Immunobiology and pathogenesis of hepatitis B virus infection

Hepatitis B virus (HBV) is a non-cytopathic, hepatotropic virus with the potential to cause a persistent infection, ultimately leading to cirrhosis and hepatocellular carcinoma. Over the past four decades, the basic principles of HBV gene expression and replication as well as the viral and host dete...

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Bibliographic Details
Published in:	Nature reviews. Immunology Vol. 22; no. 1; pp. 19 - 32
Main Authors:	Iannacone, Matteo, Guidotti, Luca G
Format:	Journal Article
Language:	English
Published:	England Nature Publishing Group 01.01.2022
Subjects:	Adaptive immunity CD8 antigen CD8-Positive T-Lymphocytes Cell differentiation Chronic infection Cirrhosis Fibrosis Gene expression Genomes Hemodynamics Hepatitis Hepatitis B Hepatitis B surface antigen Hepatitis B virus - genetics Hepatitis B, Chronic - pathology Hepatocellular carcinoma Humans Immune clearance Immune response Infections Inflammation Liver cancer Liver cirrhosis Liver diseases Liver Neoplasms - etiology Lymphocytes Lymphocytes T Pathogenesis Viruses
ISSN:	1474-1733, 1474-1741, 1474-1741
Online Access:	Get full text
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