 22 ident: CR171 article-title: Role of fibroblast growth factors receptors (FGFRs) in brain tumors, focus on astrocytoma and glioblastoma publication-title: Cancers (Basel) doi: 10.3390/cancers12123825 – volume: 6 start-page: 48 year: 2009 end-page: 51 ident: CR56 article-title: Temozolomide birth of a blockbuster publication-title: Chem World – volume: 20 start-page: 22799 year: 2015 end-page: 22832 ident: CR113 article-title: Pharmacophore models and pharmacophore-based virtual screening: concepts and applications exemplified on hydroxysteroid dehydrogenases publication-title: Molecules doi: 10.3390/molecules201219880 – volume: 15 start-page: 468 year: 2005 end-page: 484 ident: CR213 article-title: Intra-axial brain tumours publication-title: Eur Radiol doi: 10.1007/s00330-004-2555-2 – volume: 9 start-page: 1 year: 2020 end-page: 7 ident: CR29 article-title: Recent advances in understanding and managing chordomas: an update publication-title: F1000Research doi: 10.12688/f1000research.22440.1 – volume: 21 start-page: 65 year: 2018 end-page: 87 ident: CR106 article-title: Molecular docking: current advances and challenges publication-title: TIP Rev Espec en Ciencias Quim Biol – volume: 277 start-page: 46265 year: 2002 end-page: 46272 ident: CR122 article-title: Structure of the epidermal growth factor receptor kinase domain alone and in complex with a 4-anilinoquinazoline inhibitor publication-title: J Biol Chem doi: 10.1074/jbc.M207135200 – volume: 29 start-page: 159 year: 2008 end-page: 163 ident: CR26 article-title: Pineocytoma mimicking a pineal cyst on imaging: true diagnostic dilemma or a case of incomplete imaging? publication-title: Am J Neuroradiol doi: 10.3174/ajnr.A0750 – volume: 60 start-page: 4109 year: 2020 end-page: 4111 ident: CR109 article-title: New trends in virtual screening publication-title: J Chem Inf Model doi: 10.1021/acs.jcim.0c01009 – volume: 39 start-page: 415 year: 2019 end-page: 433 ident: CR138 article-title: Molecular dynamics guided insight, binding free energy calculations and pharmacophore-based virtual screening for the identification of potential VEGFR2 inhibitors publication-title: J Recept Signal Transduct doi: 10.1080/10799893.2019.1690509 – volume: 16 start-page: 565 year: 2012 end-page: 577 ident: CR179 article-title: Global profiling strategies for mapping dysregulated metabolic pathways in cancer publication-title: Cell Metab doi: 10.1016/j.cmet.2012.09.013 – volume: 3 start-page: 187 year: 2007 end-page: 197 ident: CR112 article-title: Pharmacophore modeling in drug discovery and development: an overview publication-title: Med Chem doi: 10.2174/157340607780059521 – volume: 1 start-page: 1 year: 2011 end-page: 12 ident: CR151 article-title: Virtual screening, identification and experimental testing of novel inhibitors of PBEF1/Visfatin/NMPRTase for glioma therapy publication-title: J Clin Bioinform doi: 10.1186/2043-9113-1-5 – year: 2016 ident: CR61 publication-title: Current standards of care in glioblastoma therapy doi: 10.1016/B978-0-323-47660-7.00006-9 – volume: 43 start-page: 29 year: 2019 end-page: 37 ident: CR156 article-title: The TICking clock of EGFR therapy resistance in glioblastoma: target independence or target compensation publication-title: Drug Resist Updat doi: 10.1016/j.drup.2019.04.002 – volume: 21 start-page: 1 year: 2020 end-page: 21 ident: CR50 article-title: Tumor cell invasion in glioblastoma publication-title: Int J Mol Sci doi: 10.3390/ijms21061932 – volume: 26 start-page: 551 year: 2019 end-page: 565 ident: CR63 article-title: A comprehensive review in improving delivery of small-molecule chemotherapeutic agents overcoming the blood-brain/brain tumor barriers for glioblastoma treatment publication-title: Drug Deliv doi: 10.1080/10717544.2019.1616235 – volume: 27 start-page: 3043 year: 2018 end-page: 3058 ident: CR31 article-title: Chordoma: a systematic review of the epidemiology and clinical prognostic factors predicting progression-free and overall survival publication-title: Eur Spine J doi: 10.1007/s00586-018-5764-0 – volume: 131 start-page: 803 year: 2016 end-page: 820 ident: CR35 article-title: The 2016 World Health Organization classification of tumors of the central nervous system: a summary publication-title: Acta Neuropathol doi: 10.1007/s00401-016-1545-1 – volume: 343 start-page: 342 year: 2012 end-page: 350 ident: CR125 article-title: Target binding properties and cellular activity of afatinib (BIBW 2992), an irreversible ErbB family blocker publication-title: J Pharmacol Exp Ther doi: 10.1124/jpet.112.197756 – volume: 35 start-page: 72 year: 2020 end-page: 84 ident: CR154 article-title: Design, synthesis and biological evaluation of novel 1H–1,2,4-triazole, benzothiazole and indazole-based derivatives as potent FGFR1 inhibitors viafragment-based virtual screening publication-title: J Enzyme Inhib Med Chem doi: 10.1080/14756366.2019.1673745 – volume: 28 start-page: 115217 year: 2020 ident: CR152 article-title: Identification of small-molecule urea derivatives as novel NAMPT inhibitors via pharmacophore-based virtual screening publication-title: Bioorg Med Chem doi: 10.1016/j.bmc.2019.115217 – volume: 18 start-page: 170 year: 2021 end-page: 186 ident: CR4 article-title: EANO guidelines on the diagnosis and treatment of diffuse gliomas of adulthood publication-title: Nat Rev Clin Oncol doi: 10.1038/s41571-020-00447-z – year: 2013 ident: CR12 article-title: The controversial role of microglia in malignant gliomas publication-title: Clin Dev Immunol doi: 10.1155/2013/285246 – year: 2015 ident: CR9 article-title: Glioma publication-title: Nat Rev Dis Prim doi: 10.1038/nrdp.2015.17 – volume: 7 start-page: 81 year: 2014 end-page: 92 ident: CR111 article-title: Pharmacophore modeling: advances, limitations, and current utility in drug discovery publication-title: J Receptor Ligand Channel Res doi: 10.2147/JRLCR.S46843 – volume: 109 start-page: 18281 year: 2012 end-page: 18289 ident: CR127 article-title: Molecular conformations, interactions, and properties associated with drug efficiency and clinical performance among VEGFR TK inhibitors publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.1207759109 – volume: 8 start-page: 13 year: 2020 end-page: 32 ident: CR10 article-title: The time has come for targeted therapies for AML: lights and shadows publication-title: Oncol Ther doi: 10.1007/s40487-019-00108-x – year: 2017 ident: CR105 article-title: Molecular docking: approaches, types, applications and basic challenges publication-title: J Anal Bioanal Tech doi: 10.4172/2155-9872.1000356 – volume: 102 start-page: 932 year: 2010 end-page: 941 ident: CR182 article-title: Isocitrate dehydrogenase 1 and 2 mutations in cancer: alterations at a crossroads of cellular metabolism publication-title: J Natl Cancer Inst doi: 10.1093/jnci/djq187 – volume: 14 start-page: 3 year: 2019 end-page: 17 ident: CR94 article-title: Enasidenib in the treatment of relapsed/refractory acute myeloid leukemia: an evidence-based review of its place in therapy publication-title: Core Evid doi: 10.2147/ce.s172912 – volume: 28 start-page: 34 year: 2020 end-page: 38 ident: CR130 article-title: In-silico molecular docking study of novel derivatives of erlotinib in glioma publication-title: Asia-Pac J Mol Biol Biotechnol doi: 10.35118/apjmbb.2020.028.1.04 – ident: CR210 – volume: 15 start-page: 4041 year: 2010 end-page: 4054 ident: CR163 article-title: Receptor-based virtual screening of EGFR kinase