Validation of central serous chorioretinopathy multimodal imaging-based classification system
Purpose Validation of a recently described central serous chorioretinopathy (CSCR) classification system and assessment of levels of agreement among 10 retina physicians. Methods This was a cross-sectional (inter-reader agreement) study. Ten retina physicians (assigned a role of masked grader) were...
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| Veröffentlicht in: | Graefe's archive for clinical and experimental ophthalmology Jg. 260; H. 4; S. 1161 - 1169 |
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| Format: | Journal Article |
| Sprache: | Englisch |
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Springer Berlin Heidelberg
01.04.2022
Springer Nature B.V |
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| ISSN: | 0721-832X, 1435-702X, 1435-702X |
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| Abstract | Purpose
Validation of a recently described central serous chorioretinopathy (CSCR) classification system and assessment of levels of agreement among 10 retina physicians.
Methods
This was a cross-sectional (inter-reader agreement) study. Ten retina physicians (assigned a role of masked grader) were provided with a comprehensive dataset of 61 eyes of 34 patients of presumed CSCR. Relevant clinical details and multimodal imaging (fundus autofluorescence, fluorescein and indocyanine green angiography, optical coherence tomography) of both involved and fellow eye were electronically shared. Later, only the fellow eye images were resent to understand the influence of affected eye on the grading of the fellow eye. Multiple inter-grader agreement using Fleiss Kappa was performed to determine the level of agreement among the 10 graders.
p
value of ≤ 0.05 was considered statistically significant.
Results
Sixty-one eyes of 34 patients were evaluated. There was moderate agreement for major criteria with Fleiss Kappa value of 0.50 (
p
< 0.0001) with a single outlier observer. After excluding that observer, the Fleiss Kappa value increased to 0.57 (
p
< 0.0001) with statistically significant
p
values among all categories, i.e., simple CSC (
κ
= 0.575), complex CSC (
κ
= 0.621), and no CSC (
κ
= 0.452). Overall, moderate to substantial agreement was noted among the subtypes (primary, recurrent, and resolved). The influence of the affected eye on fellow eye grading was studied. The global Fleiss Kappa coefficient (
κ
= 0.642,
p
< 0.0001) showed substantial agreement when observers were aware of the affected eye grading. However, without prior available information on the affected eye, the inter-grader agreement was significantly lower (global
κ
= 0.255,
p
< 0.0001).
Conclusion
A fair-moderate inter-grader agreement among the masked graders suggests a need for further refinement of this novel classification system. Disease grading should include both eyes as lack of information on affected eye has a bearing on fellow eye grading and inter-grader agreement as shown by a significant difference in global
κ
values. |
|---|---|
| AbstractList | Validation of a recently described central serous chorioretinopathy (CSCR) classification system and assessment of levels of agreement among 10 retina physicians.
This was a cross-sectional (inter-reader agreement) study. Ten retina physicians (assigned a role of masked grader) were provided with a comprehensive dataset of 61 eyes of 34 patients of presumed CSCR. Relevant clinical details and multimodal imaging (fundus autofluorescence, fluorescein and indocyanine green angiography, optical coherence tomography) of both involved and fellow eye were electronically shared. Later, only the fellow eye images were resent to understand the influence of affected eye on the grading of the fellow eye. Multiple inter-grader agreement using Fleiss Kappa was performed to determine the level of agreement among the 10 graders. p value of ≤ 0.05 was considered statistically significant.
Sixty-one eyes of 34 patients were evaluated. There was moderate agreement for major criteria with Fleiss Kappa value of 0.50 (p < 0.0001) with a single outlier observer. After excluding that observer, the Fleiss Kappa value increased to 0.57 (p < 0.0001) with statistically significant p values among all categories, i.e., simple CSC ([Formula: see text] = 0.575), complex CSC ([Formula: see text] = 0.621), and no CSC ([Formula: see text] = 0.452). Overall, moderate to substantial agreement was noted among the subtypes (primary, recurrent, and resolved). The influence of the affected eye on fellow eye grading was studied. The global Fleiss Kappa coefficient ([Formula: see text] = 0.642, p < 0.0001) showed substantial agreement when observers were aware of the affected eye grading. However, without prior available information on the affected eye, the inter-grader agreement was significantly lower (global [Formula: see text] = 0.255, p < 0.0001).
