Nonalcoholic steatohepatitis: the role of peroxisome proliferator-activated receptors

The increasing epidemic of obesity worldwide is linked to serious health effects, including increased prevalence of type 2 diabetes mellitus, cardiovascular disease and nonalcoholic fatty liver disease (NAFLD). NAFLD is the liver manifestation of the metabolic syndrome and includes the spectrum of l...

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Bibliographic Details
Published in:	Nature reviews. Gastroenterology & hepatology Vol. 18; no. 1; pp. 24 - 39
Main Authors:	Francque, Sven, Szabo, Gyongyi, Abdelmalek, Manal F., Byrne, Christopher D., Cusi, Kenneth, Dufour, Jean-François, Roden, Michael, Sacks, Frank, Tacke, Frank
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 01.01.2021 Nature Publishing Group
Subjects:	692/4020/4021/1607/2751 692/699/1503/1607/1605 Adipose tissue Beta cells Biomedicine Cardiovascular diseases Cardiovascular system Cell activation Cirrhosis Diabetes mellitus (non-insulin dependent) Disease Disease Progression Fat metabolism Fatty liver Fibrosis Gastroenterology Glucose metabolism Hepatology Humans Inflammation Inflammation - etiology Inflammation - physiopathology Liver Liver cirrhosis Liver diseases Medicine Medicine & Public Health Metabolic syndrome Metabolic Syndrome - complications Metabolic Syndrome - metabolism Metabolic Syndrome - physiopathology Microbiomes Non-alcoholic Fatty Liver Disease - drug therapy Non-alcoholic Fatty Liver Disease - etiology Non-alcoholic Fatty Liver Disease - metabolism Non-alcoholic Fatty Liver Disease - physiopathology Obesity - complications Obesity - physiopathology Pancreas Peroxisome proliferator-activated receptors Peroxisome Proliferator-Activated Receptors - agonists Peroxisome Proliferator-Activated Receptors - metabolism Review Article Steatosis
ISSN:	1759-5045, 1759-5053, 1759-5053
Online Access:	Get full text
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