inhibitors from the NCI diversity database publication-title: Molecules doi: 10.3390/molecules15064041 – volume: 56 start-page: 843 year: 2016 end-page: 853 ident: CR78 article-title: Probing the druggability limits for enzymes of the NAD biosynthetic network in glioma publication-title: J Chem Inf Model doi: 10.1021/acs.jcim.5b00733 – volume: 37 start-page: 167 year: 2015 end-page: 183 ident: CR51 article-title: Current evidence of temozolomide and bevacizumab in treatment of gliomas publication-title: Neurol Res doi: 10.1179/1743132814Y.0000000423 – year: 2018 ident: CR5 article-title: The treatment of gliomas in adulthood publication-title: Dtsch Arztebl Int doi: 10.3238/arztebl.2018.0356 – volume: 2 start-page: 1563 year: 2010 end-page: 1576 ident: CR178 article-title: Protein tyrosine phosphatases as drug targets: strategies and challenges of inhibitor development publication-title: Futur Med Chem doi: 10.4155/fmc.10.241 – volume: 30 start-page: 21 year: 2019 end-page: 22 ident: CR91 article-title: OS10.6 Infigratinib (BGJ398) in patients with recurrent gliomas with fibroblast growth factor receptor (FGFR) alterations: a multicenter phase II study publication-title: Neuro Oncol doi: 10.1093/neuonc/noz126.072 – volume: 8 start-page: 1 year: 2018 end-page: 11 ident: CR202 article-title: Diffusion weighted/tensor imaging, functional MRI and perfusion weighted imaging in glioblastoma-foundations and future publication-title: Front Neurol doi: 10.3389/fneur.2017.00660 – volume: 37 start-page: 1 year: 2018 end-page: 19 ident: CR86 article-title: Lycorine inhibits glioblastoma multiforme growth through EGFR suppression publication-title: J Exp Clin Cancer Res doi: 10.1186/s13046-018-0785-4 – volume: 8 start-page: 715 year: 2019 ident: CR73 article-title: Fibroblast growth factor receptor functions in glioblastoma publication-title: Cells doi: 10.3390/cells8070715 – volume: 16 start-page: 973 year: 2012 end-page: 984 ident: CR72 article-title: Therapeutic targeting of VEGF in the treatment of glioblastoma publication-title: Expert Opin Ther Targets doi: 10.1517/14728222.2012.711817 – volume: 110 start-page: 14912 year: 2013 end-page: 14917 ident: CR76 article-title: Ether lipid generating enzyme AGPS alters the balance of structural and signaling lipids to fuel cancer pathogenicity publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.1310894110 – volume: 112 start-page: 837 year: 2020 end-page: 847 ident: CR192 article-title: Glioma stages prediction based on machine learning algorithm combined with protein-protein interaction networks publication-title: Genomics doi: 10.1016/j.ygeno.2019.05.024 – volume: 2 start-page: 1 year: 2019 end-page: 13 ident: CR194 article-title: Novel approaches for glioblastoma treatment: focus on tumor heterogeneity, treatment resistance, and computational tools publication-title: Cancer Rep doi: 10.1002/cnr2.1220 – volume: 15 start-page: 1 year: 2015 end-page: 16 ident: CR209 article-title: Transcriptional profiles of pilocytic astrocytoma are related to their three different locations, but not to radiological tumor features publication-title: BMC Cancer doi: 10.1186/s12885-015-1810-z – volume: 8 start-page: 1 year: 2018 end-page: 19 ident: CR66 article-title: A critical overview of targeted therapies for glioblastoma publication-title: Front Oncol doi: 10.3389/fonc.2018.00419 – volume: 20 start-page: 1 year: 2020 end-page: 7 ident: CR1 article-title: Prognostic factors of patients with Gliomas—an analysis on 335 patients with Glioblastoma and other forms of Gliomas publication-title: BMC Cancer doi: 10.1186/s12885-019-6511-6 – volume: 10 start-page: 240 year: 2010 end-page: 247 ident: CR36 article-title: Ependymomas in adults publication-title: Curr Neurol Neurosci Rep doi: 10.1007/s11910-010-0109-3 – volume: 24 start-page: 180 year: 2018 end-page: 186 ident: CR68 article-title: Bevacizumab and glioblastoma past, present, and future directions publication-title: Cancer J (United States) doi: 10.1097/ppo.0000000000000326 – volume: 344 start-page: 1396 year: 2014 end-page: 1401 ident: CR176 article-title: Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma publication-title: Science doi: 10.1126/science.1254257 – volume: 19 start-page: 1325 year: 2019 ident: CR100 article-title: Turning to computer-aided drug design in the treatment of diffuse large B-cell lymphoma: has it been helpful? publication-title: Anticancer Agents Med Chem doi: 10.2174/1871520619666190405111526 – year: 2019 ident: CR95 article-title: Mutant isocitrate dehydrogenase inhibitors as targeted cancer therapeutics publication-title: Front Oncol doi: 10.3389/fonc.2019.00417 – volume: 134 start-page: 505 year: 2017 end-page: 512 ident: CR42 article-title: Molecular markers in glioma publication-title: J Neurooncol doi: 10.1007/s11060-017-2379-y – volume: 28 start-page: 388 year: 2018 end-page: 393 ident: CR146 article-title: Identification of novel allosteric inhibitors of mutant isocitrate dehydrogenase 1 by cross docking-based virtual screening publication-title: Bioorg Med Chem Lett doi: 10.1016/j.bmcl.2017.12.030 – volume: 20 start-page: 2839 year: 2013 end-page: 2860 ident: CR108 article-title: Virtual screening strategies in drug discovery: a critical review publication-title: Curr Med Chem doi: 10.2174/09298673113209990001 – volume: 11 start-page: 1 year: 2020 end-page: 11 ident: CR145 article-title: Discovery of novel IDH1 inhibitor through comparative structure- based virtual screening publication-title: Front Pharmacol doi: 10.3389/fphar.2020.579768 – volume: 79 start-page: 604 year: 2016 end-page: 611 ident: CR199 article-title: Intraoperative probe-based confocal laser endomicroscopy in surgery and stereotactic biopsy of low-grade and high-grade gliomas: a feasibility study in humans publication-title: Neurosurgery doi: 10.1227/NEU.0000000000001365 – volume: 8 start-page: 37 year: 2015 ident: CR103 article-title: Molecular dynamics simulations: advances and applications publication-title: Adv Appl Bioinform Chem – year: 2012 ident: CR200 article-title: The role of intraoperative magnetic resonance imaging in glioma surgery publication-title: Surg Neurol Int doi: 10.4103/2152-7806.103029 – volume: 9 start-page: 646 year: 2002 end-page: 652 ident: CR101 article-title: Molecular dynamics simulations of biomolecules publication-title: Nat Struct Biol doi: 10.1038/nsb0902-646 – volume: 9 start-page: 1 year: 2018 end-page: 16 ident: CR102 article-title: Bridging molecular docking to molecular dynamics in exploring ligand-protein recognition process: an overview publication-title: Front Pharmacol doi: 10.3389/fphar.2018.00923 – year: 2016 ident: CR93 article-title: Inhibitor of nicotinamide phosphoribosyltransferase sensitizes glioblastoma cells to temozolomide via activating ROS/JNK signaling pathway publication-title: Biomed Res Int doi: 10.1155/2016/1450843 – volume: 28 start-page: 2817 year: 2010 end-page: 2823 ident: CR90 article-title: Phase II study of cediranib, an oral pan-vascular endothelial growth factor receptor tyrosine kinase inhibitor, in patients with recurrent glioblastoma publication-title: J Clin Oncol doi: 10.1200/JCO.2009.26.3988 – volume: 20 start-page: 300211 year: 2020 ident: CR75 article-title: Effect of alkylglycerone phosphate synthase on the expression levels of lncRNAs in glioma cells and its functional prediction publication-title: Oncol Lett doi: 10.3892/ol.2020.11927 – volume: 58 start-page: 405 year: 2018 