Histone Deacetylases and Histone Deacetylase Inhibitors in Neuroblastoma

Histone deacetylases (HDACs) are enzymes that play a key role in regulating gene expression by remodeling chromatin structure. An imbalance of histone acetylation caused by deregulated HDAC expression and activity is known to promote tumor progression in a number of tumor types, including neuroblast...

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Bibliographic Details
Published in:Frontiers in cell and developmental biology Vol. 8; p. 578770
Main Authors: Phimmachanh, Monica, Han, Jeremy Z. R., O’Donnell, Yolande E. I., Latham, Sharissa L., Croucher, David R.
Format: Journal Article
Language:English
Published: Frontiers Media S.A 07.10.2020
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ISSN:2296-634X, 2296-634X
Online Access:Get full text
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