A fair-moderate inter-grader agreement among the masked graders suggests a need for further refinement of this novel classification system. Disease grading should include both eyes as lack of information on affected eye has a bearing on fellow eye grading and inter-grader agreement as shown by a significant difference in global [Formula: see text] values. Validation of a recently described central serous chorioretinopathy (CSCR) classification system and assessment of levels of agreement among 10 retina physicians.PURPOSEValidation of a recently described central serous chorioretinopathy (CSCR) classification system and assessment of levels of agreement among 10 retina physicians.This was a cross-sectional (inter-reader agreement) study. Ten retina physicians (assigned a role of masked grader) were provided with a comprehensive dataset of 61 eyes of 34 patients of presumed CSCR. Relevant clinical details and multimodal imaging (fundus autofluorescence, fluorescein and indocyanine green angiography, optical coherence tomography) of both involved and fellow eye were electronically shared. Later, only the fellow eye images were resent to understand the influence of affected eye on the grading of the fellow eye. Multiple inter-grader agreement using Fleiss Kappa was performed to determine the level of agreement among the 10 graders. p value of ≤ 0.05 was considered statistically significant.METHODSThis was a cross-sectional (inter-reader agreement) study. Ten retina physicians (assigned a role of masked grader) were provided with a comprehensive dataset of 61 eyes of 34 patients of presumed CSCR. Relevant clinical details and multimodal imaging (fundus autofluorescence, fluorescein and indocyanine green angiography, optical coherence tomography) of both involved and fellow eye were electronically shared. Later, only the fellow eye images were resent to understand the influence of affected eye on the grading of the fellow eye. Multiple inter-grader agreement using Fleiss Kappa was performed to determine the level of agreement among the 10 graders. p value of ≤ 0.05 was considered statistically significant.Sixty-one eyes of 34 patients were evaluated. There was moderate agreement for major criteria with Fleiss Kappa value of 0.50 (p < 0.0001) with a single outlier observer. After excluding that observer, the Fleiss Kappa value increased to 0.57 (p < 0.0001) with statistically significant p values among all categories, i.e., simple CSC ([Formula: see text] = 0.575), complex CSC ([Formula: see text] = 0.621), and no CSC ([Formula: see text] = 0.452). Overall, moderate to substantial agreement was noted among the subtypes (primary, recurrent, and resolved). The influence of the affected eye on fellow eye grading was studied. The global Fleiss Kappa coefficient ([Formula: see text] = 0.642, p < 0.0001) showed substantial agreement when observers were aware of the affected eye grading. However, without prior available information on the affected eye, the inter-grader agreement was significantly lower (global [Formula: see text] = 0.255, p < 0.0001).RESULTSSixty-one eyes of 34 patients were evaluated. There was moderate agreement for major criteria with Fleiss Kappa value of 0.50 (p < 0.0001) with a single outlier observer. After excluding that observer, the Fleiss Kappa value increased to 0.57 (p < 0.0001) with statistically significant p values among all categories, i.e., simple CSC ([Formula: see text] = 0.575), complex CSC ([Formula: see text] = 0.621), and no CSC ([Formula: see text] = 0.452). Overall, moderate to substantial agreement was noted among the subtypes (primary, recurrent, and resolved). The influence of the affected eye on fellow eye grading was studied. The