end-page: 421 ident: CR62 article-title: Potential strategies overcoming the temozolomide resistance for glioblastoma publication-title: Neurol Med Chir (Tokyo) doi: 10.2176/nmc.ra.2018-0141 – volume: 12 start-page: 727 year: 2017 ident: CR65 article-title: Tumor recurrence in a glioblastoma patient after discontinuation of prolonged temozolomide treatment publication-title: Asian J Neurosurg doi: 10.4103/ajns.ajns_39_15 – volume: 37 start-page: 61 year: 2016 end-page: 69 ident: CR11 article-title: The role of astrocytes in the progression of brain cancer: complicating the picture of the tumor microenvironment publication-title: Tumor Biol doi: 10.1007/s13277-015-4242-0 – volume: 7 start-page: 478 year: 2017 end-page: 493 ident: CR129 article-title: AG-221, a first-in-class therapy targeting acute myeloid leukemia harboring oncogenic IDH2 mutations publication-title: Cancer Discov doi: 10.1158/2159-8290.CD-16-1034 – volume: 12 start-page: 383 year: 2012 end-page: 394 ident: CR8 article-title: The cellular origin for malignant glioma and prospects for clinical advancements publication-title: Expert Rev Mol Diagn doi: 10.1586/erm.12.30 – volume: 23 start-page: 767 year: 2018 ident: CR107 article-title: Computational simulation studies on the binding selectivity of 1-(1H-Benzimidazol-5-yl)-5-aminopyrazoles in complexes with FGFR1 and FGFR4 publication-title: Molecules doi: 10.3390/molecules23040767 – volume: 32 start-page: 372 year: 2013 end-page: 380 ident: CR15 article-title: Review: molecular mechanism of microglia stimulated glioblastoma invasion publication-title: Matrix Biol doi: 10.1016/j.matbio.2013.07.008 – volume: 2 start-page: 1 year: 2019 end-page: 15 ident: CR190 article-title: Machine learning approaches to study glioblastoma: a review of the last decade of applications publication-title: Cancer Rep doi: 10.1002/cnr2.1226 – volume: 42 start-page: 963 year: 2019 end-page: 972 ident: CR187 article-title: NAMPT: a potential prognostic and therapeutic biomarker in patients with glioblastoma publication-title: Oncol Rep doi: 10.3892/or.2019.7227 – volume: 17 start-page: 225 year: 2010 end-page: 234 ident: CR40 article-title: The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate publication-title: Cancer Cell doi: 10.1016/j.ccr.2010.01.020 – volume: 192 start-page: 539 year: 2015 end-page: 544 ident: CR126 article-title: Binding mode of the breakthrough inhibitor AZD9291 to epidermal growth factor receptor revealed publication-title: J Struct Biol doi: 10.1016/j.jsb.2015.10.018 – volume: 10 start-page: 1663 year: 2019 end-page: 1674 ident: CR177 article-title: The expression, functions, interactions and prognostic values of PTPRZ1: a review and bioinformatic analysis publication-title: J Cancer doi: 10.7150/jca.28231 – volume: 20 start-page: 432 year: 2018 end-page: 442 ident: CR83 article-title: A pre-clinical assessment of the Pan-ERBB inhibitor dacomitinib in pediatric and adult brain tumors publication-title: Neoplasia (United States) doi: 10.1016/j.neo.2018.02.004 – year: 2018 ident: CR119 publication-title: Computer-aided prediction of pharmacokinetic (ADMET) properties doi: 10.1016/B978-0-12-814421-3.00021-X – volume: 53 start-page: LP2272 year: 1993 end-page: LP2278 ident: CR173 article-title: Increased expression of specific protein tyrosine phosphatases in human breast epithelial cells neoplastically transformed by the Neu oncogene publication-title: Cancer Res – volume: 20 start-page: VII17 year: 2018 end-page: VII26 ident: CR41 article-title: Updates in prognostic markers for gliomas publication-title: Neuro Oncol doi: 10.1093/neuonc/noy158 – volume: 21 start-page: 2787 year: 2003 end-page: 2799 ident: CR80 article-title: Status of epidermal growth factor receptor antagonists in the biology and treatment of cancer publication-title: J Clin Oncol doi: 10.1200/JCO.2003.01.504 – volume: 119 start-page: 1781 year: 2012 end-page: 1788 ident: CR123 article-title: Thermodynamic and structural description of allosterically regulated VEGFR-2 dimerization publication-title: Blood doi: 10.1182/blood-2011-11-390922 – volume: 41 start-page: 1723 year: 2016 end-page: 1731 ident: CR20 article-title: Expression and prognostic significance of p53 in glioma patients: a meta-analysis publication-title: Neurochem Res doi: 10.1007/s11064-016-1888-y – volume: 21 start-page: 2683 year: 2007 end-page: 2710 ident: CR17 article-title: Malignant astrocytic glioma: genetics, biology, and paths to treatment publication-title: Genes Dev doi: 10.1101/gad.1596707 – volume: 8 start-page: 4103 year: 2017 ident: CR19 article-title: A simplified overview of WHO classification update publication-title: J Neurosci Rural Pract doi: 10.4103/jnrp.jnrp – volume: 7 start-page: 1 year: 2017 end-page: 8 ident: CR43 article-title: The role of ATRX in glioma biology publication-title: Front Oncol doi: 10.3389/fonc.2017.00236 – volume: 33 start-page: 852 year: 2012 end-page: 857 ident: CR211 article-title: Imaging characteristics of oligodendrogliomas that predict grade publication-title: Am J Neuroradiol doi: 10.3174/ajnr.A2895 – volume: 17 start-page: 3296 year: 2018 end-page: 3307 ident: CR97 article-title: Recent updates on computer-aided drug discovery: time for a paradigm shift publication-title: Curr Top Med Chem doi: 10.2174/1568026618666180101163651 – volume: 12 start-page: 4815 year: 2019 end-page: 4839 ident: CR134 article-title: Pharmacophore modeling, 3D-QSAR, docking and ADME prediction of quinazoline based EGFR inhibitors publication-title: Arab J Chem doi: 10.1016/j.arabjc.2016.09.019 – volume: 23 start-page: 35 year: 1997 end-page: 61 ident: CR57 article-title: Temozolomide: a review of its discovery, chemical properties, pre-clinical development and clinical trials publication-title: Cancer Treat Rev doi: 10.1016/S0305-7372(97)90019-0 – volume: 7 start-page: 1 year: 2017 end-page: 11 ident: CR166 article-title: Vascular endothelial growth factor, irradiation, and axitinib have diverse effects on motility and proliferation of glioblastoma multiforme cells publication-title: Front Oncol doi: 10.3389/fonc.2017.00182 – volume: 7 start-page: 1 year: 2020 end-page: 13 ident: CR39 article-title: Current opinion on molecular characterization for GBM classification in guiding clinical diagnosis, prognosis, and therapy publication-title: Front Mol Biosci doi: 10.3389/fmolb.2020.562798 – volume: 103 start-page: 325 year: 2011 end-page: 332 ident: CR87 article-title: Phase I trial with biomarker studies of vatalanib (PTK787) in patients with newly diagnosed glioblastoma treated with enzyme inducing anti-epileptic drugs and standard radiation and temozolomide publication-title: J Neurooncol doi: 10.1007/s11060-010-0390-7 – volume: 5 start-page: 1 year: 2019 end-page: 7 ident: CR205 article-title: Current status and potential application of navigated transcranial magnetic stimulation in neurosurgery: a literature review publication-title: Chinese Neurosurg J doi: 10.1186/s41016-019-0159-6 – year: 2017 ident: CR32 article-title: Surgical treatment of cerebellar hemangioblastomas publication-title: Surg Neurol Int doi: 10.4103/sni.sni_490_16 – volume: 14 start-page: 1131 year: 2009 end-page: 1138 ident: CR67 article-title: FDA Drug approval summary: bevacizumab (Avastin®) as treatment of recurrent glioblastoma multiforme publication-title: Oncologist doi: 10.1634/theoncologist.2009-0121 – volume: 23 start-page: 1531 year: 2017 end-page: 1547 ident: CR37 article-title: 