Bias Due to Within-Subject Exposure Dependency With or Without Bias Due to Lack of Pairwise Exchangeability When Exposure Is Chronic in Case-Crossover and Case–Time-Control Studies: A Simulation Study

Abstract The case-crossover study design has been proposed as a suitable design for use when a brief exposure causes a transient change in risk of an acute-onset disease. In pharmacoepidemiology, the condition of “brief exposure” is rarely satisfied because medication use is often chronic or success...

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Bibliographic Details

Published in:	American journal of epidemiology Vol. 192; no. 10; pp. 1701 - 1711
Main Authors:	Kubota, Kiyoshi, Kelly, Thu-Lan
Format:	Journal Article
Language:	English
Published:	United States Oxford University Press 10.10.2023
Subjects:	self-controlled studies case-crossover studies case–time-control studies bias self-controlled studybias case-time-control study case-crossover study
ISSN:	0002-9262, 1476-6256, 1476-6256
Online Access:	Get full text
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