global Fleiss Kappa coefficient ([Formula: see text] = 0.642, p < 0.0001) showed substantial agreement when observers were aware of the affected eye grading. However, without prior available information on the affected eye, the inter-grader agreement was significantly lower (global [Formula: see text] = 0.255, p < 0.0001).A fair-moderate inter-grader agreement among the masked graders suggests a need for further refinement of this novel classification system. Disease grading should include both eyes as lack of information on affected eye has a bearing on fellow eye grading and inter-grader agreement as shown by a significant difference in global [Formula: see text] values.CONCLUSIONA fair-moderate inter-grader agreement among the masked graders suggests a need for further refinement of this novel classification system. Disease grading should include both eyes as lack of information on affected eye has a bearing on fellow eye grading and inter-grader agreement as shown by a significant difference in global [Formula: see text] values. PurposeValidation of a recently described central serous chorioretinopathy (CSCR) classification system and assessment of levels of agreement among 10 retina physicians.MethodsThis was a cross-sectional (inter-reader agreement) study. Ten retina physicians (assigned a role of masked grader) were provided with a comprehensive dataset of 61 eyes of 34 patients of presumed CSCR. Relevant clinical details and multimodal imaging (fundus autofluorescence, fluorescein and indocyanine green angiography, optical coherence tomography) of both involved and fellow eye were electronically shared. Later, only the fellow eye images were resent to understand the influence of affected eye on the grading of the fellow eye. Multiple inter-grader agreement using Fleiss Kappa was performed to determine the level of agreement among the 10 graders. p value of ≤ 0.05 was considered statistically significant.ResultsSixty-one eyes of 34 patients were evaluated. There was moderate agreement for major criteria with Fleiss Kappa value of 0.50 (p < 0.0001) with a single outlier observer. After excluding that observer, the Fleiss Kappa value increased to 0.57 (p < 0.0001) with statistically significant p values among all categories, i.e., simple CSC (κ = 0.575), complex CSC (κ = 0.621), and no CSC (κ = 0.452). Overall, moderate to substantial agreement was noted among the subtypes (primary, recurrent, and resolved). The influence of the affected eye on fellow eye grading was studied. The global Fleiss Kappa coefficient (κ = 0.642, p < 0.0001) showed substantial agreement when observers were aware of the affected eye grading. However, without prior available information on the affected eye, the inter-grader agreement was significantly lower (global κ = 0.255, p < 0.0001).ConclusionA fair-moderate inter-grader agreement among the masked graders suggests a need for further refinement of this novel classification system. Disease grading should include both eyes as lack of information on affected eye has a bearing on fellow eye grading and inter-grader agreement as shown by a significant difference in global κ values. Purpose Validation of a recently described central serous chorioretinopathy (CSCR) classification system and assessment of levels of agreement among 10 retina physicians. Methods This was a cross-sectional (inter-reader agreement) study. Ten retina physicians (assigned a role of masked grader) were provided with a comprehensive dataset of 61 eyes of 34 patients of presumed CSCR. Relevant clinical details and multimodal imaging (fundus autofluorescence, fluorescein and indocyanine green angiography, optical coherence tomography) of both involved