2016 World Health Organization classification of central nervous system tumors publication-title: Contin Lifelong Learn Neurol doi: 10.1212/CON.0000000000000536 – volume: 16 start-page: 861 year: 2019 ident: CR150 article-title: Identification of new inhibitors of mutant isocitrate dehydrogenase 2 through molecular similarty-based virtual screening publication-title: Lett Drug Des Discov doi: 10.2174/1570180815666180808094432 – volume: 62 start-page: 1265 year: 2003 end-page: 1275 ident: CR175 article-title: Expression and function of the receptor protein tyrosine phosphatase zeta and its ligand pleiotrophin in human astrocytomas publication-title: J Neuropathol Exp Neurol doi: 10.1093/jnen/62.12.1265 – volume: 15 start-page: 3219 year: 2014 end-page: 3226 ident: CR34 article-title: Alkylglyceronephosphate synthase (AGPS) alters lipid signaling pathways and supports chemotherapy resistance of glioma and hepatic carcinoma cell lines publication-title: Asian Pac J Cancer Prev doi: 10.7314/APJCP.2014.15.7.3219 – volume: 20 start-page: 1375 year: 2019 ident: CR110 article-title: The light and dark sides of virtual screening: what is there to know? publication-title: Int J Mol Sci doi: 10.3390/ijms20061375 – volume: 38 start-page: 1 year: 2019 end-page: 13 ident: CR85 article-title: Afatinib and Temozolomide combination inhibits tumorigenesis by targeting EGFRvIII-cMet signaling in glioblastoma cells publication-title: J Exp Clin Cancer Res doi: 10.1186/s13046-019-1264-2 – volume: 7 start-page: 833 year: 2006 end-page: 846 ident: CR172 article-title: Protein tyrosine phosphatases: from genes, to function, to disease publication-title: Nat Rev Mol Cell Biol doi: 10.1038/nrm2039 – volume: 40 start-page: 1299 year: 2019 end-page: 1307 ident: CR184 article-title: Friend or foe-IDH1 mutations in glioma 10 years on publication-title: Carcinogenesis doi: 10.1093/carcin/bgz134 – volume: 8 start-page: 16052 year: 2017 end-page: 16074 ident: CR169 article-title: Inhibition of the fibroblast growth factor receptor (FGFR) pathway: the current landscape and barriers to clinical application publication-title: Oncotarget doi: 10.18632/oncotarget.14109 – year: 2015 ident: CR198 article-title: Detection of human brain cancer infiltration ex vivo and in vivo using quantitative optical coherence tomography publication-title: Sci Transl Med doi: 10.1126/scitranslmed.3010611 – volume: 8 start-page: 235 year: 2018 end-page: 240 ident: CR142 article-title: Computer-aided design of temozolomide derivatives based on alkylglycerone phosphate synthase structure with isothiocyanate and their pharmacokinetic/toxicity prediction and anti-tumor activity in vitro publication-title: Biomed Rep doi: 10.3892/br.2018.1051 – volume: 3 start-page: 37 year: 2014 end-page: 47 ident: CR3 article-title: Symptom management and quality of life in glioma patients publication-title: CNS Oncol doi: 10.2217/cns.13.65 – volume: 7 start-page: 1 year: 2017 end-page: 17 ident: CR124 article-title: Targeting PTPRZ inhibits stem cell-like properties and tumorigenicity in glioblastoma cells publication-title: Sci Rep doi: 10.1038/s41598-017-05931-8 – volume: 14 start-page: 958 year: 2012 end-page: 978 ident: CR13 article-title: The molecular profile of microglia under the influence of glioma publication-title: Neuro Oncol doi: 10.1093/neuonc/nos116 – volume: 134 start-page: 219 year: 2016 end-page: 234 ident: CR53 article-title: Complications from radiotherapy publication-title: Handb Clin Neurol doi: 10.1016/B978-0-12-802997-8.00013-X – volume: 3 start-page: 95 year: 2015 ident: CR33 article-title: Beyond the World Health Organization grading of infiltrating gliomas: advances in the molecular genetics of glioma classification publication-title: Ann Transl Med doi: 10.3978/j.issn.2305-5839.2015.03.57 – volume: 26 start-page: 67 year: 2000 end-page: 73 ident: CR44 article-title: The challenge of p53 as prognostic and predictive factor in gliomas publication-title: Cancer Treat Rev doi: 10.1053/ctrv.1999.0145 – volume: 22 start-page: 6661 year: 2003 end-page: 6668 ident: CR174 article-title: A role for receptor tyrosine phosphatase zeta in glioma cell migration publication-title: Oncogene doi: 10.1038/sj.onc.1206763 – volume: 269 start-page: 718 year: 2000 end-page: 725 ident: CR46 article-title: Expression of p16(INK4A) induces dominant suppression of glioblastoma growth in situ through necrosis and cell cycle arrest publication-title: Biochem Biophys Res Commun doi: 10.1006/bbrc.2000.2339 – volume: 26 start-page: 425 year: 2015 end-page: 449 ident: CR170 article-title: Functions of fibroblast growth factor receptors in cancer defined by novel translocations and mutations publication-title: Cytokine Growth Factor Rev doi: 10.1016/j.cytogfr.2015.03.003 – volume: 15 start-page: 420 year: 2013 end-page: 434 ident: CR155 article-title: Epidermal growth factor receptor as a therapeutic target in glioblastoma publication-title: Neuro Mol Med doi: 10.1007/s12017-013-8229-y – year: 2018 ident: CR193 article-title: MRI to MGMT: predicting methylation status in glioblastoma patients using convolutional recurrent neural networks publication-title: Pac Symp Biocomput doi: 10.1142/9789813235533_0031 – volume: 5 start-page: 18662 year: 2020 end-page: 18674 ident: CR135 article-title: 2D-QSAR modeling and molecular docking studies on 1 H-Pyrazole-1-carbothioamide derivatives as EGFR kinase inhibitors publication-title: ACS Omega doi: 10.1021/acsomega.0c01323 – volume: 26 start-page: 2920 year: 2016 end-page: 2926 ident: CR188 article-title: Application of virtual screening to the discovery of novel nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with potential for the treatment of cancer and axonopathies publication-title: Bioorg Med Chem Lett doi: 10.1016/j.bmcl.2016.04.039 – volume: 119 start-page: 157 year: 2010 end-page: 175 ident: CR74 article-title: Protein tyrosine phosphatases in glioma biology publication-title: Acta Neuropathol doi: 10.1007/s00401-009-0614-0 – volume: 43 start-page: 29 year: 2019 ident: 10021_CR156 publication-title: Drug Resist Updat doi: 10.1016/j.drup.2019.04.002 – volume: 28 start-page: 115217 year: 2020 ident: 10021_CR152 publication-title: Bioorg Med Chem doi: 10.1016/j.bmc.2019.115217 – volume: 2012 start-page: 1 year: 2012 ident: 10021_CR212 publication-title: Case Rep Oncol Med doi: 10.1155/2012/541431 – volume: 56 start-page: 843 year: 2016 ident: 10021_CR78 publication-title: J Chem Inf Model doi: 10.1021/acs.jcim.5b00733 – volume: 82 start-page: 656 year: 2004 ident: 10021_CR18 publication-title: J Mol Med doi: 10.1007/s00109-004-0564-x – year: 2018 ident: 10021_CR193 publication-title: Pac Symp Biocomput doi: 10.1142/9789813235533_0031 – volume: 7 start-page: 478 year: 2017 ident: 10021_CR129 publication-title: Cancer Discov doi: 10.1158/2159-8290.CD-16-1034 – volume: 23 start-page: 767 year: 2018 ident: 10021_CR107 publication-title: Molecules doi: 10.3390/molecules23040767 – volume: 9 start-page: 1 year: 2018 ident: 10021_CR102 publication-title: Front Pharmacol doi: 10.3389/fphar.2018.00923 – volume: 2 start-page: 1563 year: 2010 ident: 10021_CR178 publication-title: Futur Med Chem doi: 10.4155/fmc.10.241 – volume: 26 start-page: 425 year: 2015 ident: 10021_CR170 publication-title: Cytokine Growth Factor Rev doi: 10.1016/j.cytogfr.2015.03.003 – volume: 6 start-page: 100173 year: 2021 ident: 10021_CR28 publication-title: ESMO Open doi: 10.1016/j.esmoop.2021.100173 – volume: 