Repressing expression of difficult‐to‐express recombinant proteins during the selection process increases productivity of CHO stable pools

NRC publication: Yes

Saved in:

Bibliographic Details
Published in:	Biotechnology and bioengineering Vol. 120; no. 10; pp. 2840 - 2852
Main Authors:	Maltais, Jean‐Sébastien, Lord Dufour, Simon, Morasse, Audrey, Stuible, Matthew, Loignon, Martin, Durocher, Yves
Format:	Journal Article
Language:	English
Published:	United States Wiley 01.10.2023 Wiley Subscription Services, Inc
Subjects:	Antibodies Bispecific antibodies Cell surface receptors Cell viability Cellular stress response CHO cells cumate Cytokines difficult‐to‐express protein Endoplasmic reticulum ER stress High mobility group proteins HMGB1 protein inducible expression Metabolism Monoclonal antibodies produc Productivity Proteins Receptors ER stress difficult-to-express protein inducible expression cumate productivity CHO cells
ISSN:	1097-0290, 0006-3592, 1097-0290
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!