and fellow eye were electronically shared. Later, only the fellow eye images were resent to understand the influence of affected eye on the grading of the fellow eye. Multiple inter-grader agreement using Fleiss Kappa was performed to determine the level of agreement among the 10 graders. p value of ≤ 0.05 was considered statistically significant. Results Sixty-one eyes of 34 patients were evaluated. There was moderate agreement for major criteria with Fleiss Kappa value of 0.50 ( p < 0.0001) with a single outlier observer. After excluding that observer, the Fleiss Kappa value increased to 0.57 ( p < 0.0001) with statistically significant p values among all categories, i.e., simple CSC ( κ = 0.575), complex CSC ( κ = 0.621), and no CSC ( κ = 0.452). Overall, moderate to substantial agreement was noted among the subtypes (primary, recurrent, and resolved). The influence of the affected eye on fellow eye grading was studied. The global Fleiss Kappa coefficient ( κ = 0.642, p < 0.0001) showed substantial agreement when observers were aware of the affected eye grading. However, without prior available information on the affected eye, the inter-grader agreement was significantly lower (global κ = 0.255, p < 0.0001). Conclusion A fair-moderate inter-grader agreement among the masked graders suggests a need for further refinement of this novel classification system. Disease grading should include both eyes as lack of information on affected eye has a bearing on fellow eye grading and inter-grader agreement as shown by a significant difference in global κ values. |
| Author | Behar-Cohen, Francine Chhablani, Jay |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/34669028$$D View this record in MEDLINE/PubMed |
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| CitedBy_id | crossref_primary_10_1111_ceo_14201 crossref_primary_10_1111_aos_16779 crossref_primary_10_1111_aos_16679 crossref_primary_10_1021_acs_jproteome_4c00561 crossref_primary_10_1016_j_pdpdt_2023_103896 crossref_primary_10_1038_s41433_023_02812_5 crossref_primary_10_1007_s00401_023_02628_3 crossref_primary_10_1007_s00417_024_06691_8 crossref_primary_10_1038_s41598_023_41126_0 crossref_primary_10_3390_jcm14051458 crossref_primary_10_1038_s41433_024_03253_4 crossref_primary_10_1097_IAE_0000000000003692 crossref_primary_10_1097_IAE_0000000000003845 crossref_primary_10_1186_s40942_023_00443_2 crossref_primary_10_1016_j_ajo_2024_01_025 crossref_primary_10_1016_j_preteyeres_2024_101236 crossref_primary_10_1097_APO_0000000000000584 crossref_primary_10_1111_aos_15263 crossref_primary_10_1007_s00347_025_02187_w |
| Cites_doi | 10.1037/h0031619 10.1016/j.oret.2020.07.026 10.1016/j.preteyeres.2021.100955 10.1177/11206721211013651 10.1016/j.ophtha.2016.03.017 10.1016/j.ajo.2021.05.029 10.1016/j.preteyeres.2019.07.003 10.1136/bjophthalmol-2018-312435 10.1016/j.ajo.2017.10.028 10.1038/s41433-021-01490-5 10.1016/j.preteyeres.2015.05.003 10.1016/j.ophtha.2018.12.048 10.1016/j.survophthal.2012.07.004 |
| ContentType | Journal Article |
| Contributor | Yzer, Suzanne Chhablani, Jay Bousquet, Elodie Freund, K Bailey Lotery, Andrew Sivaprasad, Sobha Mrejen, Sarah Aymard, Pauline Querques, Giuseppe Gaudric, Alain Beydoun, Talal Mantel, Irmela Lupidi, Marco Singh, Sumit Randhir Zweifel, Sandrine van Dijk, Elon H C Mathis, Thibaud Ruiz-Medrano, Jorge Zhao, Min Mauget-Faÿsse, Martine Mehanna, Chadi Daruich, Alejandra Ruiz-Moreno, Jose-Maria Boon, Camiel J F Spaide, Richard F Cheung, Chui Ming Gemmy Shulman, Shiri Behar-Cohen, Francine Matet, Alexandre |
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| Copyright | The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2021. corrected publication 2021 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2021. corrected publication 2021. |