12 start-page: 675 year: 2010 ident: 10021_CR158 publication-title: Neoplasia doi: 10.1593/neo.10688 – volume: 22 start-page: 101424 year: 2019 ident: 10021_CR137 publication-title: Biocatal Agric Biotechnol doi: 10.1016/j.bcab.2019.101424 – volume: 42 start-page: 963 year: 2019 ident: 10021_CR187 publication-title: Oncol Rep doi: 10.3892/or.2019.7227 – volume: 62 start-page: 1265 year: 2003 ident: 10021_CR175 publication-title: J Neuropathol Exp Neurol doi: 10.1093/jnen/62.12.1265 – volume: 14 start-page: 512 year: 2017 ident: 10021_CR159 publication-title: Oncol Lett doi: 10.3892/ol.2017.6221 – volume: 1 start-page: 97 year: 2006 ident: 10021_CR16 publication-title: Annu Rev Pathol doi: 10.1146/annurev.pathol.1.110304.100043 – start-page: 661 volume-title: Encyclopedia of bioinformatics and computational biology year: 2019 ident: 10021_CR114 doi: 10.1016/B978-0-12-809633-8.20197-0 – volume: 27 start-page: 3229 year: 2019 ident: 10021_CR148 publication-title: Bioorg Med Chem doi: 10.1016/j.bmc.2019.05.040 – volume: 55 start-page: 3718 year: 2018 ident: 10021_CR47 publication-title: Mol Neurobiol doi: 10.1007/s12035-017-0599-y – volume: 5 start-page: 92 year: 2019 ident: 10021_CR64 publication-title: MNJ Malang Neurol J doi: 10.21776/ub.mnj.2019.005.02.9 – volume: 33 start-page: 1097 year: 2018 ident: 10021_CR92 publication-title: Environ Toxicol doi: 10.1002/tox.22581 – volume: 71 start-page: 209 year: 2021 ident: 10021_CR2 publication-title: CA Cancer J Clin doi: 10.3322/caac.21660 – volume: 16 start-page: viii14 year: 2014 ident: 10021_CR161 publication-title: Neuro Oncol doi: 10.1093/neuonc/nou222 – volume: 8 start-page: 1 year: 2018 ident: 10021_CR202 publication-title: Front Neurol doi: 10.3389/fneur.2017.00660 – volume: 344 start-page: 1396 year: 2014 ident: 10021_CR176 publication-title: Science doi: 10.1126/science.1254257 – volume: 18 start-page: 417 year: 2016 ident: 10021_CR191 publication-title: Neuro Oncol doi: 10.1093/neuonc/nov127 – volume: 21 start-page: 2683 year: 2007 ident: 10021_CR17 publication-title: Genes Dev doi: 10.1101/gad.1596707 – volume: 12 start-page: 1931 year: 2018 ident: 10021_CR141 publication-title: Drug Des Dev Ther doi: 10.2147/DDDT.S168130 – volume: 27 start-page: 3043 year: 2018 ident: 10021_CR31 publication-title: Eur Spine J doi: 10.1007/s00586-018-5764-0 – volume: 37 start-page: 167 year: 2015 ident: 10021_CR51 publication-title: Neurol Res doi: 10.1179/1743132814Y.0000000423 – volume: 17 start-page: 3296 year: 2018 ident: 10021_CR97 publication-title: Curr Top Med Chem doi: 10.2174/1568026618666180101163651 – volume: 15 start-page: 420 year: 2013 ident: 10021_CR155 publication-title: Neuro Mol Med doi: 10.1007/s12017-013-8229-y – year: 2018 ident: 10021_CR5 publication-title: Dtsch Arztebl Int doi: 10.3238/arztebl.2018.0356 – volume: 18 start-page: 914 year: 2016 ident: 10021_CR160 publication-title: Neuro Oncol doi: 10.1093/neuonc/nov319 – year: 2017 ident: 10021_CR105 publication-title: J Anal Bioanal Tech doi: 10.4172/2155-9872.1000356 – volume: 90 start-page: 629 year: 2017 ident: 10021_CR133 publication-title: Chem Biol Drug Des doi: 10.1111/cbdd.12977 – volume: 14 start-page: 3 year: 2019 ident: 10021_CR94 publication-title: Core Evid doi: 10.2147/ce.s172912 – volume: 16 start-page: 1365 year: 2014 ident: 10021_CR204 publication-title: Neuro Oncol doi: 10.1093/neuonc/nou110 – volume: 38 start-page: 3398 year: 2020 ident: 10021_CR96 publication-title: J Clin Oncol doi: 10.1200/JCO.19.03327 – volume: 8 start-page: 715 year: 2019 ident: 10021_CR73 publication-title: Cells doi: 10.3390/cells8070715 – volume: 12 start-page: 4815 year: 2019 ident: 10021_CR134 publication-title: Arab J Chem doi: 10.1016/j.arabjc.2016.09.019 – volume: 3 start-page: 187 year: 2007 ident: 10021_CR112 publication-title: Med Chem doi: 10.2174/157340607780059521 – volume: 134 start-page: 219 year: 2016 ident: 10021_CR53 publication-title: Handb Clin Neurol doi: 10.1016/B978-0-12-802997-8.00013-X – volume: 94 start-page: 445 year: 2001 ident: 10021_CR203 publication-title: J Neurosurg doi: 10.3171/jns.2001.94.3.0445 – volume: 109 start-page: 18281 year: 2012 ident: 10021_CR127 publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.1207759109 – volume: 8 start-page: 40187 year: 2018 ident: 10021_CR139 publication-title: RSC Adv doi: 10.1039/C8RA08427K – volume: 8 start-page: 1 year: 2018 ident: 10021_CR70 publication-title: Front Oncol doi: 10.3389/fonc.2018.00464 – volume: 32 start-page: 372 year: 2013 ident: 10021_CR15 publication-title: Matrix Biol doi: 10.1016/j.matbio.2013.07.008 – volume: 23 start-page: 35 year: 1997 ident: 10021_CR57 publication-title: Cancer Treat Rev doi: 10.1016/S0305-7372(97)90019-0 – volume: 27 start-page: 823 year: 2018 ident: 10021_CR84 publication-title: Expert Opin Investig Drugs doi: 10.1080/13543784.2018.1528225 – volume: 26 start-page: 2920 year: 2016 ident: 10021_CR188 publication-title: Bioorg Med Chem Lett doi: 10.1016/j.bmcl.2016.04.039 – ident: 10021_CR208 doi: 10.1109/SCEECS.2014.6804439 – volume: 15 start-page: 6 year: 2020 ident: 10021_CR54 publication-title: PLoS ONE doi: 10.1371/journal.pone.0229534 – volume: 53 start-page: LP2272 year: 1993 ident: 10021_CR173 publication-title: Cancer Res – volume: 8 start-page: 1 year: 2020 ident: 10021_CR52 publication-title: Med Res Arch doi: 10.18103/mra.v8i2.2034 – volume: 343 start-page: 342 year: 2012 ident: 10021_CR125 publication-title: J Pharmacol Exp Ther doi: 10.1124/jpet.112.197756 – volume: 103 start-page: 325 year: 2011 ident: 10021_CR87 publication-title: J Neurooncol doi: 10.1007/s11060-010-0390-7 – volume: 38 start-page: 1 year: 2019 ident: 10021_CR82 publication-title: J Exp Clin Cancer Res doi: 10.1186/s13046-019-1235-7 – volume: 35 start-page: 72 year: 2020 ident: 10021_CR154 publication-title: J Enzyme Inhib Med Chem doi: 10.1080/14756366.2019.1673745 – volume: 30 start-page: 664 year: 2020 ident: 10021_CR27 publication-title: Brain Pathol doi: 10.1111/bpa.12837 – volume: 11 start-page: 285 year: 2010 ident: 10021_CR118 publication-title: Curr Drug Metab doi: 10.2174/138920010791514306 – volume: 11 start-page: 1 year: 2021 ident: 10021_CR69 publication-title: Front Immunol doi: 10.3389/fimmu.2020.603911 – year: 2017 ident: 10021_CR132 publication-title: Biomed Res Int doi: 10.1155/2017/4649191 – volume: 4 start-page: 151 year: 2018 ident: 10021_CR185 publication-title: Trends Cancer doi: 10.1016/j.trecan.2017.12.005 – volume: 20 start-page: 2681 year: 2019 ident: 10021_CR136 publication-title: Asian Pac J Cancer Prev doi: 10.31557/APJCP.2019.20.9.2681 – volume: 18 start-page: 3 year: 2017 ident: 10021_CR58 publication-title: Asian Pac J Cancer Prev doi: 10.22034/APJCP.2017.18.1.3 – volume: 9 start-page: 1 year: 2011 ident: 10021_CR104 publication-title: BMC Biol doi: 10.1186/1741-7007-9-71 – volume: 12 start-page: 383 year: 2012 ident: 10021_CR8 publication-title: Expert Rev Mol Diagn doi: 10.1586/erm.12.30 – volume: 2 start-page: 1 year: 2019 ident: 10021_CR194 publication-title: Cancer Rep doi: 10.1002/cnr2.1220 – volume: 17 start-page: 225 year: 2010 ident: 10021_CR40 publication-title: Cancer Cell doi: 10.1016/j.ccr.2010.01.020 – volume: 33 start-page: 852 year: 2012 ident: 10021_CR211 publication-title: Am J Neuroradiol doi: 10.3174/ajnr.A2895 – volume: 10 start-page: 240 year: 2010 ident: 10021_CR36 publication-title: Curr Neurol Neurosci Rep doi: 10.1007/s11910-010-0109-3 – volume: 8 start-page: CNS43 year: 2019 ident: 