The tumor microenvironment as driver of stemness and therapeutic resistance in breast cancer: New challenges and therapeutic opportunities

Background Breast cancer (BC), the second most common cause of cancer-related deaths, remains a significant threat to the health and wellness of women worldwide. The tumor microenvironment (TME), comprising cellular components, such as cancer-associated fibroblasts (CAFs), immune cells, endothelial...

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Bibliographic Details
Published in:	Cellular oncology (Dordrecht) Vol. 44; no. 6; pp. 1209 - 1229
Main Authors:	Mehraj, Umar, Ganai, Rais A., Macha, Muzafar A., Hamid, Abid, Zargar, Mohammed A., Bhat, Ajaz A., Nasser, Mohd Wasim, Haris, Mohammad, Batra, Surinder K., Alshehri, Bader, Al-Baradie, Raid Saleem, Mir, Manzoor A., Wani, Nissar Ahmad
Format:	Journal Article
Language:	English
Published:	Dordrecht Springer Netherlands 01.12.2021 Springer Nature B.V
Subjects:	Adipocytes Animals Biomedical and Life Sciences Biomedicine Breast cancer Breast Neoplasms - drug therapy Breast Neoplasms - pathology Cancer Research Cancer-Associated Fibroblasts - pathology Clinical trials Dormancy Drug Resistance, Neoplasm Endothelial cells Extracellular matrix Female Fibroblasts Humans Metastases Metastasis Molecular Targeted Therapy Neoplastic Stem Cells - pathology Oncology Pathology Phenotypic plasticity Radiation therapy Review Tumor Microenvironment Tumors Cancer-associated fibroblasts Tumor microenvironment Immunotherapy Targeted therapeutics Cancer stemness Breast cancer Tumor-associated macrophages
ISSN:	2211-3428, 2211-3436, 2211-3436
Online Access:	Get full text
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