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| DOI | 10.1007/s00417-021-05452-1 |
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| Keywords | Indocyanine green angiography Fleiss Kappa coefficient Fluorescein angiography Optical coherence tomography Central serous chorioretinopathy Multimodal imaging Inter-rater agreement |
| Language | English |
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| References | Arora, Kulikov, Maltsev (CR10) 2021 van Rijssen, van Dijk, Yzer (CR13) 2019; 73 Balaratnasingam, Freund, Tan (CR2) 2016; 123 van Dijk, Boon (CR12) 2021; 84 Daruich, Matet, Dirani (CR1) 2015; 48 Chhablani, Cohen (CR6) 2020; 4 Ng, Ho, Chen (CR11) 2021 Nicholson, Noble, Forooghian (CR4) 2013; 58 Fleiss (CR7) 1971; 76 Jabs, Dick, Doucette (CR8) 2018; 186 Chandra, Rasheed, Sen (CR9) 2021 Singh, Matet, van Dijk (CR5) 2019; 103 Mrejen, Balaratnasingam, Kaden (CR3) 2019; 126 S Mrejen (5452_CR3) 2019; 126 A Daruich (5452_CR1) 2015; 48 DA Jabs (5452_CR8) 2018; 186 J Chhablani (5452_CR6) 2020; 4 EHC van Dijk (5452_CR12) 2021; 84 DS Ng (5452_CR11) 2021 B Nicholson (5452_CR4) 2013; 58 JL Fleiss (5452_CR7) 1971; 76 C Balaratnasingam (5452_CR2) 2016; 123 TJ van Rijssen (5452_CR13) 2019; 73 S Arora (5452_CR10) 2021 SR Singh (5452_CR5) 2019; 103 S Chandra (5452_CR9) 2021 34741662 - Graefes Arch Clin Exp Ophthalmol. 2022 Feb;260(2):703. doi: 10.1007/s00417-021-05484-7. |
| References_xml | – volume: 76 start-page: 378 issue: 5 year: 1971 end-page: 382 ident: CR7 article-title: Measuring nominal scale agreement among many raters publication-title: Psychol Bull doi: 10.1037/h0031619 – volume: 4 start-page: 1043 issue: 11 year: 2020 end-page: 1046 ident: CR6 article-title: Multimodal Imaging-Based Central Serous Chorioretinopathy Classification publication-title: Ophthalmol Retina doi: 10.1016/j.oret.2020.07.026 – volume: 84 start-page: 100955 year: 2021 ident: CR12 article-title: Serous business: Delineating the broad spectrum of diseases with subretinal fluid in the macula publication-title: Prog Retin Eye Res doi: 10.1016/j.preteyeres.2021.100955 – year: 2021 ident: CR10 article-title: Implementation of the new multimodal imaging-based classification of central serous chorioretinopathy publication-title: Eur J Ophthalmol doi: 10.1177/11206721211013651 – volume: 123 start-page: 1541 issue: 7 year: 2016 end-page: 1552 ident: CR2 article-title: Bullous Variant of Central Serous Chorioretinopathy: Expansion of Phenotypic Features Using Multimethod Imaging publication-title: Ophthalmology doi: 10.1016/j.ophtha.2016.03.017 – year: 2021 ident: CR11 article-title: Optical Coherence Tomography Angiography Compared with Multimodal Imaging for Diagnosing Neovascular Central Serous Chorioretinopathy publication-title: Am J Ophthalmol doi: 10.1016/j.ajo.2021.05.029 – volume: 73 start-page: 100770 year: 2019 ident: CR13 article-title: Central serous chorioretinopathy: Towards an evidence-based treatment guideline publication-title: Prog Retin Eye Res doi: 10.1016/j.preteyeres.2019.07.003 – volume: 103 start-page: 737 issue: 6 year: 2019 end-page: 742 ident: CR5 article-title: Discrepancy in current central serous chorioretinopathy classification publication-title: Br J Ophthalmol doi: 10.1136/bjophthalmol-2018-312435 – volume: 186 start-page: 19 year: 2018 end-page: 24 ident: CR8 article-title: Interobserver Agreement Among Uveitis Experts on Uveitic Diagnoses: The Standardization of Uveitis Nomenclature Experience publication-title: Am J Ophthalmol doi: 10.1016/j.ajo.2017.10.028 – year: 2021 ident: CR9 article-title: Inter-rater reliability for diagnosis of geographic atrophy using spectral