10021_CR81 publication-title: CNS Oncol doi: 10.2217/cns-2019-0014 – volume: 14 start-page: 958 year: 2012 ident: 10021_CR13 publication-title: Neuro Oncol doi: 10.1093/neuonc/nos116 – volume: 44 start-page: 235 year: 2000 ident: 10021_CR120 publication-title: J Pharmacol Toxicol Methods doi: 10.1016/S1056-8719(00)00107-6 – volume: 134 start-page: 505 year: 2017 ident: 10021_CR42 publication-title: J Neurooncol doi: 10.1007/s11060-017-2379-y – volume: 20 start-page: 1375 year: 2019 ident: 10021_CR110 publication-title: Int J Mol Sci doi: 10.3390/ijms20061375 – volume: 8 start-page: 235 year: 2018 ident: 10021_CR142 publication-title: Biomed Rep doi: 10.3892/br.2018.1051 – volume: 8 start-page: 1 year: 2018 ident: 10021_CR66 publication-title: Front Oncol doi: 10.3389/fonc.2018.00419 – volume: 8 start-page: 44015 year: 2017 ident: 10021_CR60 publication-title: Oncotarget doi: 10.18632/oncotarget.17054 – volume: 8 start-page: 44255 year: 2017 ident: 10021_CR144 publication-title: Oncotarget doi: 10.18632/oncotarget.17464 – volume: 112 start-page: 837 year: 2020 ident: 10021_CR192 publication-title: Genomics doi: 10.1016/j.ygeno.2019.05.024 – volume: 37 start-page: 61 year: 2016 ident: 10021_CR11 publication-title: Tumor Biol doi: 10.1007/s13277-015-4242-0 – volume: 96 start-page: 1047 year: 2007 ident: 10021_CR79 publication-title: Br J Cancer doi: 10.1038/sj.bjc.6603669 – volume: 9 start-page: 414 year: 2011 ident: 10021_CR167 publication-title: JNCCN J Natl Compr Cancer Netw doi: 10.6004/jnccn.2011.0038 – volume: 6 start-page: S85 year: 2015 ident: 10021_CR48 publication-title: Surg Neurol Int doi: 10.4103/2152-7806.151348 – volume: 20 start-page: 1 year: 2020 ident: 10021_CR1 publication-title: BMC Cancer doi: 10.1186/s12885-019-6511-6 – volume: 8 start-page: 4103 year: 2017 ident: 10021_CR19 publication-title: J Neurosci Rural Pract doi: 10.4103/jnrp.jnrp – volume: 110 start-page: 14912 year: 2013 ident: 10021_CR76 publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.1310894110 – volume: 20 start-page: 22799 year: 2015 ident: 10021_CR113 publication-title: Molecules doi: 10.3390/molecules201219880 – volume: 123 start-page: 325 year: 2015 ident: 10021_CR196 publication-title: J Neurosurg doi: 10.3171/2014.10.JNS141520 – volume: 9 start-page: 1 year: 2018 ident: 10021_CR197 publication-title: Front Neurol doi: 10.3389/fneur.2018.00033 – volume: 16 start-page: 861 year: 2019 ident: 10021_CR150 publication-title: Lett Drug Des Discov doi: 10.2174/1570180815666180808094432 – volume: 5 start-page: 1103 year: 2013 ident: 10021_CR45 publication-title: Cancers (Basel) doi: 10.3390/cancers5031103 – year: 2019 ident: 10021_CR95 publication-title: Front Oncol doi: 10.3389/fonc.2019.00417 – volume: 13 start-page: 582 year: 2006 ident: 10021_CR128 publication-title: Nat Struct Mol Biol doi: 10.1038/nsmb1105 – volume: 9 start-page: 646 year: 2002 ident: 10021_CR101 publication-title: Nat Struct Biol doi: 10.1038/nsb0902-646 – volume: 7 start-page: 1 year: 2020 ident: 10021_CR39 publication-title: Front Mol Biosci doi: 10.3389/fmolb.2020.562798 – volume: 35 start-page: 1 year: 2016 ident: 10021_CR49 publication-title: J Exp Clin Cancer Res doi: 10.1186/s13046-016-0362-7 – volume: 21 start-page: 65 year: 2018 ident: 10021_CR106 publication-title: TIP Rev Espec en Ciencias Quim Biol – volume: 9 start-page: 1 year: 2020 ident: 10021_CR29 publication-title: F1000Research doi: 10.12688/f1000research.22440.1 – volume: 16 start-page: 973 year: 2012 ident: 10021_CR72 publication-title: Expert Opin Ther Targets doi: 10.1517/14728222.2012.711817 – volume: 28 start-page: 2817 year: 2010 ident: 10021_CR90 publication-title: J Clin Oncol doi: 10.1200/JCO.2009.26.3988 – volume: 22 start-page: 6661 year: 2003 ident: 10021_CR174 publication-title: Oncogene doi: 10.1038/sj.onc.1206763 – volume: 10 start-page: e00570 year: 2020 ident: 10021_CR121 publication-title: Sci Afr doi: 10.1016/j.sciaf.2020.e00570 – volume: 114 start-page: 97 year: 2007 ident: 10021_CR7 publication-title: Acta Neuropathol doi: 10.1007/s00401-007-0243-4 – volume: 9 start-page: 1 year: 2019 ident: 10021_CR183 publication-title: Front Oncol doi: 10.3389/fonc.2019.00506 – volume: 38 start-page: 1 year: 2019 ident: 10021_CR85 publication-title: J Exp Clin Cancer Res doi: 10.1186/s13046-019-1264-2 – volume: 25 start-page: 1 year: 2020 ident: 10021_CR153 publication-title: Molecules doi: 10.3390/molecules25163633 – volume: 27 start-page: 196 year: 1984 ident: 10021_CR59 publication-title: J Med Chem doi: 10.1021/jm00368a016 – volume: 24 start-page: 180 year: 2018 ident: 10021_CR68 publication-title: Cancer J (United States) doi: 10.1097/ppo.0000000000000326 – year: 2012 ident: 10021_CR200 publication-title: Surg Neurol Int doi: 10.4103/2152-7806.103029 – volume: 5 start-page: 102 year: 2012 ident: 10021_CR55 publication-title: Curr Mol Pharmacol doi: 10.2174/1874-470211205010102 – volume: 15 start-page: 30 year: 2019 ident: 10021_CR25 publication-title: Eur Endocrinol doi: 10.17925/EE.2019.15.1.30 – ident: 10021_CR162 doi: 10.2174/1568009616666161227091522 – volume: 20 start-page: 22 year: 1957 ident: 10021_CR23 publication-title: J Neurol Neurosurg Psychiatry doi: 10.1136/jnnp.20.1.22 – volume: 76 start-page: 1 year: 2010 ident: 10021_CR131 publication-title: Chem Biol Drug Des doi: 10.1111/j.1747-0285.2010.00986.x – volume: 6 start-page: 96735 year: 2016 ident: 10021_CR147 publication-title: RSC Adv doi: 10.1039/c6ra21617j – volume: 119 start-page: 1781 year: 2012 ident: 10021_CR123 publication-title: Blood doi: 10.1182/blood-2011-11-390922 – year: 2015 ident: 10021_CR198 publication-title: Sci Transl Med doi: 10.1126/scitranslmed.3010611 – volume: 15 start-page: 15994 year: 2014 ident: 10021_CR88 publication-title: Int J Mol Sci doi: 10.3390/ijms150915994 – volume: 23 start-page: 1531 year: 2017 ident: 10021_CR37 publication-title: Contin Lifelong Learn Neurol doi: 10.1212/CON.0000000000000536 – volume: 277 start-page: 46265 year: 2002 ident: 10021_CR122 publication-title: J Biol Chem doi: 10.1074/jbc.M207135200 – volume-title: Current standards of care in glioblastoma therapy year: 2016 ident: 10021_CR61 doi: 10.1016/B978-0-323-47660-7.00006-9 – volume: 12 start-page: 769 year: 2017 ident: 10021_CR115 publication-title: Expert Opin Drug Discov – year: 2017 ident: 10021_CR32 publication-title: Surg Neurol Int doi: 10.4103/sni.sni_490_16 – volume: 19 start-page: 1325 year: 2019 ident: 10021_CR100 publication-title: Anticancer Agents Med Chem doi: 10.2174/1871520619666190405111526 – volume: 9 start-page: 1 year: 2020 ident: 10021_CR38 publication-title: Front Oncol doi: 10.3389/fonc.2019.01547 – volume: 481 start-page: 227 year: 2000 ident: 10021_CR14 publication-title: FEBS Lett doi: 10.1016/S0014-5793(00)02011-1 – volume: 269 start-page: 718 year: 2000 ident: 10021_CR46 publication-title: Biochem Biophys Res Commun doi: 10.1006/bbrc.2000.2339 – volume: 14 start-page: 1131 year: 2009 ident: 10021_CR67 publication-title: Oncologist doi: 10.1634/theoncologist.2009-0121 – volume: 37 start-page: 1 year: 2018 ident: 10021_CR86 publication-title: J Exp Clin Cancer Res doi: 10.1186/s13046-018-0785-4 – volume: 1 start-page: 1 year: 2011 ident: 10021_CR151 publication-title: J Clin Bioinform doi: 10.1186/2043-9113-1-5 – year: 2019 ident: 10021_CR22 publication-title: Cancer Epidemiol doi: 10.1016/j.canep.2019.07.001 – volume: 131 start-page: 803 year: 2016 ident: 10021_CR35 publication-title: Acta Neuropathol