Proteomic profiling of neutrophils and plasma in community-acquired pneumonia reveals crucial proteins in diverse biological pathways linked to clinical outcome

Neutrophils play a dichotomous role in community-acquired pneumonia (CAP), providing protection and potentially causing damage. Existing research on neutrophil function in CAP relies on animal studies, leaving a gap in patient-centered investigations. We used mass spectrometry to characterize the ne...

Celý popis

Uloženo v:

Podrobná bibliografie
Vydáno v:	Frontiers in immunology Ročník 15; s. 1470383
Hlavní autoři:	Michels, Erik H. A., Chouchane, Osoul, de Brabander, Justin, de Vos, Alex F., Faber, Daniël R., Douma, Renée A., Smit, Eva R., Wiersinga, W. Joost, Biggelaar, Maartje van den, Poll, Tom van der, Hoogendijk, Arie J.
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Switzerland Frontiers Media SA 2024 Frontiers Media S.A
Témata:	Age differences Aged Animal models Community-Acquired Infections - blood Community-Acquired Infections - immunology community-acquired pneumonia Cytoskeleton Female general ward Gram-positive bacteria Hospitals Humans Infections Leukocytes (neutrophilic) Lysates Male Mass spectrometry Mass spectroscopy Medical research Middle Aged neutrophil Neutrophils Neutrophils - immunology Neutrophils - metabolism Pathogens Patients Peptides Plasma Platelets Pneumonia Pneumonia - blood Pneumonia - immunology Pneumonia - metabolism Prospective Studies Proteins Proteome Proteomes Proteomics Proteomics - methods Respiratory diseases RNA processing Scientific imaging Sensitivity analysis innate immunity pneumonia proteomics mass spectrometry community-acquired pneumonia neutrophil general ward
ISSN:	1664-3224, 1664-3224
On-line přístup:	Získat plný text
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!

Buďte první, kdo okomentuje tento záznam!