domain OCT in age-related macular degeneration publication-title: Eye doi: 10.1038/s41433-021-01490-5 – volume: 48 start-page: 82 year: 2015 end-page: 118 ident: CR1 article-title: Central serous chorioretinopathy: Recent findings and new physiopathology hypothesis publication-title: Prog Retin Eye Res doi: 10.1016/j.preteyeres.2015.05.003 – volume: 126 start-page: 576 issue: 4 year: 2019 end-page: 588 ident: CR3 article-title: Long-term Visual Outcomes and Causes of Vision Loss in Chronic Central Serous Chorioretinopathy publication-title: Ophthalmology doi: 10.1016/j.ophtha.2018.12.048 – volume: 58 start-page: 103 issue: 2 year: 2013 end-page: 126 ident: CR4 article-title: Central serous chorioretinopathy: update on pathophysiology and treatment publication-title: Surv Ophthalmol doi: 10.1016/j.survophthal.2012.07.004 – volume: 48 start-page: 82 year: 2015 ident: 5452_CR1 publication-title: Prog Retin Eye Res doi: 10.1016/j.preteyeres.2015.05.003 – volume: 73 start-page: 100770 year: 2019 ident: 5452_CR13 publication-title: Prog Retin Eye Res doi: 10.1016/j.preteyeres.2019.07.003 – volume: 123 start-page: 1541 issue: 7 year: 2016 ident: 5452_CR2 publication-title: Ophthalmology doi: 10.1016/j.ophtha.2016.03.017 – year: 2021 ident: 5452_CR11 publication-title: Am J Ophthalmol doi: 10.1016/j.ajo.2021.05.029 – volume: 76 start-page: 378 issue: 5 year: 1971 ident: 5452_CR7 publication-title: Psychol Bull doi: 10.1037/h0031619 – volume: 126 start-page: 576 issue: 4 year: 2019 ident: 5452_CR3 publication-title: Ophthalmology doi: 10.1016/j.ophtha.2018.12.048 – volume: 103 start-page: 737 issue: 6 year: 2019 ident: 5452_CR5 publication-title: Br J Ophthalmol doi: 10.1136/bjophthalmol-2018-312435 – year: 2021 ident: 5452_CR9 publication-title: Eye doi: 10.1038/s41433-021-01490-5 – volume: 4 start-page: 1043 issue: 11 year: 2020 ident: 5452_CR6 publication-title: Ophthalmol Retina doi: 10.1016/j.oret.2020.07.026 – volume: 186 start-page: 19 year: 2018 ident: 5452_CR8 publication-title: Am J Ophthalmol doi: 10.1016/j.ajo.2017.10.028 – year: 2021 ident: 5452_CR10 publication-title: Eur J Ophthalmol doi: 10.1177/11206721211013651 – volume: 84 start-page: 100955 year: 2021 ident: 5452_CR12 publication-title: Prog Retin Eye Res doi: 10.1016/j.preteyeres.2021.100955 – volume: 58 start-page: 103 issue: 2 year: 2013 ident: 5452_CR4 publication-title: Surv Ophthalmol doi: 10.1016/j.survophthal.2012.07.004 – reference: 34741662 - Graefes Arch Clin Exp Ophthalmol. 2022 Feb;260(2):703. doi: 10.1007/s00417-021-05484-7. |
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Validation of a recently described central serous chorioretinopathy (CSCR) classification system and assessment of levels of agreement among 10 retina... Validation of a recently described central serous chorioretinopathy (CSCR) classification system and assessment of levels of agreement among 10 retina... PurposeValidation of a recently described central serous chorioretinopathy (CSCR) classification system and assessment of levels of agreement among 10 retina... |
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| SubjectTerms | Agreements Angiography Central Serous Chorioretinopathy - diagnosis Choroid Classification Cross-Sectional Studies Eye Fluorescein Fluorescein Angiography - methods Humans Kappa coefficient Medicine Medicine & Public Health Multimodal Imaging Ophthalmology Patients Retina Retinal Disorders Retrospective Studies Statistical analysis Tomography, Optical Coherence - methods |
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| Title | Validation of central serous chorioretinopathy multimodal imaging-based classification system |
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