High-Dose Intravenous Immunoglobulin as a Therapeutic Option for Deteriorating Patients With Coronavirus Disease 2019

Abstract The outbreak of coronavirus disease 2019 (COVID-19) has spread rapidly in China. Until now, no definite effective treatment has been identified. We reported on 3 patients with severe COVID-19 who received high-dose intravenous immunoglobulin (IVIg) with satisfactory recovery. Based on these...

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Bibliographic Details
Published in:Open forum infectious diseases Vol. 7; no. 3; p. ofaa102
Main Authors: Cao, Wei, Liu, Xiaosheng, Bai, Tao, Fan, Hongwei, Hong, Ke, Song, Hui, Han, Yang, Lin, Ling, Ruan, Lianguo, Li, Taisheng
Format: Journal Article
Language:English
Published: US Oxford University Press 01.03.2020
Subjects:
Brief Report
immunomodulation
high-dose intravenous immunoglobulin
coronavirus disease 2019
ISSN:2328-8957, 2328-8957
Online Access:Get full text
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Summary:Abstract The outbreak of coronavirus disease 2019 (COVID-19) has spread rapidly in China. Until now, no definite effective treatment has been identified. We reported on 3 patients with severe COVID-19 who received high-dose intravenous immunoglobulin (IVIg) with satisfactory recovery. Based on these observations, randomized studies of high-dose IVIg should be considered in deteriorating patients infected with COVID-19.
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Lianguo Ruan and Taisheng Li Equal contribution
ISSN:2328-8957
2328-8957
DOI:10.1093/ofid/ofaa102