doi: 10.1007/s00401-016-1545-1 – volume: 8 start-page: 13 year: 2020 ident: 10021_CR10 publication-title: Oncol Ther doi: 10.1007/s40487-019-00108-x – volume: 12 start-page: 1 year: 2020 ident: 10021_CR171 publication-title: Cancers (Basel) doi: 10.3390/cancers12123825 – volume: 20 start-page: VII17 year: 2018 ident: 10021_CR41 publication-title: Neuro Oncol doi: 10.1093/neuonc/noy158 – start-page: 238 volume-title: Review: book reviews reviewed work (s): the common place of law stories from everyday life by Patricia year: 2016 ident: 10021_CR164 doi: 10.1128/MCB.25.17.7734 – volume: 29 start-page: 159 year: 2008 ident: 10021_CR26 publication-title: Am J Neuroradiol doi: 10.3174/ajnr.A0750 – volume: 28 start-page: 388 year: 2018 ident: 10021_CR146 publication-title: Bioorg Med Chem Lett doi: 10.1016/j.bmcl.2017.12.030 – volume: 192 start-page: 539 year: 2015 ident: 10021_CR126 publication-title: J Struct Biol doi: 10.1016/j.jsb.2015.10.018 – volume: 4 start-page: 35 year: 2016 ident: 10021_CR30 publication-title: Oncol Ther doi: 10.1007/s40487-016-0016-0 – volume: 75 start-page: 20 year: 2020 ident: 10021_CR189 publication-title: Clin Radiol doi: 10.1016/j.crad.2019.07.001 – volume: 41 start-page: 1723 year: 2016 ident: 10021_CR20 publication-title: Neurochem Res doi: 10.1007/s11064-016-1888-y – volume: 117 start-page: 379 year: 2014 ident: 10021_CR24 publication-title: J Neurooncol doi: 10.1007/s11060-013-1354-5 – volume: 25 start-page: 7734 year: 2005 ident: 10021_CR165 publication-title: Mol Cell Biol doi: 10.1128/mcb.25.17.7734-7742.2005 – volume: 13 start-page: 701 year: 2009 ident: 10021_CR71 publication-title: Expert Opin Ther Targets doi: 10.1517/14728220902942348 – volume: 9 start-page: 347 year: 2010 ident: 10021_CR201 publication-title: Technol Cancer Res Treat doi: 10.1177/153303461000900405 – year: 2016 ident: 10021_CR195 publication-title: Biomed Res Int doi: 10.1155/2016/9734512 – volume: 18 start-page: 16 year: 2016 ident: 10021_CR186 publication-title: Neuro Oncol doi: 10.1093/neuonc/nov136 – volume: 2 start-page: 1 year: 2019 ident: 10021_CR190 publication-title: Cancer Rep doi: 10.1002/cnr2.1226 – volume: 6 start-page: 48 year: 2009 ident: 10021_CR56 publication-title: Chem World – volume: 15 start-page: 4041 year: 2010 ident: 10021_CR163 publication-title: Molecules doi: 10.3390/molecules15064041 – volume: 7 start-page: 81 year: 2014 ident: 10021_CR111 publication-title: J Receptor Ligand Channel Res doi: 10.2147/JRLCR.S46843 – volume: 8 start-page: 16052 year: 2017 ident: 10021_CR169 publication-title: Oncotarget doi: 10.18632/oncotarget.14109 – volume: 16 start-page: 565 year: 2012 ident: 10021_CR179 publication-title: Cell Metab doi: 10.1016/j.cmet.2012.09.013 – ident: 10021_CR210 – volume: 82 start-page: 638 year: 2004 ident: 10021_CR21 publication-title: J Mol Med doi: 10.1007/s00109-004-0565-9 – volume-title: Computer-aided prediction of pharmacokinetic (ADMET) properties year: 2018 ident: 10021_CR119 doi: 10.1016/B978-0-12-814421-3.00021-X – volume: 58 start-page: 405 year: 2018 ident: 10021_CR62 publication-title: Neurol Med Chir (Tokyo) doi: 10.2176/nmc.ra.2018-0141 – year: 2019 ident: 10021_CR98 publication-title: Silico Drug Des doi: 10.1016/b978-0-12-816125-8.00002-x – volume: 3 start-page: 95 year: 2015 ident: 10021_CR33 publication-title: Ann Transl Med doi: 10.3978/j.issn.2305-5839.2015.03.57 – volume: 15 start-page: 1473 year: 2020 ident: 10021_CR116 publication-title: Expert Opin Drug Discov doi: 10.1080/17460441.2020.1798926 – volume: 22 start-page: 195 year: 2006 ident: 10021_CR117 publication-title: Bioinformatics doi: 10.1093/bioinformatics/bti770 – volume: 60 start-page: 4109 year: 2020 ident: 10021_CR109 publication-title: J Chem Inf Model doi: 10.1021/acs.jcim.0c01009 – volume: 5 start-page: 18662 year: 2020 ident: 10021_CR135 publication-title: ACS Omega doi: 10.1021/acsomega.0c01323 – volume: 7 start-page: 1 year: 2017 ident: 10021_CR43 publication-title: Front Oncol doi: 10.3389/fonc.2017.00236 – volume: 7 start-page: 1 year: 2017 ident: 10021_CR124 publication-title: Sci Rep doi: 10.1038/s41598-017-05931-8 – volume: 20 start-page: 2839 year: 2013 ident: 10021_CR108 publication-title: Curr Med Chem doi: 10.2174/09298673113209990001 – volume: 10 start-page: 1663 year: 2019 ident: 10021_CR177 publication-title: J Cancer doi: 10.7150/jca.28231 – volume: 5 start-page: 1 year: 2019 ident: 10021_CR205 publication-title: Chinese Neurosurg J doi: 10.1186/s41016-019-0159-6 – volume: 21 start-page: 1 year: 2020 ident: 10021_CR50 publication-title: Int J Mol Sci doi: 10.3390/ijms21061932 – volume: 7 start-page: 833 year: 2006 ident: 10021_CR172 publication-title: Nat Rev Mol Cell Biol doi: 10.1038/nrm2039 – volume: 60 start-page: 2635 year: 2019 ident: 10021_CR181 publication-title: Leuk Lymphoma doi: 10.1080/10428194.2019.1602260 – volume: 12 start-page: 727 year: 2017 ident: 10021_CR65 publication-title: Asian J Neurosurg doi: 10.4103/ajns.ajns_39_15 – year: 2013 ident: 10021_CR168 publication-title: Sci World J doi: 10.1155/2013/417413 – year: 2013 ident: 10021_CR12 publication-title: Clin Dev Immunol doi: 10.1155/2013/285246 – year: 2016 ident: 10021_CR93 publication-title: Biomed Res Int doi: 10.1155/2016/1450843 – volume: 20 start-page: 300211 year: 2020 ident: 10021_CR75 publication-title: Oncol Lett doi: 10.3892/ol.2020.11927 – volume: 36 start-page: 3499 year: 2015 ident: 10021_CR140 publication-title: Tumor Biol doi: 10.1007/s13277-014-2986-6 – volume: 39 start-page: 415 year: 2019 ident: 10021_CR138 publication-title: J Recept Signal Transduct doi: 10.1080/10799893.2019.1690509 – volume: 28 start-page: 34 year: 2020 ident: 10021_CR130 publication-title: Asia-Pac J Mol Biol Biotechnol doi: 10.35118/apjmbb.2020.028.1.04 – volume: 7 start-page: 1 year: 2017 ident: 10021_CR166 publication-title: Front Oncol doi: 10.3389/fonc.2017.00182 – volume: 20 start-page: 432 year: 2018 ident: 10021_CR83 publication-title: Neoplasia (United States) doi: 10.1016/j.neo.2018.02.004 – volume: 121 start-page: 91 year: 2015 ident: 10021_CR89 publication-title: J Neurooncol doi: 10.1007/s11060-014-1612-1 – volume: 79 start-page: 604 year: 2016 ident: 10021_CR199 publication-title: Neurosurgery doi: 10.1227/NEU.0000000000001365 – volume: 15 start-page: 468 year: 2005 ident: 10021_CR213 publication-title: Eur Radiol doi: 10.1007/s00330-004-2555-2 – volume: 68 start-page: 59 year: 2021 ident: 10021_CR99 publication-title: Semin Cancer Biol doi: 10.1016/j.semcancer.2019.09.023 – volume: 11 start-page: 101 year: 2020 ident: 10021_CR77 publication-title: ACS Med Chem Lett doi: 10.1021/acsmedchemlett.9b00509 – volume: 16 start-page: 1431 year: 2018 ident: 10021_CR143 publication-title: Oncol Lett doi: 10.3892/ol.2018.8873 – volume: 40 start-page: 1299 year: 2019 ident: 10021_CR184 publication-title: Carcinogenesis doi: 10.1093/carcin/bgz134 – volume: 18 start-page: 170 year: 2021 ident: 10021_CR4 publication-title: Nat Rev Clin Oncol doi: 10.1038/s41571-020-00447-z – volume: 3 start-page: 1 issue: NOV year: 2013 ident: 10021_CR207 publication-title: Front Oncol doi: 10.3389/fonc.2013.00284 – volume: 11 start-page: 1 year: 2020 ident: 10021_CR145 publication-title: Front Pharmacol doi: 10.3389/fphar.2020.579768 – volume: 10 start-page: 2589 year: 2015 ident: 10021_CR180 publication-title: ACS Chem Biol doi: 10.1021/acschembio.5b00466 – volume: 26 start-page: 67 year: 2000 ident: 10021_CR44 publication-title: Cancer Treat Rev doi: 10.1053/ctrv.1999.0145 – volume: 119 start-page: 157 year: 2010 ident: 10021_CR74 publication-title: Acta Neuropathol doi: 10.1007/s00401-009-0614-0 – volume: 9 start-page: 1 year: 2018 ident: 10021_CR206 publication-title: Front Pharmacol doi: 10.3389/fphar.2018.00879 – volume: 63 start-page: 1612 year: 2020 ident: 10021_CR149 publication-title: J Med Chem doi: 10.1021/acs.jmedchem.9b01423 – volume: 8 start-page: 37 year: 2015 ident: 10021_CR103 publication-title: Adv Appl Bioinform Chem – volume: 14 start-page: 683 year: 2001 ident: 10021_CR6 publication-title: Curr Opin Neurol doi: 10.1097/00019052-200112000-00002 – year: 2015 ident: 10021_CR9 publication-title: Nat Rev Dis Prim doi: 10.1038/nrdp.2015.17 – volume: 30 start-page: 21 year: 2019 ident: 10021_CR91 publication-title: Neuro Oncol doi: 10.1093/neuonc/noz126.072 – volume: 21 start-page: 2787 year: 2003 ident: 10021_CR80 publication-title: J Clin Oncol doi: 10.1200/JCO.2003.01.504 – volume: 102 start-page: 932 year: 2010 ident: 10021_CR182 publication-title: J Natl Cancer Inst doi: 10.1093/jnci/djq187 – volume: 15 start-page: 1 year: 2015 ident: 10021_CR209 publication-title: BMC Cancer doi: 10.1186/s12885-015-1810-z – volume: 3 start-page: 37 year: 2014 ident: 10021_CR3 publication-title: CNS Oncol doi: 10.2217/cns.13.65 – volume: 26 start-page: 551 year: 2019 ident: 10021_CR63 publication-title: Drug Deliv doi: 10.1080/10717544.2019.1616235 – volume: 9 start-page: 703 year: 2012 ident: 10021_CR157 publication-title: Anticancer Agents Med Chem doi: 10.2174/187152009788680019 – volume: 15 start-page: 3219 year: 2014 ident: 10021_CR34 publication-title: Asian Pac J Cancer Prev doi: 10.7314/APJCP.2014.15.7.3219 |
| SSID | ssj0028972 ssj0009880 |
| Score | 2.3800673 |
| SecondaryResourceType | review_article |
| Snippet | Amongst the several types of brain cancers known to humankind, glioma is one of the most severe and life-threatening types of cancer, comprising 40% of all... |
| SourceID | proquest gale pubmed crossref springer |
| SourceType | Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 601 |
| SubjectTerms | Animal Anatomy Antineoplastic Agents - chemistry Antineoplastic Agents - therapeutic use Biochemistry Bioorganic Chemistry Brain Brain cancer Brain Neoplasms - drug therapy Brain Neoplasms - genetics Brain Neoplasms - metabolism Brain tumors CAD Cancer Chemical compounds Chemistry Chemistry and Materials Science Chemotherapy Computational neuroscience Computer aided design Design Drug Design Drug development Drug Discovery Drug therapy Glioma Glioma - drug therapy Glioma - genetics Glioma - metabolism Health aspects Histology Humans Morphology Organic Chemistry Patients Pharmacology Survival Temozolomide Therapeutic targets |
| SummonAdditionalLinks | – databaseName: Springer Journals dbid: RSV link: http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnR1dTxQxcIJgIi-ioLCAZkmMPmiT3W232_J24QSfCJHT8NZsv8wlsEfuQ-K_d9rbveOImsjDvmxnmnZ2pjOznQ-Ad8ZJbqkviTc2I8xoTrQoSxLeeyu1qTIdm01U5-fi6kpetElhky7avbuSjCf1vWQ3STMSQgryGFhw9wQ2UN2J0LDh6-X3ZandyJKtzyVk7N-Ul1VBKApUmzfz5wlXdNPDE_qeinpwZxpV0enW4zbxAp63pmfam_PKS1hzzTbs9Bp0u29-pe_TGAwa_7Jvw7OTrhHcDvTProejm5oMYtC4s-lgmbM1OU67vhCkN7Q42B_PfqT9GBeSXoxHXSbnK_h2-nlw8oW0zReIYayYktwztBWowUdrR7kVLNdFbmtpHNpEhlLmrRbeZVz6QtRot1Xc1dwhHvpgmr6G9WbUuD1IfW1lXUpEQeFHC06iScNpLXxhmBdCJ5B3ZFemrUweGmRcq2VN5UA2hQRTkWzqLoGPC5zbeV2Of0J_CF9TBaHFmU3d5h7g-kL5K9XDFZdFVUqawOEKJJLarA53_KBaYZ8oPPWk4FwKHD5aDAfMEMDWuNEswog8enMJ7M75aLFuykICsGQJfOqYZjn53ze1_3_gB7BZzPmOZPkhrE_HM_cGnpqf0-Fk_DaK0G-26BFI priority: 102 providerName: Springer Nature |
| Title | Glioma-Targeted Therapeutics: Computer-Aided Drug Design Prospective |
| URI | https://link.springer.com/article/10.1007/s10930-021-10021-w https://www.ncbi.nlm.nih.gov/pubmed/34590194 https://www.proquest.com/docview/2579866983 https://www.proquest.com/docview/2578151182 |
| Volume | 40 |
| WOSCitedRecordID | wos000701350800001&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| journalDatabaseRights | – providerCode: PRVAVX databaseName: Springer Journals customDbUrl: eissn: 1573-4943 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0028972 issn: 1572-3887 databaseCode: RSV dateStart: 20040101 isFulltext: true titleUrlDefault: https://link.springer.com/search?facet-content-type=%22Journal%22 providerName: Springer Nature |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpR3ZbtQwcERbJPrC0XIEyipICB7AkMQ5bF7QttuChFityoL2LYqvaqU2KXtQ8feMvc6GrURfeIilxIfGmfF4xp4D4KXUPFfUZMRIFZFUipwIlmXEfjeKC1lEwiWbKIZDNpnwkT9wm3uzypYnOkatGmnPyN8jaXGW55zRj5c_ic0aZW9XfQqNLdhBySa2Jl1fk1EXdNcRp9e-GHeZnOKsSAjFpeU9aLwfHacRsdYKsbNZuNrYpa7z6r82q2u3p25TOrn3v9O5D3e9OBr2V_TzAG7peg_2-zWq4he_w1ehMxB1J-97cOeoTQ63D4NP59PmoiJjZ0iuVTju_LjmH8I2VwTpTxVWDmbLs3DgbEXC0axpvTsfwveT4_HRZ-ITMhCZpsmCxCZF-YFKfITQNFcsjUUSq4pLjXKSpDQ1SjCjo5ybhFUoyxW5rnKN_VAvE_QRbNdNrZ9AaCrFq4xjF2QIKNVxFHNyWjGTyNQwJgKIWwSU0kcrt0kzzssuzrJFWonoKh3SyqsA3qz7XK5iddzY-rXFa2kXMo4sK--PgPDZkFhlHyHOkiLjNICDjZb4q-VmdYvi0jOAednhN4AX62rb0xq11bpZujYsdhpeAI9XFLWGm6bWKZinAbxtSawb_N-TenozLM9gN1lROYniA9hezJb6OdyWvxbT-awHW8WkcCXrwc7h8XB0im9fDt_13LKyZWHL028__gDLFyFQ |
| linkProvider | ProQuest |
| linkToHtml | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMw1V1Jb9QwFH4qBam9sLRQAgWCxHIoFomdxUZCaNShtGoZzWGQeguxY6OR2qTMwqh_it_Is5NMmEr01gOHXOJFz873FsdvAXiltEgKZmJiVBGQSMmESB7HxL43hZAqDaQrNpEOBvz0VAzX4HcbC2PdKluZ6AR1USn7j_w9QkvwJBGcfbr4SWzVKHu72pbQqGFxrC8XeGSbfjzq4_d9TenB59H-IWmqChAVRXRGQhOhEmQKHyk1SwoehZKGRS6URmWvGItMIbnRQSIM5TkaJGmi80TjODxcSIbz3oLbkc0sZl0F6bBL8uuYoTntceEqR4VxSglDVm4idpq4PcECYr0jQucjsVjRild1w1_K8cptrVOCB_f-t-27D3cbc9vv1fzxANZ0uQXbvTKfVeeX_hvfOcC6m4Ut2Nhvi99tQ__L2bg6z8nIOcrrwh91cWrTD35bC4P0xgU29ifzH37f-cL4w0nVRq8-hG83srZHsF5WpX4MvskLkccCh6DAQ6tVoBmXsJwbqiLDufQgbD94ppps7LYoyFnW5ZG2IMkQHpkDSbbwYG855qLORXJt77cWR5kVVDizypt4C6TPpvzKekhxTNNYMA92V3riVqvV5hZSWSPgplmHJw9eLpvtSOu0V-pq7vrw0J1gPdipEbykm0U26FlEHrxrId1N_u9FPbmelhewcTj6epKdHA2On8ImrTmMBOEurM8mc_0M7qhfs_F08twxrg_fbxrqfwDu2Xdh |
| linkToPdf | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMw1V1Jb9QwFH4qUwRcWFqWQIEgsRzAahJnsZEQGpoOVEWjEZpKvYXYsdFIbVJmYdS_xq_j2UkmTCV664FDLvEi2_neFr8F4KVUPC6ojoiWhUdCKWIiWBQR814XXMjEE7bYRDIcsuNjPtqA320sjHGrbHmiZdRFJc0_8l2EFmdxzBnd1Y1bxCgdfDz7SUwFKXPT2pbTqCFyqM6XaL7NPhyk-K1fBcFgf7z3hTQVBogMw2BOfB2iQKQSHyEUjQsW-iLwi5xLhYJfUhrqQjCtvJjrgOWonCSxymOF49DQEBTnvQabCSoZYQ82P-0PR9-6lL-WNBrbj3FbR8qPkoBQJOwmfqeJ4uPUI8ZXwrceE8s1GXlRUvwlKi_c3VqROLjzPx_mXbjdKOJuv6ace7Chyi3Y7pf5vDo9d1-71jXW3jlswc29tizeNqSfTybVaU7G1oVeFe64i2CbvXfbKhmkPymwMZ0ufrip9ZJxR9OqjWu9D0dXsrcH0CurUj0CV-cFzyOOQ5AVoj7LUcGLac50IEPNmHDAbz9-Jps87aZcyEnWZZg2gMkQKpkFTLZ04O1qzFmdpeTS3m8MpjLDwnBmmTeRGLg-kwws6-OKoyCJOHVgZ60nHrVcb27hlTWsb5Z12HLgxarZjDTufKWqFrYP861t68DDGs2rddPQhEPz0IF3Lby7yf-9qceXr-U53ECEZ18PhodP4FZQExvx_B3ozacL9RSuy1_zyWz6rKFiF75fNdb_APnFgXs |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Glioma-Targeted+Therapeutics%3A+Computer-Aided+Drug+Design+Prospective&rft.jtitle=The+protein+journal&rft.au=Poonan%2C+Preantha&rft.au=Agoni%2C+Clement&rft.au=Ibrahim%2C+Mahmoud+A.+A.&rft.au=Soliman%2C+Mahmoud+E.+S.&rft.date=2021-10-01&rft.issn=1572-3887&rft.eissn=1875-8355&rft.volume=40&rft.issue=5&rft.spage=601&rft.epage=655&rft_id=info:doi/10.1007%2Fs10930-021-10021-w&rft.externalDBID=n%2Fa&rft.externalDocID=10_1007_s10930_021_10021_w |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1572-3887&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1572-3887&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1572-3887&client=summon |